Petter Bjornstad
University of Colorado Denver
EndocrinologyRenal functionType 1 diabetesDiabetes mellitusMedicine
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Publications 133
#1Michal SchäferH-Index: 8
#2Petter BjornstadH-Index: 16
Last. Alex J. BarkerH-Index: 29
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#1Gautam Phadke (UND: University of North Dakota)H-Index: 3
#1Gautam M. Phadke (UND: University of North Dakota)
Last. Mariam P. Alexander (Mayo Clinic)H-Index: 11
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We report a case of a patient who developed dialysis-requiring acute kidney injury (AKI) after the use of canagliflozin. A 66-year-old man with type 2 diabetes who was recovering from left knee septic arthritis at a rehabilitation facility was admitted with oliguric AKI 5 days after starting treatment with canagliflozin, an inhibitor of sodium/glucose cotransporter 2 (SGLT2). The patient presented with hematuria, non–nephrotic-range proteinuria, and serum creatinine level of 6.8 (baseline, 1.1-1...
#1Petter BjornstadH-Index: 16
#2Edward NehusH-Index: 11
Last. Daniël H. van RaalteH-Index: 21
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Bariatric surgery, an emerging treatment for severely obese youth with and without T2D, provides marked improvement in insulin resistance, beta-cell function, and central adiposity. Further, preliminary data suggest that bariatric surgery also results in significant improvement in markers of obesity-related nephropathy and DKD, beyond that which can be achieved with current medical interventions. Yet, the mechanisms whereby bariatric surgery attenuates kidney disease remain unclear. This review ...
#1Charlotte M Mosterd (UvA: University of Amsterdam)
#2Petter Bjornstad (University of Colorado Denver)H-Index: 16
Last. Daniël H. van Raalte (UvA: University of Amsterdam)H-Index: 21
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Glucagon-like peptide (GLP)-1 receptor agonists are the cornerstone in the treatment of hyperglycemia in many people suffering from type 2 diabetes (T2D). These drugs have potent glucose-lowering actions and, additionally, lower body weight through satiety induction while reducing blood pressure and dyslipidemia. Partly through these actions, GLP-1 receptor agonism was shown to reduce cardiovascular disease (CVD) in people with T2D with previous CVD or at high-risk thereof. In these cardiovascul...
#1Anne C. Hesp (UvA: University of Amsterdam)
#2Jennifer A. Schaub (UM: University of Michigan)H-Index: 1
Last. Daniël H. van Raalte (UvA: University of Amsterdam)H-Index: 21
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Abstract Diabetic kidney disease is the most common cause of end-stage kidney disease and poses a major global health problem. Finding new, safe, and effective strategies to halt this disease has proven to be challenging. In part that is because the underlying mechanisms are complex and not fully understood. However, in recent years evidence has accumulated suggesting that chronic hypoxia may be the primary pathophysiological pathway driving diabetic kidney disease, and chronic kidney disease of...
#1Masanari KuwabaraH-Index: 12
#2Ichiro HisatomeH-Index: 37
Last. Miguel A. LanaspaH-Index: 35
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The optimal range of serum uric acid (urate) associated with the lowest risk for developing cardiometabolic diseases is unknown in a generally healthy population. This 5-year cohort study is designed to identify the optimal range of serum urate. The data were collected from 13,070 Japanese between ages 30 and 85 at the baseline (2004) from the Center for Preventive Medicine, St. Luke’s International Hospital, Tokyo. We evaluated the number of subjects (and prevalence) of those free of the follow...
1 CitationsSource
Last. Petter Bjornstad (CU: University of Colorado Boulder)H-Index: 16
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The association between increased serum urate and hypertension has been a subject of intense controversy. Extracellular uric acid drives uric acid deposition in gout, kidney stones, and possibly vascular calcification. Mendelian randomization studies, however, indicate that serum urate is likely not the causal factor in hypertension although it does increase the risk for sudden cardiac death and diabetic vascular disease. Nevertheless, experimental evidence strongly suggests that an increase in ...
#1Ebaa Al-Ozairi (Kuniv: Kuwait University)H-Index: 4
#2Christopher J. Rivard (University of Colorado Denver)H-Index: 35
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#1Petter Bjornstad (Anschutz Medical Campus)H-Index: 16
#2Edward Nehus (Cincinnati Children's Hospital Medical Center)H-Index: 11
Last. Thomas H. Inge (Anschutz Medical Campus)H-Index: 42
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Abstract Bariatric surgery improves markers of kidney health in severe obesity, yet it is unclear if kidney disease outcomes differ according to age at surgery. Therefore, we examined health effects of Roux-en-Y gastric bypass between 161 adolescents and 396 adults participating in two related but distinct studies. Primary outcomes were elevated urine albumin-to-creatinine ratio (UACR) of 30mg/g or more and hyperfiltration (an estimated glomerular filtration rate of 135 ml/min/1.73m2 or more). A...
#1Leo A. B. Joosten (Radboud University Nijmegen)H-Index: 94
#2Tania O. CrişanH-Index: 6
Last. Richard J. Johnson (University of Colorado Denver)H-Index: 118
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Asymptomatic hyperuricaemia affects ~20% of the general population in the USA, with variable rates in other countries. Historically, asymptomatic hyperuricaemia was considered a benign laboratory finding with little clinical importance in the absence of gout or kidney stones. Yet, increasing evidence suggests that asymptomatic hyperuricaemia can predict the development of hypertension, obesity, diabetes mellitus and chronic kidney disease and might contribute to disease by stimulating inflammati...
1 CitationsSource