Match!
Graham Jordan Ray
University of California, Berkeley
7Publications
4H-index
377Citations
Publications 7
Newest
Published on Jul 1, 2018in Nature43.07
Dimitre R. Simeonov12
Estimated H-index: 12
,
Benjamin G. Gowen7
Estimated H-index: 7
(University of California, Berkeley)
+ 35 AuthorsAlice Y. Chan11
Estimated H-index: 11
(UCSF: University of California, San Francisco)
In this Letter, analysis of steady-state regulatory T (Treg) cell percentages from Il2ra enhancer deletion (EDEL) and wild-type (WT) mice revealed no differences between them (Extended Data Fig. 9d). This analysis included two mice whose genotypes were incorrectly assigned. Even after correction of the genotypes, no significant differences in Treg cell percentages were seen when data across experimental cohorts were averaged (as was done in Extended Data Fig. 9d). However, if we normalize the co...
Published on Sep 1, 2017in Nature43.07
Dimitre R. Simeonov12
Estimated H-index: 12
,
Benjamin G. Gowen7
Estimated H-index: 7
+ 35 AuthorsAlice Y. Chan11
Estimated H-index: 11
The authors use tiled CRISPR activation for functional enhancer discovery across two autoimmunity risk loci, CD69 and IL2RA, and identify elements with features of stimulus-responsive enhancers, including an IL2RA enhancer that harbours a fine-mapped autoimmunity risk variant.
Published on Jan 11, 2017
Jacob E. Corn29
Estimated H-index: 29
,
Christopher D. Richardson3
Estimated H-index: 3
,
Graham Jordan Ray4
Estimated H-index: 4
La presente invention concerne des procedes et des compositions destines a ameliorer l'edition de l'ADN d'un genome. Par exemple, dans certains modes de realisation, la presente invention concerne un procede d'edition de l'ADN d'un genome d'une cellule eucaryote, le procede consistant a introduire dans une cellule eucaryote une composition comprenant : (a) une composition d'ADN non homologue linearise et (b) une composition ciblant le genome (comprenant une endonuclease editant le genome ou un a...
Published on Dec 5, 2016in bioRxiv
Dimitre R. Simeonov12
Estimated H-index: 12
(UCSF: University of California, San Francisco),
Benjamin G. Gowen7
Estimated H-index: 7
(University of California, Berkeley)
+ 22 AuthorsJonathan M. Woo8
Estimated H-index: 8
(UCSF: University of California, San Francisco)
The majority of genetic variants associated with common human diseases map to enhancers, non-coding elements that shape cell type-specific transcriptional programs and responses to specific extracellular cues1-3. In order to understand the mechanisms by which non-coding genetic variation contributes to disease, systematic mapping of functional enhancers and their biological contexts is required. Here, we develop an unbiased discovery platform that can identify enhancers for a target gene without...
Published on Mar 1, 2016in Nature Biotechnology31.86
Christopher D. Richardson27
Estimated H-index: 27
,
Graham Jordan Ray4
Estimated H-index: 4
+ 2 AuthorsJacob E. Corn29
Estimated H-index: 29
The efficiency of homology-directed genome editing with CRISPR-Cas9 is boosted through improved design of donor DNA.
1