Michal Cohen
Rambam Health Care Campus
Quality of lifeEndocrinologyCraniopharyngiomaDiabetes mellitusMedicine
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Publications 9
#1Michal Cohen (Rambam Health Care Campus)H-Index: 5
#2Meirav Oren (Rambam Health Care Campus)
Last. Naim Shehadeh (Rambam Health Care Campus)H-Index: 23
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#1Ruth Livny (Rambam Health Care Campus)
#2Wasim Said (Rambam Health Care Campus)H-Index: 1
Last. Michal CohenH-Index: 1
view all 11 authors...
OBJECTIVES: Reports suggest that children with type 1 diabetes (T1D) perform less than the recommended daily activity and are less active than their non-diabetic peers. We aimed to: (a) Identify barriers and sources of support for exercise performance in pediatric T1D. (b) Identify strengths and limitations in the exercise-directed education provided by our diabetes team. METHODS: Patients with T1D 5 to 20 years of age were recruited while attending a routine clinic visit. Participants completed...
#1Michal Cohen (Rappaport Faculty of Medicine)H-Index: 5
#2Rebecca Persky (NIH: National Institutes of Health)H-Index: 2
Last. Dov Tiosano (Rappaport Faculty of Medicine)H-Index: 23
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BACKGROUND: Somatic mutations in the ubiquitin-specific peptidase 8 (USP8) gene are common in corticotropinomas of children with Cushing disease (CD). We report a unique patient with a germline USP8 mutation who presented with CD and a constellation of other findings that constitute an intriguing genetic syndrome. CASE DESCRIPTION: We describe a 16-year-old female with CD, developmental delay, dysmorphic features, ichthyosiform hyperkeratosis, chronic lung disease, chronic kidney disease, hyperg...
1 CitationsSource
#2Wasim SaidH-Index: 1
Last. Michal CohenH-Index: 1
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#1Michal CohenH-Index: 1
#2Smadar ShiloH-Index: 1
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#1Michal CohenH-Index: 5
#2Ute BartelsH-Index: 36
Last. HamiltonJillH-Index: 32
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Background. Craniopharyngioma tumors and their treatment can lead to significant long-term morbidity due to their proximity to vital structures. The optimal treatment has been debated for many years. We aimed to review the long-term outcomes of children treated for craniopharyngioma in our institution over the past decade and describe trends in treatment and outcomes over the past 3 decades. Methods. Charts of children with craniopharyngioma treated and followed at The Hospital for Sick Children...
50 CitationsSource
#1Michal CohenH-Index: 5
#2Catriona SymeH-Index: 15
Last. HamiltonJillH-Index: 32
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Objective: Dysregulation of the autonomic nervous system is thought to be involved in craniopharyngioma-related hypothalamic obesity (CRHO). Increased parasympathetic activity and decreased sympathetic activity have been suggested. We aimed to study autonomic activity using heart rate variability (HRV) and biochemical measures in youth with CRHO compared with controls and to explore relationships between obesity and autonomic indices. Design: A cross-sectional study of 16 youth with CRHO and 16 ...
14 CitationsSource
#1Charles F. Verge (UNSW: University of New South Wales)H-Index: 30
#2Daniel Konrad (Boston Children's Hospital)H-Index: 25
Last. Samuel Refetoff (U of C: University of Chicago)H-Index: 80
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Context: Monocarboxylate transporter 8 (MCT8) is a thyroid hormone-specific cell membrane transporter. MCT8 deficiency causes severe psychomotor retardation and abnormal thyroid tests. The great majority of affected children cannot walk or talk, and all have elevated serum T3 levels, causing peripheral tissue hypermetabolism and inability to maintain weight. Treatment with thyroid hormone is ineffective. In Mct8-deficient mice, the thyroid hormone analog, diiodothyropropionic acid (DITPA), does ...
73 CitationsSource
#1Michal CohenH-Index: 5
#2Sharon GugerH-Index: 8
Last. HamiltonJillH-Index: 32
view all 3 authors...
Craniopharyngioma are rare histologically benign brain tumors that develop in the pituitary- hypothalamic area. They may invade nearby anatomical structures causing significant rates of neurological, neurocognitive and endocrinological complications including remarkable hypothalamic damage. Information regarding long term implications of the tumors and treatment in the pediatric population is accumulating, and treatment goals appear to be changing accordingly. In this review we aim to present da...
22 CitationsSource