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Vera Paar
University of Salzburg
33Publications
4H-index
65Citations
Publications 33
Newest
#1Moritz MirnaH-Index: 2
#2Vera PaarH-Index: 4
Last.Christian JungH-Index: 45
view all 8 authors...
Background: MicroRNAs (miRNAs) are small, single-stranded RNA sequences that regulate gene expression on a post-transcriptional level. In the last few decades, various trials have investigated the diagnostic and therapeutic potential of miRNAs in several disease entities. Here, we provide a review of the available evidence on miRNAs in inflammatory heart diseases (myocarditis, endocarditis, and pericarditis) and sepsis-induced cardiac dysfunction. Methods: Systematic database research using the ...
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Cardiac arrhythmias constitute a major health problem with a huge impact on mortality rates and health care costs. Despite ongoing research efforts, the understanding of the molecular mechanisms and processes responsible for arrhythmogenesis remains incomplete. Given the crucial role of Ca2+-handling in action potential generation and cardiac contraction, Ca2+ channels and Ca2+ handling proteins represent promising targets for suppression of ventricular arrhythmias. Accordingly, we report the di...
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#1Peter JirakH-Index: 3
#2Michael LichtenauerH-Index: 15
Last.Rudin PistulliH-Index: 7
view all 10 authors...
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#1Moritz Mirna (University of Salzburg)H-Index: 2
#2Vera Paar (University of Salzburg)H-Index: 4
Last.Michael Lichtenauer (University of Salzburg)H-Index: 15
view all 8 authors...
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#1Christoph Edlinger (University of Salzburg)H-Index: 2
#2Vera Paar (University of Salzburg)H-Index: 4
Last.Michael Lichtenauer (University of Salzburg)H-Index: 15
view all 12 authors...
Abstract Background Leadless pacemaker technology is a promising upcoming field in clinical rhythmology. Today, the most commonly used system in the clinical setting is the Micra™ leadless pacemaker system (Medtronic). In autopsies of patients who witnessed non-pacemaker associated death, unexpected ingrowth/encapsulation within the wall of the right ventricle was reported. The occurrence of a complete encapsulation was not expected and the process of endothelialisation remains unclear. We hypot...
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#1Daniel DalosH-Index: 6
#2Georg SpinkaH-Index: 1
Last.Michael SponderH-Index: 6
view all 9 authors...
Background: Various biomarkers have been associated with coronary artery disease (CAD) and ischemic heart failure. The aim of this study was to investigate the correlation of serum levels of soluble urokinase-type plasminogen activator receptor (suPAR), growth differentiation factor 15 (GDF-15), heart-type fatty acid-binding protein (H-FABP), and soluble suppression of tumorigenicity 2 (sST2) with left ventricular ejection fraction (EF) in CAD patients and controls. Methods and Results: CAD pati...
2 CitationsSource
#1Michael Sponder (Medical University of Vienna)H-Index: 6
#2Michael Lichtenauer (University of Salzburg)H-Index: 15
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The aim of this prospective study was to investigate the influence of long-term physical activity on biomarkers for myocyte ischemia (heart-type fatty acid-binding protein, H-FABP), matrix remodelling/vascular stress (soluble isoform of suppression of tumorigenicity 2, sST2) and inflammation (soluble urokinase-type plasminogen activator receptor, suPAR). In this prospective observational study 109 subjects were recruited, 98 completed the study. Subjects were asked to perform exercise within the...
1 CitationsSource
#1Christoph Edlinger (University of Salzburg)H-Index: 2
#2Michael Lichtenauer (University of Salzburg)H-Index: 15
Last.Daniel Kretzschmar (FSU: University of Jena)H-Index: 8
view all 13 authors...
Peripheral arterial disease (PAD) is one of the most common manifestations of systemic atherosclerosis. The prevalence of unrecognized PAD is high, leading to a lack of opportunity to detect subjects at a high risk for cardiovascular events. Inflammatory processes play an important role in the disease initiation as well as in the disease progression. Vascular cell adhesion molecule 1 (VCAM-1), a biomarker of endothelial dysfunction, appears to be an important mediator in inflammatory processes. ...
2 CitationsSource
#1Moritz Mirna (University of Salzburg)H-Index: 2
#2Ilonka Rohm (FSU: University of Jena)H-Index: 7
Last.Marcus Franz (FSU: University of Jena)H-Index: 16
view all 12 authors...
Background Due to the non-specific clinical presentation of patients with pulmonary hypertension (PH), diagnosis is often delayed, consequently resulting in limited therapeutic success and an impaired prognosis. In this trial, we analysed the plasma concentrations of novel cardiovascular biomarkers that reflect different pathobiological pathways (sST2: soluble suppression of tumorigenicity 2, H-FABP: heart type fatty acid binding protein, suPAR: soluble urokinase plasminogen activator receptor a...
1 CitationsSource
#1Johanna MuessigH-Index: 4
#2Michael Lichtenauer (University of Salzburg)H-Index: 15
Last.Christian JungH-Index: 45
view all 15 authors...
Abstract Introduction Severe aortic stenosis (AS) caused by degenerative calcification is the most frequent acquired valvular heart disease worldwide and mortality rates are considerably high. Transcatheter Aortic Valve Implantation (TAVI) is a well-established method for valve replacement in high risk patients with AS. However, there is a lack of reliable predictors for patients undergoing TAVI since commonly used scores were developed for surgical populations. Materials and methods 208 patient...
2 CitationsSource
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