Eva C.M. Nowack
University of Düsseldorf
19Publications
12H-index
945Citations
Publications 19
Newest
Published on Apr 1, 2019in Nature Ecology and Evolution
Benjamin J. Nettersheim1
Estimated H-index: 1
(Max Planck Society),
Jochen J. Brocks23
Estimated H-index: 23
(Australian National University)
+ 14 AuthorsP. De Deckker47
Estimated H-index: 47
(Australian National University)
The dawn of animals remains one of the most mysterious milestones in the evolution of life. The fossil lipids 24-isopropylcholestane and 26-methylstigmastane are considered diagnostic for demosponges—arguably the oldest group of living animals. The widespread occurrence and high relative abundance of these biomarkers in Ediacaran sediments from 635–541 million years (Myr) ago have been viewed as evidence for the rise of animals to ecological importance approximately 100 Myr before their rapid Ca...
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Published on Apr 29, 2018in Annual Review of Plant Biology 18.71
Eva C.M. Nowack12
Estimated H-index: 12
(University of Düsseldorf),
Andreas P. M. Weber57
Estimated H-index: 57
(University of Düsseldorf)
The conversion of free-living cyanobacteria to photosynthetic organelles of eukaryotic cells through endosymbiosis transformed the biosphere and eventually provided the basis for life on land. Despite the presumable advantage conferred by the acquisition of photoautotrophy through endosymbiosis, only two independent cases of primary endosymbiosis have been documented: one that gave rise to the Archaeplastida, and the other to photosynthetic species of the thecate, filose amoeba Paulinella. Here,...
6 Citations Source Cite
Published on Sep 1, 2017in Trends in Microbiology 11.78
Peter Mergaert5
Estimated H-index: 5
(University of Paris-Sud),
Yoshitomo Kikuchi30
Estimated H-index: 30
(National Institute of Advanced Industrial Science and Technology)
+ 1 AuthorsEva C.M. Nowack12
Estimated H-index: 12
(University of Düsseldorf)
Antimicrobial peptides (AMPs) are massively produced by eukaryotic hosts during symbiotic interactions with bacteria. Among other roles, these symbiotic AMPs have the capacity to permeabilize symbiont membranes and facilitate metabolite flow across the host–symbiont interface. We propose that an ancestral role of these peptides is to facilitate metabolic exchange between the symbiotic partners through membrane permeabilization. This function may be particularly critical for integration of endosy...
11 Citations Source Cite
Published on Apr 1, 2017in Plant Journal 5.78
Ru Zhang7
Estimated H-index: 7
(Carnegie Institution for Science),
Eva C.M. Nowack12
Estimated H-index: 12
(University of Düsseldorf)
+ 2 AuthorsArthur R. Grossman80
Estimated H-index: 80
(Carnegie Institution for Science)
Summary Plastid evolution has been attributed to a single primary endosymbiotic event that occurred about 1.6 billion years ago (BYA) in which a cyanobacterium was engulfed and retained by a eukaryotic cell, although early steps in plastid integration are poorly understood. The photosynthetic amoeba Paulinella chromatophora represents a unique model for the study of plastid evolution because it contains cyanobacterium-derived photosynthetic organelles termed ‘chromatophores’ that originated rela...
2 Citations Source Cite
Published on Sep 1, 2017in Current Biology 9.25
Anna Singer3
Estimated H-index: 3
(University of Düsseldorf),
Gereon Poschmann16
Estimated H-index: 16
(University of Düsseldorf)
+ 6 AuthorsEva C.M. Nowack12
Estimated H-index: 12
(University of Düsseldorf)
Summary The endosymbiotic acquisition of mitochondria and plastids more than 1 Ga ago profoundly impacted eukaryote evolution. At the heart of understanding organelle evolution is the re-arrangement of the endosymbiont proteome into a host-controlled organellar proteome. However, early stages in this process as well as the timing of events that underlie organelle integration remain poorly understood. The amoeba Paulinella chromatophora contains cyanobacterium-derived photosynthetic organelles, t...
16 Citations Source Cite
Eva C.M. Nowack12
Estimated H-index: 12
(University of Düsseldorf),
Dana C. Price19
Estimated H-index: 19
(Rutgers University)
+ 3 AuthorsArthur R. Grossman80
Estimated H-index: 80
(Carnegie Institution for Science)
Abstract Plastids, the photosynthetic organelles, originated >1 billion y ago via the endosymbiosis of a cyanobacterium. The resulting proliferation of primary producers fundamentally changed global ecology. Endosymbiotic gene transfer (EGT) from the intracellular cyanobacterium to the nucleus is widely recognized as a critical factor in the evolution of photosynthetic eukaryotes. The contribution of horizontal gene transfers (HGTs) from other bacteria to plastid establishment remains more contr...
34 Citations Source Cite
Published on Dec 1, 2016in BMC Evolutionary Biology 3.03
Jorge Morales1
Estimated H-index: 1
(University of Düsseldorf),
Sofia Kokkori1
Estimated H-index: 1
(University of Düsseldorf)
+ 5 AuthorsEva C.M. Nowack12
Estimated H-index: 12
(University of Düsseldorf)
Background Bacterial endosymbionts are found across the eukaryotic kingdom and profoundly impacted eukaryote evolution. In many endosymbiotic associations with vertically inherited symbionts, highly complementary metabolic functions encoded by host and endosymbiont genomes indicate integration of metabolic processes between the partner organisms. While endosymbionts were initially expected to exchange only metabolites with their hosts, recent evidence has demonstrated that also host-encoded prot...
9 Citations Source Cite
Wenqiang Yang15
Estimated H-index: 15
(Carnegie Institution for Science),
Tyler M. Wittkopp7
Estimated H-index: 7
(Stanford University)
+ 20 AuthorsMunevver Aksoy4
Estimated H-index: 4
(Carnegie Institution for Science)
Photosynthetic microorganisms typically have multiple isoforms of the electron transfer protein ferredoxin, although we know little about their exact functions. Surprisingly, a Chlamydomonas reinhardtii mutant null for the ferredoxin-5 gene (FDX5) completely ceased growth in the dark, with both photosynthetic and respiratory functions severely compromised; growth in the light was unaffected. Thylakoid membranes in dark-maintained fdx5 mutant cells became severely disorganized concomitant with a ...
22 Citations Source Cite
Published on Jan 31, 2015
Eva C.M. Nowack12
Estimated H-index: 12
,
Arthur R. Grossman80
Estimated H-index: 80
2 Citations Source Cite
Published on Jan 1, 2014in Acta Societatis Botanicorum Poloniae 0.88
Eva C.M. Nowack12
Estimated H-index: 12
(University of Düsseldorf)
Eukaryotes co-opted photosynthetic carbon fixation from prokaryotes by engulfing a cyanobacterium and stably integrating it as a photosynthetic organelle (plastid) in a process known as primary endosymbiosis. The sheer complexity of interactions between a plastid and the surrounding cell that started to evolve over 1 billion years ago, make it challenging to reconstruct intermediate steps in organelle evolution by studying extant plastids. Recently, the photosynthetic amoeba Paulinella chromatop...
29 Citations Source Cite
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