Yi Cai
Yantai University
Crystal structureChemistryChrysinStackingOrthorhombic crystal system
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Publications 2
#1Xinli Li (Yantai University)H-Index: 1
#2Yi Cai (Yantai University)H-Index: 2
Last. Qing-Guo Meng (Yantai University)H-Index: 3
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In order to search for drugs with excellent antibacterial activities, a series of novel chrysin derivatives were designed, synthesized, and evaluated as antibacterial agents. Results of the preliminary antibacterial tests against six human pathogenic bacteria in vitro showed that these compounds exhibited activities to some extent, and some displayed excellent activities than the natural parent chrysin, while some were even more potent than the positive drug Penicillin. Moreover, the molecular m...
3 CitationsSource
#1Qing-Guo Meng (Yantai University)H-Index: 3
#2Wen-Juan Tan (Yantai University)H-Index: 1
Last. Yi Bi (Yantai University)H-Index: 1
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Abstract Two epimers, 20S,24R-epoxy dammarane-3β,12β,25-triol (3) and 20S,24S-epoxy dammarane-3β,12β,25-triol (4) were prepared from 20(S)-protopanaxadiol, which were confirmed by ESI-MS, NMR, and X-ray single-crystal diffraction. The results indicate the configuration of C-24 of 3 and 4 are R-form and S-form, respectively. 3 and 4 crystallize in a orthorhombic space group P2(1)2(1)2(1). Compound 3 have more complicated intramolecular hydrogen bonds than that of 4, which results in the weaker mo...
7 CitationsSource