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Achuthan C. Raghavamenon
University of Calicut
23Publications
5H-index
81Citations
Publications 23
Newest
Published on Apr 3, 2019in Human & Experimental Toxicology 2.17
Dl Sheela (Kerala Agricultural University), Arunaksharan Narayanankutty6
Estimated H-index: 6
(University of Calicut)
+ 2 AuthorsSr Muthangaparambil (Kerala Agricultural University)
Nabarun Roy2
Estimated H-index: 2
(Kerala Agricultural University),
P. Nazeem4
Estimated H-index: 4
(Kerala Agricultural University)
+ 5 AuthorsAchuthan C. Raghavamenon5
Estimated H-index: 5
(University of Calicut)
Colorectal cancer is one among the most common cancers in the world and a major cause of cancer related deaths. Similar to other cancers, colorectal carcinogenesis is often associated with over expression of genes related to cell growth and proliferation, especially Epidermal Growth Factor Receptor (EGFR). There is an increasing attention towards the plant derived compounds in prevention of colorectal carcinogenesis by downregulating EGFR. Among plants, garlic (Allium sativum L.) is emerging wit...
Published on Nov 1, 2018in Prostaglandins Leukotrienes and Essential Fatty Acids 2.86
Arunaksharan Narayanankutty6
Estimated H-index: 6
(University of Calicut),
Anu Anil1
Estimated H-index: 1
(University of Calicut)
+ 2 AuthorsAchuthan C. Raghavamenon5
Estimated H-index: 5
(University of Calicut)
Abstract Thermal oxidation products of edible oils including aldehydes, peroxides and polymerized triglycerides formed during the cooking process are increasingly debated as contributory to chronic degenerative diseases. Depending on the oil used for cooking, the source of fatty acids and its oxidation products may vary and would have a differential influence on the physiological process. Coconut oil (CO) is a medium chain triglyceride-rich edible oil used in South India and other Asia Pacific c...
Arunaksharan Narayanankutty6
Estimated H-index: 6
(University of Calicut),
Midhun K. Gopinath (University of Calicut)+ 3 AuthorsAchuthan C. Raghavamenon5
Estimated H-index: 5
(University of Calicut)
Abstract Docosahexaenoic acid (DHA) is long chain omega-3 fatty acid with known health benefits and clinical significance. However, 4-hydroxy hexenal (HHE), an enzymatic oxidation product of DHA has recently been reported to have health-damaging effects. This conflict raises major concern on the long-term clinical use of these fatty acids. Even though the enzymatic and non-enzymatic conversion of HHE to nontoxic acid molecules is possible by the aldehyde detoxification systems, it has not yet st...
Published on Oct 1, 2018in Trends in Food Science and Technology 8.52
Arunaksharan Narayanankutty6
Estimated H-index: 6
(University of Calicut),
Soorya Parathodi Illam4
Estimated H-index: 4
(University of Calicut),
Achuthan C. Raghavamenon5
Estimated H-index: 5
(University of Calicut)
Abstract Background Edible oils, preferably plant origin are rich sources of fatty acids and other lipophilic antioxidants to the body. Among these, oils derived from the coconut kernel ( Cocos nucifera ) are widely used in India and the Asia Pacific, which includes copra oil (CO), virgin coconut oil (VCO) and refined, bleached and deodorized (RBD) oil. Based on the mode of preparation, their composition and biological effects vary. Scope and approach This review compares the physicochemical and...
Published on Jun 1, 2018in Journal of Biosciences 1.82
Thomas Chubicka2
Estimated H-index: 2
,
Devaki Girija1
Estimated H-index: 1
(College of Horticulture)
+ 5 AuthorsThekkekara Devassy Babu4
Estimated H-index: 4
Parasporins, a class of non-insecticidal crystal proteins of Bacillus thuringiensis (Bt) are being explored as promising anticancer agents due to their specific toxicity to cancer cells. The present study has identified 25 Bt isolates harbouring parasporin genes from Western Ghats region, the hotspot of biodiversity in India. Among these, the isolate, KAU 41 (Kerala Agricultural University isolate 41) contained non-hemolytic homogenous crystals showing specific cytotoxicity towards cancer cells....
Adangam Purath Shahid1
Estimated H-index: 1
(Kerala Forest Research Institute),
Nanu Sasidharan2
Estimated H-index: 2
(Kerala Forest Research Institute)
+ 4 AuthorsThekkekara Devassy Babu4
Estimated H-index: 4
Abstract Saraca asoca (Fabaceae) is a prime ingredient in Asokarishta , a well-known Ayurvedic preparation for gynecological ailments. Due to scarcity, adulteration or substitution of related raw drugs is a common practice in its preparation. The bark of Kingiodendron pinnatum (Roxb. ex DC.) Harms, morphologically similar to S. asoca (Asoka) is a widely used substitute. The present study aimed to evaluate the pharmacological effectiveness of K. pinnatum as an alternative for S. asoca in Asokaris...
Published on Dec 1, 2017in Prostaglandins Leukotrienes and Essential Fatty Acids 2.86
Devi Lekshmi Sheela1
Estimated H-index: 1
(Kerala Agricultural University),
Puthiyaveetil Abdulla Nazeem3
Estimated H-index: 3
(Kerala Agricultural University)
+ 6 AuthorsAchuthan C. Raghavamenon5
Estimated H-index: 5
(Kerala Agricultural University)
Abstract Coconut oil (CO), the primary choice of cooking purposes in the south Asian countries, is rich in medium chain saturated fatty acids, especially lauric acid (50–52%). The oil has high medicinal use in Ayurvedic system and known to contain polyphenolic antioxidants. Studies have reported that CO improves insulin sensitivity and shows hypoglycemic effect. However, there is no information regarding its effect on chronic diabetic complications including retinopathy and nephropathy is availa...
Published on Sep 1, 2017in Human & Experimental Toxicology 2.17
Arunaksharan Narayanankutty6
Estimated H-index: 6
(University of Calicut),
Jj Manalil4
Estimated H-index: 4
(University of Calicut)
+ 6 AuthorsAchuthan C. Raghavamenon5
Estimated H-index: 5
(University of Calicut)
Hepatosteatosis is a complex disorder, in which insulin resistance and associated dyslipidemic and inflammatory conditions are fundamental. Dietary habit, especially regular consumption of fat and sugar-rich diet, is an important risk factor. Coconut and mustard oils (CO and MO) are medium-chain saturated and monounsaturated fats that are common dietary ingredients among the Indian populations. Present study analyzed the effect of prolonged consumption of the fresh and thermally oxidized forms o...
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