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Peter N. Taylor
Cardiff University
61Publications
13H-index
642Citations
Publications 61
Newest
Published on Jan 1, 2019in International Journal of Molecular Sciences 4.18
Nicholas Wilson , Robert Steadman28
Estimated H-index: 28
+ 6 AuthorsLei Zhang11
Estimated H-index: 11
Hyaluronan (HA), an extra-cellular matrix glycosaminoglycan, may play a role in mesenchymal stem cell differentiation to fat but results using murine models and cell lines are conflicting. Our previous data, illustrating decreased HA production during human adipogenesis, suggested an inhibitory role. We have investigated the role of HA in adipogenesis and fat accumulation using human primary subcutaneous preadipocyte/fibroblasts (PFs, n = 12) and subjects of varying body mass index (BMI). The im...
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Published on Apr 1, 2019in The Lancet Diabetes & Endocrinology 24.54
Onyebuchi E. Okosieme16
Estimated H-index: 16
(Cardiff University),
Peter N. Taylor13
Estimated H-index: 13
(Cardiff University)
+ 11 AuthorsAdrian Sayers20
Estimated H-index: 20
(UoB: University of Bristol)
Summary Background Graves' disease is routinely treated with antithyroid drugs, radioiodine, or surgery, but whether the choice of initial therapy influences long-term outcomes is uncertain. We evaluated cardiovascular morbidity and mortality according to the method and effectiveness of primary therapy in Graves' disease. Methods In this retrospective cohort study, we identified patients with hyperthyroidism, diagnosed between Jan 1, 1998, and Dec 31, 2013, from a thyroid-stimulating hormone (TS...
1 Citations Source Cite
Published on Feb 1, 2019in Thyroid 7.79
Salman Razvi21
Estimated H-index: 21
(Newcastle University),
Tim I. M. Korevaar14
Estimated H-index: 14
(EUR: Erasmus University Rotterdam),
Peter N. Taylor13
Estimated H-index: 13
(Cardiff University)
Background: Recent reports suggest that prescriptions for thyroid hormones have increased. Recent trends in and determinants of the prevalence of treated hypothyroidism across the United Kingdom were therefore analyzed. Methods: Data covering the whole of the United Kingdom held by the National Health Service and the Office of National Statistics were examined. The main outcome measured was trends in the prevalence of treated hypothyroidism between 2005 and 2014. In addition, linear trend foreca...
2 Citations Source Cite
Published on Jan 1, 2019in The Lancet Diabetes & Endocrinology 24.54
Peter N. Taylor13
Estimated H-index: 13
(Cardiff University),
Salman Razvi21
Estimated H-index: 21
(Newcastle University)
+ 4 AuthorsKristien Boelaert30
Estimated H-index: 30
(University of Birmingham)
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Published on Jan 1, 2019in Annals of Clinical Biochemistry 1.89
Gautam Das4
Estimated H-index: 4
(Cwm Taf University Health Board),
Peter N. Taylor13
Estimated H-index: 13
(Cardiff University)
+ 4 AuthorsOnyebuchi E. Okosieme16
Estimated H-index: 16
(Cardiff University)
Background Microalbuminuria represents vascular and endothelial dysfunction. Thyroid hormones can influence urine albumin excretion as it exerts crucial effects on the kidney and on the vascular system. This study explores the relationship between serum thyrotropin and urine albumin excretion in euthyroid patients with diabetes. Methods A total of 433 patients with type 1 or 2 diabetes were included in this retrospective cross-sectional study. Data included anthropometric measurements and bioche...
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Published on Dec 1, 2018in Clinical Neurology and Neurosurgery 1.67
Matthew Roberts (University Hospital of Wales), Tessa Northmore (University Hospital of Wales)+ 2 AuthorsCaroline Hayhurst4
Estimated H-index: 4
(University Hospital of Wales)
Objectives The majority of patients with supratentorial diffuse grade II glioma present with seizures, which adversely affect quality of life. The exact mechanism of epileptogenesis is unknown and the influence of tumour characteristics, radiological and histological, are not well studied, particularly following the introduction of molecular genetics in the 2016 WHO reclassification of gliomas. We sought to define predictors of seizure development and outcome in low grade glioma. Patients and Me...
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Published on Nov 1, 2018
Ilaria Muller5
Estimated H-index: 5
,
Peter N. Taylor13
Estimated H-index: 13
,
John Lazarus20
Estimated H-index: 20
Thyroid hormones are essential for pregnancy maintenance and correct foetal development; even a mild thyroid disturbance can cause potential adverse consequences on obstetric outcomes and foetal well-being. Pregnancy also places substantial demands on the thyroid axis, with consequent increase of thyroid hormone requirements. Thus, it is critical to maintain appropriate levels of iodine and thyroid hormones during pregnancy. Thyroid disorders are relatively common in pregnancy, and a prompt diag...
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Published on Oct 25, 2018in Frontiers in Endocrinology 3.63
Peter N. Taylor13
Estimated H-index: 13
(Cardiff University),
Stamatios Zouras (Cwm Taf University Health Board)+ 3 AuthorsOnyebuchi E. Okosieme16
Estimated H-index: 16
(Cardiff University)
Universal thyroid screening in pregnancy is a key debate in thyroidology and obstetrics. It is well established that thyroid hormones are essential for maintaining pregnancy and optimal fetal development. Thyroid dysfunction is common in women of child-bearing age and also results in substantial adverse obstetric and child neurodevelopmental outcomes. Furthermore, thyroid dysfunction is readily diagnosed with reliable blood tests and easily corrected with inexpensive and available treatments. Sc...
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Published on Oct 1, 2018in The Journal of Clinical Endocrinology and Metabolism 5.61
Arash Derakhshan7
Estimated H-index: 7
(EUR: Erasmus University Rotterdam),
Tim I. M. Korevaar14
Estimated H-index: 14
(EUR: Erasmus University Rotterdam)
+ 6 AuthorsRobin P. Peeters43
Estimated H-index: 43
(EUR: Erasmus University Rotterdam)
Context Thyroperoxidase antibody (TPOAb) positivity is a major risk factor for gestational thyroid dysfunction. During the first 18 to 20 weeks of pregnancy, high concentrations of human chorionic gonadotropin (hCG) stimulate the thyroid to ensure adequate thyroid hormone availability for the developing fetus. However, TPOAb-positive women have an impaired thyroidal response to hCG stimulation. Objective To study the association of maternal TPOAb positivity during pregnancy with child IQ. Design...
1 Citations Source Cite
Published on Sep 11, 2018
Peter N. Taylor13
Estimated H-index: 13
,
Diana Albrecht1
Estimated H-index: 1
+ 4 AuthorsOnyebuchi E. Okosieme16
Estimated H-index: 16
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