Fatemeh Mirzaei
Kermanshah University of Medical Sciences
Publications 10
#1Fatemeh MirzaeiH-Index: 2
#2Mozafar KhazaeiH-Index: 14
Last.Cyrus JaliliH-Index: 7
view all 5 authors...
#1Hamidreza KomakiH-Index: 4
#2Nafiseh FarajiH-Index: 1
Last.Fatemeh MirzaeiH-Index: 2
view all 7 authors...
Oxidative stress plays a key role in contributing to β-amyloid (Aβ) deposition in Alzheimer's disease (AD). Coenzyme Q10 (Q10) is a powerful antioxidant that buffers the potential adverse consequences of free radicals. In this study, we investigated the neuroprotective effects of Q10 on Aβ-induced impairment in hippocampal long-term potentiation (LTP), a widely researched model of synaptic plasticity, which occurs during learning and memory, in a rat model of AD. In this study, 50 adult male Wis...
1 CitationsSource
Purpose: This study evaluated the effects of titanium dioxide nanoparticles (TiO2 NPs) on liver and intestine of normal rats. Methods: Male rats were divided into four groups as follows: 1) control rats, 2) control rats that orally received 10 mg/kg TiO 2 NPs, 3) control rats that orally received 50 mg/kg TiO 2 NPs, and 4) control rats that orally received 100 mg/kg TiO 2 NPs. After 30 days, the NLRP3 inflammasome pathway (NLRP3, caspase-1, and IL-1β), antioxidant pathway (superoxide dismutase S...
2 CitationsSource
#1Iraj SalehiH-Index: 15
#2Ebrahim Zarrinkalam (IAU: Islamic Azad University)H-Index: 3
Last.Sara Soleimani AslH-Index: 10
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Objectives: The aim of this study was to evaluate the effects of resistance, endurance, and concurrent exercise on oxidative stress markers and histological changes of the intestine after morphine withdrawal in rats. Methods: A total of 30 male Wistar rats were randomly divided into 5 groups (n=6) including healthy control, withdrawal (rat received morphine for 21 days and 8 weeks of withdrawal period), withdrawal + endurance exercises, withdrawal + resistance exercises, and withdrawal + concurr...
#2Fatemeh Mirzaei (Kermanshah University of Medical Sciences)H-Index: 2
Last.Amir Mirzaei (Concordia University)H-Index: 7
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Aim: The present study was carried out to determine the effects of ZnO nanoparticles (ZnO-NPs) on intestinal function and pathophysiological alteration. Materials & methods: ZnO-NPs were synthesized and their characterizations were performed using various techniques. The Wistar male rats fed with normal diet and/or high fat diet (HFD) for 8 weeks and then orally received ZnO-NPs (5, 50 and 100 mg/kg bodyweight) for 28 days. The oxidative stress (SOD, CAT, GPx), inflammatory (TNF-α, iNOS) and apo...
2 CitationsSource
#2Iraj KhodadadiH-Index: 10
Last.Mohammad Taghi Goodarzi (IAU: Islamic Azad University)H-Index: 16
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BACKGROUND: High lipid accumulation in hepatocyte and blood vessels can lead to non-alcoholic fatty liver disease (NAFLD) and heart diseases, respectively. These disorders are the main reasons of mortality in various countries. In this experiment, we evaluated the effect of leaf extracts of Anethum graveolens (AG), also known as Dill, and AG tablet on expression of low-density lipoprotein receptor (LDLR) and liver lipid in hypercholesterolemic hamsters. METHODS: In this experimental study, 36 ma...
#1Fatemeh Mirzaei (Kermanshah University of Medical Sciences)H-Index: 2
#2Mozafar Khazaei (Kermanshah University of Medical Sciences)H-Index: 14
Last.Cyrus Jalili (Kermanshah University of Medical Sciences)H-Index: 7
view all 5 authors...
Both dyslipidemia and Alzheimer disease (AD) are associated with aging. In this study, the effects of virgin coconut oil (VCO) on inflammasome and oxidative stress in Alzheimer's model (receiving Amyloid-β (Aβ)) and high-fat diet (HFD) model were determined. A total of 120 male Wistar rats, were divided into 12 groups (n = 10), including; healthy control, sham surgery, sham surgery receiving normal saline, HFD, HFD + 8% VCO, HFD + 10% VCO, Aβ received rats, Aβ + 8%VCO, Aβ + 10%VCO, HFD + Aβ, HFD...
4 CitationsSource
#2Mona PourjafarH-Index: 2
Last.Fatemeh Mirzaei (Kermanshah University of Medical Sciences)H-Index: 2
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Background: Although acetaminophen (APAP) is considered safe at therapeutic doses, intake of high amounts of this drug can cause liver failure. In the present experiment, we examined the hepatoprotective effects of resveratrol (RES) in HepG2 cells and rat liver. Objectives: This study aimed to evaluate the influence of RES on liver function in rat model of necrosis and HepG2 cells. Materials and Methods: In this study, rats were randomly assigned into 4 groups (7 rats in each group) as follows; ...
#2Iraj KhodadadiH-Index: 10
Last.Mohammad Taghi GoodarziH-Index: 16
view all 6 authors...
The research was aimed at evaluating the antiglycation, antioxidant, and hepatoprotective properties of methanolic extract of Anethum graveolens (dill). The antioxidant properties, photochemical characteristics, and antiglycation effects of dill extract were measured. Carbon tetrachloride-induced hepatotoxic rats were used to show the hepatoprotective activity of dill leaves. Different concentration of dill extract (0.032, 0.065, 0.125, 0.25, 0.5, and 1 mg/mL) showed potential antioxidant abilit...
5 CitationsSource
#2Fatemeh MirzaeiH-Index: 2