Laura Chambre
Boğaziçi University
CopolymerChemistryEthylene glycolMaleimideThiol
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Publications 3
#1Laura Chambre (Boğaziçi University)H-Index: 2
#2Wen Shang SawH-Index: 3
Last. Amitav Sanyal (Boğaziçi University)H-Index: 25
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Photosensitizing nanogels were obtained through a surfactant-free single-step protocol by using a porphyrin-based cross-linker for stabilizing self-assembled nanosized aggregates of thermoresponsive copolymers. Nanogels with varying amounts of porphyrin retained the singlet oxygen generation ability of the porphyrin core and were also capable of inducing temperature increase upon irradiation at 635 nm. Photoinduced killing efficiency was tested against three cell lines: human breast adenocarcino...
1 CitationsSource
#1Laura ChambreH-Index: 2
#2Aysun DegirmenciH-Index: 2
Last. Amitav SanyalH-Index: 25
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Nanogels that are amenable to facile multi-functionalization with imaging, therapeutic, and targeting agents are attractive theranostic platforms for addressing challenges in conventional diagnostics and therapy. In this work, reactive copolymers containing poly(ethylene glycol), maleimide, and pendant hydroxyl groups as side chains are used to construct nanogels by employing their thermoresponsive self-assembly in aqueous media. Subsequent cross-linking of these nanosized aggregates with dithio...
8 CitationsSource
#1Bugra AktanH-Index: 1
#2Laura ChambreH-Index: 2
Last. Amitav SanyalH-Index: 25
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Multifunctionalizable nanogels are fabricated using thermally driven self-assembly and cross-linking of reactive thermoresponsive copolymers. Nanogels thus fabricated can be easily conjugated with various appropriately functionalized small molecules and/or ligands to tailor them for various applications in delivery and imaging. In this study, a poly(ethylene glycol)-methacrylate-based maleimide-bearing copolymer was cross-linked with a dithiol-based cross-linker to synthesize nanogels. Because o...
9 CitationsSource