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Biljana Petrovic
University of Bologna
VirologyReceptorOncolytic virusBiologyCancer cell
11Publications
5H-index
72Citations
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Publications 12
Newest
#1Emanuele SassoH-Index: 4
Last. Elisa ScarselliH-Index: 20
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Oncolytic virotherapy is emerging as a promising therapeutic option for solid tumours. Several oncolytic vectors in clinical testing are based on attenuated viruses; thus, efforts are being taken to develop a new repertoire of oncolytic viruses, based on virulent viral genomes. This possibility, however, raises concerns dealing with the safety features of the virulent phenotypes. We generated a double regulated Herpes simplex type-1 virus (HSV-1), in which tumour cell restricted replicative pote...
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#1Laura MenottiH-Index: 17
#2Valerio LeoniH-Index: 8
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#1Andrea VanniniH-Index: 7
#2Biljana PetrovicH-Index: 5
Last. Tatiana GianniH-Index: 15
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#1Laura Menotti (UNIBO: University of Bologna)H-Index: 17
#2Elisa Avitabile (UNIBO: University of Bologna)H-Index: 21
Last. Gabriella Campadelli-Fiume (UNIBO: University of Bologna)H-Index: 41
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Previously, we engineered oncolytic herpes simplex viruses (o-HSVs) retargeted to the HER2 (epidermal growth factor receptor 2) tumor cell specific receptor by the insertion of a single chain antibody (scFv) to HER2 in gD, gH, or gB. Here, the insertion of scFvs to three additional cancer targets—EGFR (epidermal growth factor receptor), EGFRvIII, and PSMA (prostate specific membrane antigen)—in gD Δ6–38 enabled the generation of specifically retargeted o-HSVs. Viable recombinants resulted from t...
5 CitationsSource
#1Valerio LeoniH-Index: 8
#2Biljana PetrovicH-Index: 5
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3 CitationsSource
#1Biljana PetrovicH-Index: 5
#2Valerio LeoniH-Index: 8
view all 6 authors...
4 CitationsSource
#1Valerio Leoni (UNIBO: University of Bologna)H-Index: 8
#2Biljana Petrovic (UNIBO: University of Bologna)H-Index: 5
Last. Gabriella Campadelli-Fiume (UNIBO: University of Bologna)H-Index: 41
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1 CitationsSource
#1Biljana PetrovicH-Index: 5
#2Valerio LeoniH-Index: 8
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3 CitationsSource
#1Valerio Leoni (UNIBO: University of Bologna)H-Index: 8
#2Valentina Gatta (UNIBO: University of Bologna)H-Index: 4
Last. Gabriella Campadelli-Fiume (UNIBO: University of Bologna)H-Index: 41
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7 CitationsSource
#1Biljana Petrovic (UNIBO: University of Bologna)H-Index: 5
#2Tatiana Gianni (UNIBO: University of Bologna)H-Index: 15
Last. Gabriella Campadelli-Fiume (UNIBO: University of Bologna)H-Index: 41
view all 4 authors...
15 CitationsSource
12