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Italo Rodrigo Calori
University of São Paulo
Quenching (fluorescence)ChemistryPhotosensitizerPhotochemistryFluorescence
5Publications
2H-index
9Citations
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Publications 9
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#1Italo Rodrigo Calori (USP: University of São Paulo)H-Index: 2
Last. Antonio Claudio TedescoH-Index: 37
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Abstract Up-regulated monocarboxylate transporters (MCTs) serve as potential targets for the development of novel therapeutic strategies against some cancer cells. Besides being an efficient substrate to some MCTs, the role of alpha-cyano-4-hydroxycinnamic acid (CHCA) as a vector of nanoparticles for cancer cells was not yet evaluated. This aim of this study was to demonstrate the role of CHCA as a vector of liposomes targeting cancer cells that overexpress MCT-1. Also, the antioxidant character...
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Last. Noboru HiokaH-Index: 20
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Over the past decade, hypericin (Hy) has been used by several researchers due to its broad therapeutic potential against microorganisms and cancer cells. Considering the high hydrophobicity of Hy, ...
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#1Italo Rodrigo Calori (USP: University of São Paulo)H-Index: 2
#2Gustavo BragaH-Index: 4
Last. Antonio Claudio Tedesco (USP: University of São Paulo)H-Index: 37
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Abstract Drug delivery scaffolds are smart alternatives to conventional formulations and allow for controlled spatiotemporal releases of active compounds. In several fields of human health, various methods have emerged with natural and synthetic polymers that make the fabrication of new polymer scaffolds possible. This review provides an overview of all recently published studies on the development and application of polymer scaffolds targeting controlled drug delivery in medicinal fields, inclu...
1 CitationsSource
#1Italo Rodrigo Calori (USP: University of São Paulo)H-Index: 2
Last. Noboru HiokaH-Index: 20
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Abstract Stealth strategies have improved some properties of drug nanocarriers, including circulation time in vivo and kinetic stability, which led to the novel-generation of stealth liposomes. Among these, Pluronic®/lipid mixtures provide one of the simplest and lowest-cost stealth liposomes, although the formation of Pluronic micelles above its critical micelle temperature (CMT) concurrently lead to undesirable effects in a drug-carrier approach. Recently, we proposed a fluorometric method to ...
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#1Italo Rodrigo Calori (USP: University of São Paulo)H-Index: 2
#2Antonio Claudio Tedesco (USP: University of São Paulo)H-Index: 37
Abstract Current limited understanding of the intracellular self-aggregation process of several photosensitizers is one of the obstacles in the progress of Photodynamic Therapy (PDT) as a clinically viable option to photomodulate the biological responses. This is further intensified by the higher in vitro experimental complexity as compared to the experiments carried out in simple solution. This study describes the monomer(photoactive)/aggregate(non-active) equilibrium of aluminum chloride phtha...
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#1Italo Rodrigo Calori (USP: University of São Paulo)H-Index: 2
#2Wallance Moreira Pazin (USP: University of São Paulo)H-Index: 7
Last. Noboru HiokaH-Index: 20
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Abstract Future-generation liposomes for efficient drug-delivery systems may utilize multifunctional polymer coatings for stabilization and in order to take advantage of conferred properties such as stealth characteristics. In this scenario, understanding the dynamics of polymers coating liposomes versus polymers self-assembly as micelles is a critical issue. This paper describes a methodology to determinate the boundary between the presence of only liposomes and the coexistence of liposomes and...
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#1Italo Rodrigo Calori (USP: University of São Paulo)H-Index: 2
#2Cristiano Ceron Jayme (USP: University of São Paulo)H-Index: 2
Last. Antonio Claudio Tedesco (USP: University of São Paulo)H-Index: 37
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Abstract Monomeric zinc phthalocyanine has been studied as a promising active photosensitizer in photodynamic therapy against cancer, in which its aggregate form is non-active. This paper aimed to describe the monomer/aggregates equilibrium of zinc phthalocyanine in binary water/DMSO mixtures. To reach this aim theoretical calculation, electronic absorption, static and time-resolved fluorescence, and resonance light scattering was used. Zinc phthalocyanine shows a complex water dependence behavi...
1 CitationsSource
#1Cristiano Ceron Jayme (USP: University of São Paulo)H-Index: 2
#2Leonardo Barcelos de Paula (USP: University of São Paulo)H-Index: 5
Last. Antonio Claudio Tedesco (USP: University of São Paulo)H-Index: 37
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Abstract DNA polymeric films (DNA-PFs) are a promising drug delivery system (DDS) in modern medicine. In this study, we evaluated the growth behavior of oral squamous cell carcinoma (OSCC) cells on DNA-PFs. The morphological, biochemical, and cytometric features of OSCC cell adhesion on DNA-PFs were also assessed. An initial, temporary alteration in cell morphology was observed at early time points owing to the inhibition of cell attachment to the film, which then returned to a normal morphologi...
2 CitationsSource
#1Italo Rodrigo Calori (USP: University of São Paulo)H-Index: 2
#2Diogo Silva Pellosi (UEM: Universidade Estadual de Maringá)H-Index: 12
Last. Wilker Caetano (UEM: Universidade Estadual de Maringá)H-Index: 20
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The correct selection of a dye that has effective action as a photosensitizer is a primary concern for successful therapeutic outcomes. The effectiveness of the photodynamic agent is related to both the targeting of cell membranes and the photochemical yield of the chosen dye. The distributions of xanthene derivatives Eosin Y, Erythrosin B, and Rose Bengal B in vesicles of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) in both liquid-crystalline and gel phases were investigated by fluorescen...
6 CitationsSource
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