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Hongping Zhu
Peking University
8Publications
2H-index
10Citations
Publications 8
Newest
#1Dongjing Liu (PKU: Peking University)H-Index: 2
#2Mengying Wang (PKU: Peking University)H-Index: 3
Last.Terri H. Beaty (Johns Hopkins University)H-Index: 65
view all 11 authors...
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#1Wenyong LiH-Index: 1
#2Mengying WangH-Index: 3
Last.Terri H. Beaty (UB: University of Baltimore)H-Index: 2
view all 10 authors...
1 CitationsSource
#1Ren Zhou (PKU: Peking University)H-Index: 1
#2Mengying Wang (PKU: Peking University)H-Index: 3
Last.Terri H. Beaty (Johns Hopkins University)H-Index: 65
view all 11 authors...
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is one of common birth defects in China, with genetic and environmental components contributing to the etiology. Genome wide association studies (GWASs) have identified SPRY1 and SPRY2 to be associated with NSCL/P among Chinese populations. This study aimed to further explore potential genetic effect and gene—environment interaction among SPRY genes based on haplotype analysis, using 806 Chinese case—parent NSCL/P trios drawn from an ...
1 CitationsSource
#1Mengying Wang (PKU: Peking University)H-Index: 3
#2Dongjing Liu (PKU: Peking University)H-Index: 2
Last.Terri H. Beaty (Johns Hopkins University)H-Index: 65
view all 10 authors...
Source
#1Dongjing LiuH-Index: 2
#2Holger Schwender (HHU: University of Düsseldorf)H-Index: 20
Last.Terri H. BeatyH-Index: 65
view all 10 authors...
BackgroundSmall ubiquitin-like modification, also known as sumoylation, is a crucial post-translational regulatory mechanisms involved in development of the lip and palate. Recent studies reported two sumoylation target genes, MSX1 and TP63, to have achieved genome-wide level significance in tests of association with nonsyndromic clefts. Here, we performed a candidate gene analysis considering gene-gene and gene-environment interaction for SUMO1, MSX1, and TP63 to further explore the etiology of...
Source
#1Mengying Wang (PKU: Peking University)H-Index: 3
#2Yuan Yuan (PKU: Peking University)H-Index: 3
Last.Terri H. Beaty (Johns Hopkins University)H-Index: 65
view all 11 authors...
Background Orofacial clefts (OFCs) are common human birth defects in China. However, studies on the prevalence of OFCs present inconsistent results. The overall prevalence and geographic distribution of OFCs are poorly described in China. Thus, we conducted a systematic review and meta-analysis to estimate the prevalence of OFCs. Methods The systematic review and meta-analysis were conducted on the basis of an established protocol (PROSPERO 2015: CRD42015030198). We systematically searched for a...
4 CitationsSource
#1Dongjing Liu (PKU: Peking University)H-Index: 2
#2Hong Wang (PKU: Peking University)H-Index: 15
Last.Terri H. Beaty (Johns Hopkins University)H-Index: 65
view all 14 authors...
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is a common birth defect with a complex and heterogeneous etiology. A recent genome-wide association study (GWAS) among Chinese populations has identified a new region at 16p13.3 as being associated with NSCL/P, which requires further replication. Here, we attempted to replicate and further clarify the genetic association between this region and NSCL/P, as well as testing for potential gene-gene (G × G) and gene-environment (G × E) in...
4 CitationsSource
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