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Rusmir Husic
Medical University of Graz
UltrasoundPhysical therapyProspective cohort studyPsoriatic arthritisMedicine
25Publications
7H-index
177Citations
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Publications 25
Newest
#1Philipp Bosch (Medical University of Graz)
#2Rusmir Husic (Medical University of Graz)H-Index: 7
Last. Christian Dejaco (Medical University of Graz)H-Index: 29
view all 9 authors...
Background: Tender and Swollen Joint Counts (TJC, SJC) are items of disease activity scores in rheumatoid arthritis (RA) and psoriatic arthritis (PsA). Recent studies suggest that TJC do not adequately reflect ongoing inflammation in RA when using Ultrasound (US) as a reference standard, and that pain might be due to other, non-inflammatory causes.1, 2 In PsA, the role of tenderness and swelling of joints for reflecting active inflammation has not been well studied so far. Objectives: To evaluat...
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#1Angelika Lackner (University of Graz)H-Index: 5
#2Daniel HeberH-Index: 2
Last. Winfried Graninger (University of Graz)H-Index: 40
view all 11 authors...
OBJECTIVES: The aim of this prospective study was to examine whether ultrasound or clinical abnormalities at enthesal sites predict radiographic progression at entheses in psoriatic arthritis (PsA). METHODS: Consecutive PsA patients were included and subjected to clinical and ultrasound assessments at 14 entheses at baseline, 6 and 12 months. Radiographs were performed at 0 and 12 months. By US, we investigated structural (erosions, osteophytes) and inflammatory changes [grey scale (0-32) and po...
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#1Philipp Bosch (University of Graz)
#2Rusmir Husic (University of Graz)H-Index: 7
Last. Christian Dejaco (University of Graz)H-Index: 29
view all 9 authors...
OBJECTIVE: To evaluate low disease activity (LDA) cut-offs in psoriatic arthritis (PsA) using ultrasound. METHODS: Eighty-three PsA patients underwent clinical and ultrasound examinations at two visits. LDA was assessed using the Disease Activity index for Psoriatic Arthritis (DAPSA ⩽ 14), the Psoriatic ArthritiS Disease Activity Score (PASDAS ⩽ 3.2), the Composite Psoriatic Disease Activity Index ⩽ 4, the DAS28-CRP ⩽ 2.8 and the minimal disease activity criteria. Ultrasound was performed at 68 ...
Source
#1Barbara Dreo (Medical University of Graz)
#2Rusmir Husic (Medical University of Graz)H-Index: 7
Last. Martin H. Stradner (Medical University of Graz)H-Index: 12
view all 8 authors...
Background: In rheumatoid arthritis (RA) stratification is considered an important step towards the development of patient-tailored therapeutic concepts. The fact that less than 50% of RA patients experience a substantial improvement in response to any single biologic therapy has brought up the idea that yet unidentified subtypes of RA (endotypes) might exist. This concept is in line with distinct microscopic patterns of synovitis found in biopsies of RA joints.[1] Furthermore, a subset of RA pa...
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Background In clinical trials radiographic damage is frequently quantified by conventional x-ray but neither the thoracic spine nor the posterior parts of the vertebral column including the intervertebral joints, the vertebral arch and the spinous process can be evaluated reliably with this instrument. Bone inflammation and areas of enthesitis can easily be detected by magnetic tomography imaging (MRI) and the introduction of high-resolution 3-tesla MRI allows analysis of bone structures more pr...
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#1Philipp Bosch (University of Graz)H-Index: 1
#2Rusmir Husic (University of Graz)H-Index: 7
Last. Christian Dejaco (University of Graz)H-Index: 29
view all 9 authors...
Background Cut offs for low disease activity (LDA) using psoriatic arthritis (PsA) specific composite scores have recently been proposed.1–3 Whether these definitions adequately reflect the absence of inflammation is unknown. Objectives To evaluate these definitions against a low level of activity according to ultrasound examination. Methods We performed a prospective study on 83 PsA patients undergoing clinical and ultrasound examinations at two study visits scheduled 6 months apart. LDA was as...
Source
#1Johannes Fessler (Medical University of Graz)H-Index: 7
#2Rusmir Husic (Medical University of Graz)H-Index: 7
Last. Christian Dejaco (Medical University of Graz)H-Index: 29
view all 12 authors...
Objective: T-cells are critical players in the pathogenesis of osteoporosis in patients with rheumatoid Arthritis (RA). Premature senescence of lymphocytes including accumulation of senescent CD4+ T-cells is a hallmark feature of RA. Whether T-cell senescence is associated with bone loss in RA patients is elusive so far. Methods: Prospective study of consecutive patients with RA (n=107), patients with primary osteopenia/-porosis (n=75) and healthy individuals (n=38). Bone mineral density (BMD) w...
3 CitationsSource
#1Christian Dejaco (University of Graz)H-Index: 29
#2Andreas StadlmayrH-Index: 13
Last. Jochen ZwerinaH-Index: 58
view all 16 authors...
Background Chronic arthropathy occurs in approximately two thirds of patients with hereditary haemochromatosis (HH). The aim was to study inflammatory and structural lesions in patients with HH with (HH-A) and without arthropathy (HH-WA) using ultrasonography.
3 CitationsSource
#1Rusmir Husic (University of Graz)H-Index: 7
#2Angelika Lackner (University of Graz)H-Index: 5
Last. Christian Dejaco (University of Graz)H-Index: 29
view all 5 authors...
Abstract Position of joints might influence the result of US examination in patients with RA. The purpose of this work was to compare grey-scale (GS) and power Doppler (PWD) findings obtained in neutral vs flat position of hands. A cross-sectional study of 42 RA patients with active disease. Two dimensional and 3D sonography of wrists and MCP joints were conducted in two different joint positions: neutral position, which is a slight flexion of the fingers with relaxed extensor muscles; and flat ...
2 CitationsSource
#1Johannes Fessler (Medical University of Graz)H-Index: 7
#2Andrea Raicht (Medical University of Graz)H-Index: 2
Last. Christian Dejaco (Medical University of Graz)H-Index: 29
view all 10 authors...
Objective: Premature senescence of lymphocytes is a hallmark of inflammatory rheumatic diseases such as Rheumatoid Arthritis (RA). Early T-cell aging affects conventional T-cells but is presumably not limited to this cell population; rather it might also occur in the Treg compartment. In RA, Tregs fail to halt aberrant immune reactions and disease progression. Whether this is associated with early Treg senescence leading to phenotypic and functional changes of this subset is elusive so far. Meth...
8 CitationsSource
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