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S. M. A. Abidi
Aligarh Muslim University
39Publications
8H-index
193Citations
Publications 41
Newest
#1Abdur Rehman (AMU: Aligarh Muslim University)H-Index: 3
#2Rizwan Ullah (AMU: Aligarh Muslim University)H-Index: 4
Last.S. M. A. Abidi (AMU: Aligarh Muslim University)H-Index: 8
view all 8 authors...
Abstract Fasciolosis is a neglected tropical disease caused by the liver fluke Fasciola gigantica. The absence of successful vaccine and emerging resistance in flukes against the drug of choice, triclabendazole, has initiated the search for alternatives including phyto-therapeutic approaches. Curcumin and thymoquinone, the active ingredients of Curcuma longa and Nigella sativa plants respectively, were first screened for their binding affinity with Glutathione-S-transferase (GST) molecule throug...
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#1Abdur Rehman (AMU: Aligarh Muslim University)H-Index: 3
#2Rizwan Ullah (AMU: Aligarh Muslim University)H-Index: 4
Last.S. M. A. Abidi (AMU: Aligarh Muslim University)H-Index: 8
view all 6 authors...
In order to ensure global food security a rationale approach is required to control all those factors which directly or indirectly affect the food productivity. The neglected helminthic diseases alone are responsible for huge economic losses to the agrarian stakeholders. The problem is further compounded by the emerging drug resistance in flukes against the commonly used anthelmintics like triclabendazole. Therefore, the search for alternatives including the nano-based approaches has become a ne...
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#1M. LalH-Index: 6
#2Mazhar HussainH-Index: 31
Last.Adib RizviH-Index: 10
view all 8 authors...
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#1S. M. A. Abidi (AMU: Aligarh Muslim University)H-Index: 8
#2Kavita Singh (AMU: Aligarh Muslim University)
Last.M.A. Beg (AMU: Aligarh Muslim University)
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Paramphistomosis is a chronic, debilitating parasitic disease of livestock prevalent in the tropical and sub-tropical countries. Globally there is a heavy reliance on anthelmintics but concerns over drug resistance encourage the search for new leads. Metalloproteinases play a significant role in the biology and life cycle of parasitic helminths. The efficacy of metalloproteinase inhibitor, 1,10-Phenanthroline (1,10-phe) which is commonly used as a specific enzyme inhibitor in biochemical assays,...
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#1Abdur Rehman (AMU: Aligarh Muslim University)H-Index: 3
#2Rizwan Ullah (AMU: Aligarh Muslim University)H-Index: 4
Last.S. M. A. Abidi (AMU: Aligarh Muslim University)H-Index: 8
view all 8 authors...
Abstract The helminth parasites possess great capabilities to adapt themselves within their hosts and also develop strategies to render the commonly used anthelmintics ineffective leading to the development of resistance against these drugs. Besides using anthelmintics the natural products have also been tested for their anti-parasitic effects. Therapeutic efficacy of honey bee venom (HBV) has been tested in various ailments including some protozoal infections but very little is known about its ...
1 CitationsSource
#1M. A. Hannan Khan (AMU: Aligarh Muslim University)H-Index: 3
#2Rizwan Ullah (AMU: Aligarh Muslim University)H-Index: 4
Last.S. M. A. Abidi (AMU: Aligarh Muslim University)H-Index: 8
view all 6 authors...
The digenetic trematode Fasciola gigantica is a parasite of great agricultural and economic importance. Along with Fasciola hepatica, F. gigantica incurs huge economic losses to the agricultural sector. Because of unavailability of an effective and commercial vaccine, the earliest diagnosis of the disease is the only way to control the disease. The conventional coprological techniques are able to detect the disease only after the parasites get matured and starts releasing their eggs with the fae...
5 CitationsSource
#1M. A. Hannan Khan (AMU: Aligarh Muslim University)H-Index: 3
#2P. A. A. Shareef (AMU: Aligarh Muslim University)H-Index: 1
Last.S. M. A. Abidi (AMU: Aligarh Muslim University)H-Index: 8
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A number of parasitic platyhelminthes are known to cause genotoxicity in humans and animals. However no such information is available on tropical liver fluke, Fasciola gigantica, which incurs huge economic losses worldwide. In the present study the genotoxic potential of F. gigantica infection in rabbits, experimentally infected with the metacercarial cysts of this parasite, has been investigated using the standard comet assay and micronucleus (MNi) test on the isolated hepatocytes and the whole...
2 CitationsSource
#1Rizwan UllahH-Index: 4
#2Abdur RehmanH-Index: 3
Last.S. M. A. AbidiH-Index: 8
view all 9 authors...
Fasciolosis an economically important global disease of ruminants in the temperate and tropical regions, caused by Fasciola hepatica and F. gigantica, respectively, also poses a potential zoonotic threat. In India alone it causes huge losses to stakeholders. Anthelmintics including triclabendazole have been used to control this menace but the emerging resistance against the available compounds necessitates identification of novel and alternative therapeutic measures involving plant derived natur...
10 CitationsSource
#1Yasir Akhtar Khan (AMU: Aligarh Muslim University)H-Index: 4
#2Mohd Abdul Hannan Khan (AMU: Aligarh Muslim University)H-Index: 1
Last.S. M. A. Abidi (AMU: Aligarh Muslim University)H-Index: 8
view all 3 authors...
The digenetic trematodes, Fasciola gigantica and Gigantocotyle explanatum, belonging to the family Fasciolidae and Paramphistomidae respectively, have been often found to concurrently infect the liver of Indian water buffalo Bubalus bubalis, causing serious pathological damage to the vital organ, incurring huge economic losses. In the present study the soluble gene products of both F. gigantica and G. explanatum were analyzed by 2 dimen- sional polyacrylamide gel electrophoresis. The soluble pro...
4 CitationsSource
#1M. K. SaifullahH-Index: 6
#2Gul AhmadH-Index: 3
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