Leah C. Byrne
University of Pittsburgh
8Publications
Publications 8
Newest
Published on Jan 10, 2018in Science Translational Medicine 16.71
Leah C. Byrne (University of Pittsburgh)
Delivery of a modified factor VIII gene leads to dramatic improvement of severe hemophilia A in human trials.
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Published on Oct 11, 2017in Science Translational Medicine 16.71
Leah C. Byrne (University of Pittsburgh)
Based on observations of the mechanism underlying target discrimination, researchers have developed highly accurate variants of CRISPR-Cas9.
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Published on Apr 26, 2017in Science Translational Medicine 16.71
Leah C. Byrne (University of Pittsburgh)
Transplanted RPE cells derived from induced pluripotent stem cells maintained vision and were well tolerated in a patient with age-related macular degeneration.
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Published on Mar 15, 2017in Science Translational Medicine 16.71
Leah C. Byrne (University of Pittsburgh)
A report of a patient treated with ex vivo lentiviral gene transfer to hematopoietic stem cells shows the promise of gene therapy for sickle cell anemia.
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Published on Jun 7, 2017in Science Translational Medicine 16.71
Leah C. Byrne (University of Pittsburgh)
A single intravitreal injection of AAV2 provides sustained delivery of anti-VEGF protein for the treatment of neovascular AMD.
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Published on Aug 30, 2017in Science Translational Medicine 16.71
Leah C. Byrne (University of Pittsburgh)
Researchers have edited the genome of human embryos to correct dominant myocardial disease.
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Published on Nov 22, 2017in Science Translational Medicine 16.71
Leah C. Byrne (University of Pittsburgh)
Transplantation of autologous transgenic stem cells resulted in near complete skin regeneration in a 7-year-old patient with severe junctional epidermolysis bullosa.
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Published on Jul 19, 2017in Science Translational Medicine 16.71
Leah C. Byrne (University of Pittsburgh)
Investigators from two teams have created personalized vaccines for the treatment of melanoma by identifying tumor-specific neoantigens.
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Co-Authors