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Huifang Ge
Fujian Agriculture and Forestry University
ChemistryAntioxidantTetramethylpyrazineChromatographyBiochemistry
4Publications
3H-index
21Citations
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Publications 5
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#1Huifang Ge (Fujian Agriculture and Forestry University)H-Index: 3
#2Peixuan Lin (Fujian Agriculture and Forestry University)
Last. Jicheng Chen (Fujian Agriculture and Forestry University)H-Index: 3
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Abstract Ligusticum chuanxiong extract-polylactic acid sustained-release microspheres (LCE-PLA) are fabricated in this study for enhancing both duration and hepatoprotective efficacy of the main bioactive ingredients. LCE-PLA in vitro release, cytotoxicity and in vivo hepatoprotective effect were discussed to evaluate its efficiency and functionality. Results demonstrated that the optimal drug-loading rate and encapsulation efficiency of tetramethylpyrazine (TMP, the main active ingredient) were...
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#1Jicheng Chen (Fujian Agriculture and Forestry University)H-Index: 3
#2Yazhen Chen (Fujian Agriculture and Forestry University)H-Index: 2
Last. Song Miao (Fujian Agriculture and Forestry University)H-Index: 20
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Abstract The hierarchical structure, pasting and digestibility of adlay seed starch (ASS) were investigated compared with maize starch (MS) and potato starch (PS). ASS exhibited round or polyglonal morphology with apparent pores/channels on the surface. It had a lower amylose content, a looser and more heterogeneous C-type crystalline structure, a higher crystallinity, and a thinner crystalline lamellae. Accordingly, ASS showed a higher slowly digestible starch content combined with less resista...
2 CitationsSource
#1Jicheng Chen (Fujian Agriculture and Forestry University)H-Index: 3
#2Yazhen Chen (Fujian Agriculture and Forestry University)H-Index: 2
Last. Hetong Lin (Fujian Agriculture and Forestry University)H-Index: 19
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Abstract A simple, accurate and specific high-performance liquid chromatography (HPLC) method has been developed and validated for simultaneous determination of sesamol, sesamin, asarinin and sesamolin in Monascus aged vinegar. The effects of acid hydrolysis and four heating treatments on the components content in Monascus aged vinegar were discussed. The results showed that the isomerisation of sesamin to asarinin, and decomposition of sesamolin to sesamol significantly increased, regardless of...
6 CitationsSource
#1Huifang Ge (Fujian Agriculture and Forestry University)H-Index: 3
#2Yazhen Chen (Fujian Agriculture and Forestry University)H-Index: 2
Last. Lei Chen (Fujian Agriculture and Forestry University)H-Index: 10
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Abstract The Rhizome of Ligusticum chuanxiong Hort, a traditional Chinese medicine, is widely used to treat cardiovascular diseases and attenuate oxidative stress. The main bioactive compounds including tetramethylpyrazine (TMP), polyphenols, ferulic acid have been reported to be responsible for these effects. This study was to evaluate the influence of Ligusticum chuanxiong extraction (LCE) in mimic gastrointestinal tract on antioxidant activity. The effects of gastric digestion group metabolic...
3 CitationsSource
#1Jicheng Chen (Cornell University)H-Index: 1
#2Jingjing TianH-Index: 3
Last. Jianbo Xiao (UM: University of Macau)H-Index: 36
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Abstract Tetramethylpyrazine is a bioactive compound found in Chinese black vinegar. This work is to investigate the potential effects of tetramethylpyrazine on intracellular cholesterol modulation in HepG2 cells. The results demonstrated that tetramethylpyrazine can induce intracellular cholesterol efflux. Tetramethylpyrazine may also improve endothelial function through its antioxidant effects by inhibiting reactive oxygen species levels and increasing the antioxidant enzymes superoxide dismut...
10 CitationsSource
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