Ming Li
University of South Alabama
Publications 38
#1Stephen W. SchafferH-Index: 34
#2Ming LiH-Index: 24
#2Randy KangH-Index: 1
Last.Ming LiH-Index: 24
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This paper describes the challenges faced in predicting the reliability of very large scale integration (VLSI) circuits. Currently, lots of trial-and-errors are still needed for the parameters selected to develop a neural network prediction model, whose result is with a great deal of uncertainty. The objective of this paper is to provide a novel and practical approach to design a reliability prediction model using neural network. We propose a seven-step procedure to formulate an optimal neural n...
3 CitationsSource
#2Randy KangH-Index: 1
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This paper introduces a guidance, which is displayed by a flow chart, for the process reliability data comparison of advanced semiconductor technologies. The present semiconductor manufacturing process is very complex and its quality control requirement also becomes more and more strict. Different reliability data may analyzed by different methods considering both engineering and statistical evidence so we can best assess process reliability performance not only considering the lifetime requirem...
#1Suresh C. SikkaH-Index: 44
#2Ming LiH-Index: 24
Last.Wayne J.G. HellstromH-Index: 63
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The present study investigated the effect of the organophosphate, dichlorvos (DDVP), on ocular function and cholinesterase activity in guinea pigs, using a single-animal-head-only vapor exposure system. All animals exhibited signs of mild organophosphate poisoning (e.g., salivation, chewing, lacrimation, urination, defecation, and rhinorhea) after the 20-min exposure, regardless of the DDVP exposure concentration (e.g., 35 mg/m3, 55 mg/m3, and 75 mg/m3). Pupil constriction or miosis was the most...
3 CitationsSource
#1James T. Taylor (Tulane University)H-Index: 9
#2Xiangbin ZengH-Index: 5
Last.Ming LiH-Index: 24
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Regulation of intracellular calcium is an important signaling mechanism for cell proliferation in both normal and cancerous cells. In normal epithelial cells, free calcium concentration is essential for cells to enter and accomplish the S phase and the M phase of the cell cycle. In contrast, cancerous cells can pass these phases of the cell cycle with much lower cytoplasmic free calcium concentrations, indicating an alternative mechanism has developed for fulfilling the intracellular calcium req...
112 CitationsSource
High-voltage-activated (HVA) calcium channels are known to be the primary source of calcium for glucose-stimulated insulin secretion. However, few studies have investigated how these channels can be regulated by chronically elevated levels of glucose. In the present study, we determined the level of expression of the four major HVA calcium channels (N-type, P/Q-type, LC-type, and LD-type) in rat pancreatic β-cells. Using quantitative real-time PCR (QRT-PCR), we found the expression of all four H...
24 CitationsSource
#1Xiangbin ZengH-Index: 5
#2Brian M. KeyserH-Index: 8
Last.Suresh C. SikkaH-Index: 44
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Introduction Nitric oxide‐cyclic guanosine monophosphate (NO‐cGMP)‐mediated relaxation of cavernosal smooth muscle during erection is accompanied by a decrease in intracellular calcium concentrations ([Ca2+]i). However, it is not known whether and how an increase in [Ca2+]i is responsible for (i) initiating smooth muscle contraction/detumescence following relaxation; and (ii) maintaining the penis in a flaccid state under nonstimulating conditions.
18 CitationsSource
#1Ming LiH-Index: 24
#2Min ZhangH-Index: 7
Last.Richard M WhitehurstH-Index: 6
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T-Type Ca 2+ Channels Are Involved in High Glucose–Induced Rat Neonatal Cardiomyocyte Proliferation
39 CitationsSource
Mibefradil is a Ca 2+ channel antagonist that inhibits both T-type and high-voltage-activated Ca 2+ channels. We previously showed that block of high-voltage-activated channels by mibefradil occurs through the production of an active metabolite by intracellular hydrolysis. In the present study, we modified the structure of mibefradil to develop a nonhydrolyzable analog, (1 S , 2 S )-2-(2-( N -[(3-benzimidazol-2-yl)propyl]- N -methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl c...
133 CitationsSource