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Achuthan C. Raghavamenon
University of Calicut
23Publications
5H-index
81Citations
Publications 23
Newest
#1Nabarun Roy (Kerala Agricultural University)H-Index: 2
#2P. Nazeem (Kerala Agricultural University)H-Index: 4
Last.Achuthan C. Raghavamenon (University of Calicut)H-Index: 5
view all 8 authors...
Colorectal cancer is one among the most common cancers in the world and a major cause of cancer related deaths. Similar to other cancers, colorectal carcinogenesis is often associated with over expression of genes related to cell growth and proliferation, especially Epidermal Growth Factor Receptor (EGFR). There is an increasing attention towards the plant derived compounds in prevention of colorectal carcinogenesis by downregulating EGFR. Among plants, garlic (Allium sativum L.) is emerging wit...
#1Arunaksharan Narayanankutty (University of Calicut)H-Index: 6
#2Anu Anil (University of Calicut)H-Index: 1
Last.Achuthan C. Raghavamenon (University of Calicut)H-Index: 5
view all 5 authors...
Abstract Thermal oxidation products of edible oils including aldehydes, peroxides and polymerized triglycerides formed during the cooking process are increasingly debated as contributory to chronic degenerative diseases. Depending on the oil used for cooking, the source of fatty acids and its oxidation products may vary and would have a differential influence on the physiological process. Coconut oil (CO) is a medium chain triglyceride-rich edible oil used in South India and other Asia Pacific c...
#1Arunaksharan Narayanankutty (University of Calicut)H-Index: 6
#2Soorya Parathodi Illam (University of Calicut)H-Index: 4
Last.Achuthan C. Raghavamenon (University of Calicut)H-Index: 5
view all 3 authors...
Abstract Background Edible oils, preferably plant origin are rich sources of fatty acids and other lipophilic antioxidants to the body. Among these, oils derived from the coconut kernel ( Cocos nucifera ) are widely used in India and the Asia Pacific, which includes copra oil (CO), virgin coconut oil (VCO) and refined, bleached and deodorized (RBD) oil. Based on the mode of preparation, their composition and biological effects vary. Scope and approach This review compares the physicochemical and...
#1Arunaksharan Narayanankutty (University of Calicut)H-Index: 6
#2Midhun K. Gopinath (University of Calicut)
Last.Achuthan C. Raghavamenon (University of Calicut)H-Index: 5
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Abstract Docosahexaenoic acid (DHA) is long chain omega-3 fatty acid with known health benefits and clinical significance. However, 4-hydroxy hexenal (HHE), an enzymatic oxidation product of DHA has recently been reported to have health-damaging effects. This conflict raises major concern on the long-term clinical use of these fatty acids. Even though the enzymatic and non-enzymatic conversion of HHE to nontoxic acid molecules is possible by the aldehyde detoxification systems, it has not yet st...
#1Thomas ChubickaH-Index: 2
#2Devaki Girija (College of Horticulture)H-Index: 1
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Parasporins, a class of non-insecticidal crystal proteins of Bacillus thuringiensis (Bt) are being explored as promising anticancer agents due to their specific toxicity to cancer cells. The present study has identified 25 Bt isolates harbouring parasporin genes from Western Ghats region, the hotspot of biodiversity in India. Among these, the isolate, KAU 41 (Kerala Agricultural University isolate 41) contained non-hemolytic homogenous crystals showing specific cytotoxicity towards cancer cells....
#1Adangam Purath Shahid (Kerala Forest Research Institute)H-Index: 1
#2Nanu Sasidharan (Kerala Forest Research Institute)H-Index: 2
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Abstract Saraca asoca (Fabaceae) is a prime ingredient in Asokarishta , a well-known Ayurvedic preparation for gynecological ailments. Due to scarcity, adulteration or substitution of related raw drugs is a common practice in its preparation. The bark of Kingiodendron pinnatum (Roxb. ex DC.) Harms, morphologically similar to S. asoca (Asoka) is a widely used substitute. The present study aimed to evaluate the pharmacological effectiveness of K. pinnatum as an alternative for S. asoca in Asokaris...
#1Devi Lekshmi Sheela (Kerala Agricultural University)H-Index: 1
#2Puthiyaveetil Abdulla Nazeem (Kerala Agricultural University)H-Index: 3
Last.Achuthan C. Raghavamenon (Kerala Agricultural University)H-Index: 5
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Abstract Coconut oil (CO), the primary choice of cooking purposes in the south Asian countries, is rich in medium chain saturated fatty acids, especially lauric acid (50–52%). The oil has high medicinal use in Ayurvedic system and known to contain polyphenolic antioxidants. Studies have reported that CO improves insulin sensitivity and shows hypoglycemic effect. However, there is no information regarding its effect on chronic diabetic complications including retinopathy and nephropathy is availa...
#1Arunaksharan Narayanankutty (University of Calicut)H-Index: 6
#2Jj Manalil (University of Calicut)H-Index: 4
Last.Achuthan C. Raghavamenon (University of Calicut)H-Index: 5
view all 9 authors...
Hepatosteatosis is a complex disorder, in which insulin resistance and associated dyslipidemic and inflammatory conditions are fundamental. Dietary habit, especially regular consumption of fat and sugar-rich diet, is an important risk factor. Coconut and mustard oils (CO and MO) are medium-chain saturated and monounsaturated fats that are common dietary ingredients among the Indian populations. Present study analyzed the effect of prolonged consumption of the fresh and thermally oxidized forms o...
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