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Dajeong Kim
Seoul National University
11Publications
3H-index
17Citations
Publications 11
Newest
#1Hyejin Kim (SNU: Seoul National University)H-Index: 23
#2Dajeong Kim (SNU: Seoul National University)H-Index: 3
Last.Jong Bum Lee (SNU: Seoul National University)H-Index: 18
view all 6 authors...
Abstract Cells secrete extracellular vesicles (EVs) to external environments to achieve cellular homeostasis and cell-to-cell communication. Their therapeutic potential has been constantly spotlighted since they mirror both cytoplasmic and membranous components of parental cells. Meanwhile, growing evidence suggests that EV engineering could further promote EVs with a maximized capacity. In this review, a range of engineering techniques as well as upscaling approaches to exploit EVs and their mi...
1 CitationsSource
#1Daheui Choi (Yonsei University)H-Index: 8
#2Hyejin Kim (SNU: Seoul National University)H-Index: 23
Last.Jinkee Hong (Yonsei University)H-Index: 20
view all 7 authors...
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#1Dajeong Kim (SNU: Seoul National University)H-Index: 3
#2Hyejin Kim (SNU: Seoul National University)H-Index: 1
Last.Jong Bum Lee (SNU: Seoul National University)H-Index: 18
view all 6 authors...
Source
#1Dajeong Kim (SNU: Seoul National University)H-Index: 3
#2Hyejin Kim (SNU: Seoul National University)H-Index: 1
Last.Jong Bum Lee (SNU: Seoul National University)H-Index: 3
view all 6 authors...
1 CitationsSource
#1Heejung Jung (Konkuk University)H-Index: 2
#2Dajeong Kim (SNU: Seoul National University)H-Index: 3
Last.Hyejung Mok (Konkuk University)H-Index: 17
view all 6 authors...
Correction for ‘CpG incorporated DNA microparticles for elevated immune stimulation for antigen presenting cells’ by Heejung Jung et al., RSC Adv., 2018, 8, 6608–6615.
Source
#1Hyejin KimH-Index: 23
#2Dajeong KimH-Index: 3
Last.Jong LeeH-Index: 1
view all 5 authors...
Thanks to a wide range of biological functions of RNA, and advancements in nanotechnology, RNA nanotechnology has developed in multiple ways for RNA-based therapeutics. In particular, among RNA engineering techniques, enzymatic self-assembly of RNA structures has gained great attention for its high packing density of RNA, with a low cost and one-pot synthetic process. However, manipulation of the overall size of particles, especially a reduction in size, has not been studied in depth. Here, we r...
1 CitationsSource
#1Heejung Jung (Konkuk University)H-Index: 2
#2Dajeong Kim (SNU: Seoul National University)H-Index: 3
Last.Hyejung Mok (Konkuk University)H-Index: 17
view all 6 authors...
As emerging evidence supports the immune stimulating capability of the CpG oligodeoxynucleotides (ODN), CpG-based adjuvants have been widely used. For efficient induction of immune responses, current issues affecting the use of nucleic acid-based adjuvants, e.g. stability in physiological conditions, delivery to immune cells, and successful release within the phagolysosome, should be addressed. Here, we present CpG-based DNA microparticles (DNA-MPs) fabricated by complementary rolling circle amp...
3 CitationsSource
#1Hyejin Kim (SNU: Seoul National University)H-Index: 23
#2Jaepil Jeong (SNU: Seoul National University)H-Index: 4
Last.Jong Bum Lee (SNU: Seoul National University)H-Index: 18
view all 6 authors...
As ribonucleic acid (RNA) nanotechnology has advanced, it has been applied widely in RNA-based therapeutics. Among the range of approaches, enzymatically synthesized RNA structures for inducing RNA interference in cancer cells have potential for silencing genes in a target-specific manner. On the other hand, the efficiency of gene silencing needs to be improved to utilize the RNA-based system for RNAi therapeutics. This paper introduces a new approach for efficient generation of siRNA from bubbl...
6 CitationsSource
#1Joseph T Long (UW: University of Washington)H-Index: 1
#2Hyejin Kim (SNU: Seoul National University)H-Index: 23
Last.Deok-Ho Kim (UW: University of Washington)H-Index: 41
view all 5 authors...
The cell reprogramming of somatic cells into pluripotent states and subsequent differentiation into certain phenotypes has helped progress regenerative medicine research and other medical applications. Recent research has used viral vectors to induce this reprogramming; however, limitations include low efficiency and safety concerns. In this review, we discuss how biomaterial methods offer potential avenues for either increasing viability and downstream applicability of viral methods, or providi...
4 CitationsSource
#1Ji-Eun Kim (SNU: Seoul National University)H-Index: 33
#2Dajeong Kim (SNU: Seoul National University)H-Index: 3
Last.Jong Bum Lee (SNU: Seoul National University)H-Index: 3
view all 3 authors...
Here, we synthesized DNA microparticles comprised of thrombin binding aptamers via rolling circle amplification (RCA). These DNA aptamer particles could successfully load a number of thrombins and the complexes have shown improved thrombin activity. This new platform offers a protein loading and delivery system for medical applications.
2 CitationsSource
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