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Xinling Song
Shandong Agricultural University
21Publications
5H-index
104Citations
Publications 21
Newest
#1Wenshuai Wang (SDAU: Shandong Agricultural University)H-Index: 3
#2Honghong LiuH-Index: 2
Last.Le Jia (SDAU: Shandong Agricultural University)H-Index: 18
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Hyperlipidemia, a very common disease throughout the world, usually gives rise to severe liver damages. The current experiment was to investigate the antihyperlipidemic and hepatoprotective properties of alkali- and enzyme-extractable Dictyophora indusiata polysaccharides (Al-DPS and En-DPS) on the hyperlipidemic mice. The results of animal experiment in vivo showed that treatment with Al-DPS or En-DPS could improve the excessive level of lipid profiles in serum and liver, as well as strengthen ...
#2Zheng GaoH-Index: 7
Last.Chunyan HuangH-Index: 1
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As an irreversible and complex degenerative physiological process, the treatment for aging seems strategically necessary, and polysaccharides play important roles against aging owing to their abundant bioactivities. In this paper, the antioxidant and anti-aging activities of Flammulina velutipes polysaccharides (FPS) and its sulfated FPS (SFPS) on d-galactose-induced aging mice were investigated. The in vitro antioxidant activities demonstrated that SFPS had strong reducing power and superior sc...
#1Wenshuai Wang (SDAU: Shandong Agricultural University)H-Index: 3
#2Xinling Song (SDAU: Shandong Agricultural University)H-Index: 5
Last.Le Jia (SDAU: Shandong Agricultural University)H-Index: 18
view all 8 authors...
Abstract The present work aimed to investigate the antioxidant, hepatic and renal protective effects of water-extractable polysaccharides (WPS) by Dictyophora indusiata fruiting body on high-fat emulsion-induced obese mice. The structural analysis indicated that WPS was the α-configurational heteropolysaccharide with the major monosaccharides of mannose and glucose, and the polydispersity of 1.77. The in vivo results showed that WPS administration could improve obesity-associated hepatic and ren...
#1Huaping LiH-Index: 1
#2Huajie ZhaoH-Index: 9
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The present work mainly describes the preparation of acetylated mycelia polysaccharides (AMPS) from Pleurotus djamor and investigates the antioxidant and anti-aging effects in d-galactose-induced aging mice. The optimized procedure indicates the acetyl substitution degree of AMPS is 0.54 ± 0.04 under the conditions of a reaction time of 56 h, a reaction temperature of 37 °C, and 4 mL of added acetic anhydride. The in vitro analysis and in vivo animal experiments indicate that the AMPS could alle...
#1Wenshuai Wang (SDAU: Shandong Agricultural University)H-Index: 3
#2Xinling Song (SDAU: Shandong Agricultural University)H-Index: 5
Last.Le Jia (SDAU: Shandong Agricultural University)H-Index: 18
view all 7 authors...
Abstract In the present work, we investigated the anti-hyperlipidemic, antioxidant and organic protection effects of acidic-extractable Dictyophora indusiata polysaccharides (Ac-DPS) on hyperlipidemic mice induced by high-fat emulsion. The results demonstrated that Ac-DPS had impressive abilities to mitigate oxidative stress by increasing the activities of antioxidant enzyme and reducing the contents of lipid peroxide. Moreover, lipid levels in serum were returned to normal status. Besides, Ac-D...
#1Zheng Gao (SDAU: Shandong Agricultural University)H-Index: 7
#2Xinchao Liu (SDAU: Shandong Agricultural University)H-Index: 1
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Abstract The present work investigated the antioxidative, anti-inflammatory and pulmonary protective effects of enzymatic- and acid- hydrolysed mycelia polysaccharides (En-MPS and Ac-MPS) from Oudemansiella radicata on LPS-induced acute lung injury (ALI) mice. The results demonstrated that both En-MPS and Ac-MPS showed potential pulmonary protective effects by decreasing serum levels of hs-CRP and C3, increasing pulmonary enzyme values of SOD, GSH-Px, CAT and the level of T-AOC; reducing the act...
#1Xinling Song (SDAU: Shandong Agricultural University)H-Index: 5
#2Zhonghai LiuH-Index: 1
Last.Le Jia (SDAU: Shandong Agricultural University)H-Index: 18
view all 10 authors...
The present work investigated the hepatoprotective role of exopolysaccharides (EPS) isolated from the mushroom Pleurotus geesteranus with respect to alcohol-induced liver injury in mice. Based on a physico-chemical analysis, the EPS produced by Pleurotus geesteranus was identified as a heteropolysaccharide with α-glycosidic bond. The results revealed that prophylactic application of the EPS reduces detrimental alcoholic effects on the liver. This observation was followed by decreased levels of t...
#1Yuhan Dong (SDAU: Shandong Agricultural University)H-Index: 2
#2Yanran Qi (Jiangnan University)H-Index: 1
Last.Le Jia (SDAU: Shandong Agricultural University)H-Index: 18
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Abstract The aims of this work were to investigate the antioxidant, anti-hyperlipidemia and hepatic protection of Morehella esculenta polysaccharide (MPS) from fruiting body and its enzyme-assisted MPS (EnMPS). The in vitro scavenging rates of EnMPS at 600 mg/L on superoxide, hydroxyl and 1,1‑diphenyl‑2‑pyrazole hydrazide (DPPH) radicals were 76.92 ± 2.61%, 66.74 ± 2.56% and 75.78 ± 2.4%, higher than those of MPS, respectively. Animals experiments showed that the EnMPS exhibited superior abiliti...
#1Zhenzhen Ren (SDAU: Shandong Agricultural University)H-Index: 7
#2Wenbo Liu (SDAU: Shandong Agricultural University)H-Index: 1
Last.Le Jia (SDAU: Shandong Agricultural University)H-Index: 18
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Abstract The present work investigated the antioxidative, anti-inflammatory and organ protective effects of residue polysaccharide (RPS) and its enzymatic-RPS (ERPS) of Lentinula edodes against the LPS-induced sepsis in mice. The results demonstrated that ERPS showed superior effects on inhibiting serum activities of CKMB, LDH, AST, ALP and ALT, lowing the serum levels of BUN, CRE and UA, as well as improving the antioxidant status (SOD, CAT, GSH-P X and T-AOC) than RPS. Moreover, the levels of ...
#1Xiuxiu Wang (SDAU: Shandong Agricultural University)H-Index: 6
#2Yufei LanH-Index: 2
Last.Shouxian WangH-Index: 3
view all 11 authors...
The present work was designed to evaluate the antioxidation and hepatoprotective effects of Auricularia cornea var. Li. polysaccharides (APS) and enzymatic-extractable APS (EAPS) on the acute alcohol-induced alcoholic liver diseases (ALD). The in vitro antioxidant activities demonstrated that both APS and EAPS had strong reducing power and potential effects on scavenging reactive oxygen species. The in vivo mice experiments showed that the pretreatment with APS or EAPS showed potential hepatopro...
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