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A. Mariani
Institut Gustave Roussy
SurgeryHyperthermic intraperitoneal chemotherapyColorectal cancerGeneral surgeryMedicine
9Publications
3H-index
56Citations
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Publications 9
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#1A. MarianiH-Index: 3
#2Maximiliano GelliH-Index: 7
Last. Diane GoéréH-Index: 39
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Background Management of limited synchronous colorectal peritoneal metastases (CRPM) is critical to outcome. Resection of the primary tumor and CRPM can be performed concurrently, followed by hyperthermic intraperitoneal chemotherapy (HIPEC) either immediately, during the same procedure (one-stage), or during a systematic second-stage procedure (two-stage).
1 CitationsSource
#1Maximiliano GelliH-Index: 7
Last. Diane GoéréH-Index: 39
view all 11 authors...
Abstract Introduction Over the last 20 years, complete cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) dramatically increased the survival of patients with colorectal peritoneal metastases (CRPM). However, despite better knowledge of the disease, around 70% of patients relapse after CRS with HIPEC. This study was designed to analyse the pattern of recurrence and the outcomes of different treatment modalities. Methods Patients relapsing after CRS plus H...
1 CitationsSource
Last. Diane GoéréH-Index: 39
view all 9 authors...
Source
#1Frédéric DumontH-Index: 26
#2A. MarianiH-Index: 3
Last. D Goéré
view all 4 authors...
#1Frédéric Dumont (Institut Gustave Roussy)H-Index: 26
#2A. Mariani (Institut Gustave Roussy)H-Index: 3
Last. Diane Goéré (Institut Gustave Roussy)H-Index: 39
view all 4 authors...
Resume La chirurgie du cancer du bas rectum a deux imperatifs ; obtenir des marges saines et limiter les sequelles fonctionnelles. La preservation ou non du sphincter est donc au centre du choix therapeutique. Des marges histologiques saines distales et circonferentielles de plus de 1 mm assurent un resultat oncologique correct. Ces marges dependent du stade TNM, du siege de la tumeur, de la reponse a la radiochimiotherapie et du type de chirurgie. La technique de resection intersphincterienne u...
Source
#1Frédéric Dumont (Institut Gustave Roussy)H-Index: 26
#2A. Mariani (Institut Gustave Roussy)H-Index: 3
Last. Diane Goéré (Institut Gustave Roussy)H-Index: 39
view all 4 authors...
Summary The two goals of surgery for lower rectal cancer surgery are to obtain clear “curative” margins and to limit post-surgical functional disorders. The question of whether or not to preserve the anal sphincter lies at the center of the therapeutic choice. Histologically, tumor-free distal and circumferential margins of >1 mm allow a favorable oncologic outcome. Whether such margins can be obtained depends of TNM staging, tumor location, response to chemoradiotherapy and type of surgical pro...
5 CitationsSource
#1Frédéric DumontH-Index: 26
#2A. MarianiH-Index: 3
Last. D Goéré
view all 4 authors...
#1Dominique EliasH-Index: 84
#2A. MarianiH-Index: 3
Last. Michel DucreuxH-Index: 83
view all 10 authors...
Background: Complete cytoreductive surgery (CCRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) is on the verge of becoming the gold standard treatment for selected patients presenting peritoneal metastases (PM) of colorectal origin. PM is scored with the peritoneal cancer index (PCI), which is the main prognostic factor. However, small bowel (SB) involvement could exert an independent prognostic impact. Aim: To define an adequate cut-off for the PCI and to appraise whether SB involveme...
39 CitationsSource
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