Aulikki Nissinen
University of Eastern Finland
Publications 97
#1Amery A (Katholieke Universiteit Leuven)H-Index: 52
#2K. BeardH-Index: 3
Last.Willemse PH-Index: 5
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792 hypertensive patients above the age of 60 have entered the double-blind multicentre trial of the European Working Party on High blood pressure in the Elderly (EWPHE). Half were treated with hydrochlorothiazide and triamterene and half were given placebo and a second capsule was given and if necessary up to 2 g of methyldopa/day. The measurements in a sample of 157 patients suggested 80–86% compliance rate. A significant blood pressure difference of 25/10 mm Hg was obtained between the groups...
1 CitationsSource
#1Pekka PuskaH-Index: 64
#2Jaakko TuomilehtoH-Index: 185
Last.Jukka T. SalonenH-Index: 76
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1 CitationsSource
#1Aulikki NissinenH-Index: 42
#2Jaakko TuomilehtoH-Index: 185
Last.Elo JH-Index: 3
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1 CitationsSource
#1Jaakko Tuomilehto (University of Eastern Finland)H-Index: 185
#2Pekka Puska (University of Eastern Finland)H-Index: 6
Last.Virtamo J (University of Eastern Finland)H-Index: 5
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1 CitationsSource
#1Aulikki Nissinen (University of Eastern Finland)H-Index: 42
#2Jaakko Tuomilehto (University of Eastern Finland)H-Index: 185
Last.Pekka Puska (University of Eastern Finland)H-Index: 6
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1 CitationsSource
#1Jari H. StengårdH-Index: 25
#2Juha PekkanenH-Index: 87
Last.Aulikki Nissinen (University of Eastern Finland)H-Index: 42
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An association between late-onset Alzheimer's disease, vascular dementia and the common polymorphic alleles of the gene coding for apolipoprotein E, ɛ2, ɛ3 and ɛ4, was assessed in a population sample of 393 elderly Finnish men aged 70 to 89 years. Of them, 7%, suffered Alzheimer's disease and 3% had vascular dementia. Among those who suffered Alzheimer's disease, there was a statistically significant excess of the ɛ4 allele. No such an association was observed between the apolipoprotein E allele...
32 CitationsSource
#2Mirjam I. GeerlingsH-Index: 49
Last.Daan KromhoutH-Index: 8
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Background: Depression is associated with an increased risk of cardiovascular diseases (CVD) and cardiovascular mortality. We investigated to what extent subjective health status explained the apparent association between depressive symptoms and cardiovascular mortality in older European men. Methods: Data were used from the population-based prospective Finland, Italy and the Netherlands Elderly (FINE) Study. Depressive symptoms were measured with the Zung Self-rating Depression Scale in 909 men...
The authors aimed to quantify the effects of current systolic blood pressure (SBP) and serum total cholesterol on the risk of mortality in comparison with SBP or serum cholesterol 25 years previously, taking measurement error into account. The authors reanalyzed 35-year follow-up data on mortality due to coronary heart disease and stroke among subjects aged 65 years or more from nine cohorts of the Seven Countries Study. The two-step method of Tsiatis et al. (J Am Stat Assoc 1995;90:27-37) was u...