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Marco Infante
University of Rome Tor Vergata
20Publications
2H-index
48Citations
Publications 22
Newest
#1Marco InfanteH-Index: 2
#2Camillo RicordiH-Index: 83
Last.Rodolfo AlejandroH-Index: 48
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Recurrence of autoimmunity and allograft rejection represent major challenges that impact the success of islet transplantation. Despite the remarkable improvements achieved in immunosuppression strategies after the publication of the Edmonton protocol, long-term data of intra-hepatic islet transplantation show a gradual decline in beta-cell function. Therefore, there is a growing interest in the investigation of novel, safe and effective anti-inflammatory and immunomodulatory strategies able to ...
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RANKL/RANK/OPG system consists of three essential signaling molecules: i) the receptor activator of nuclear factor (NF)-kB-ligand (RANKL), ii) the receptor activator of NF-kB (RANK), and iii) the soluble decoy receptor osteoprotegerin (OPG). Although this system is critical for the regulation of osteoclast differentiation/activation and calcium release from the skeleton, different studies have elucidated its specific role in mammary gland physiology and hormone-driven epithelial proliferation du...
1 CitationsSource
#1Massimiliano Caprio (OU: Open University)H-Index: 25
#2Marco Infante (University of Rome Tor Vergata)H-Index: 2
Last.Andrea Lenzi (Sapienza University of Rome)H-Index: 57
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Background Weight loss is a milestone in the prevention of chronic diseases associated with high morbility and mortality in industrialized countries. Very-low calorie ketogenic diets (VLCKDs) are increasingly used in clinical practice for weight loss and management of obesity-related comorbidities. Despite evidence on the clinical benefits of VLCKDs is rapidly emerging, some concern still exists about their potential risks and their use in the long-term, due to paucity of clinical studies. Notab...
2 CitationsSource
#1Andrea ArmaniH-Index: 12
#2Vincenzo MarzollaH-Index: 9
Last.Massimiliano CaprioH-Index: 25
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#2Marco InfanteH-Index: 1
Last.David Della-MorteH-Index: 26
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Atherosclerosis is an inflammatory chronic disease affecting arterial vessels and leading to vascular diseases, such as stroke and myocardial infarction. The relationship between atherosclerosis and risk of neurodegeneration has been established, in particular with vascular cognitive impairment and dementia (VCID). Systemic atherosclerosis increases the risk of VCID by inducing cerebral infarction, or through systemic or local inflammatory factors that underlie both atherosclerosis and cognition...
3 CitationsSource
#1Stefania GoriniH-Index: 8
Last.Massimiliano Caprio (OU: Open University)H-Index: 25
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The mineralocorticoid receptor (MR) was originally identified as a regulator of blood pressure, able to modulate renal sodium handling in response to its principal ligand aldosterone. MR is also expressed in many tissues other than kidney, including the heart, vasculature and adipose tissue. More recent studies have shown that extra-renal MR plays a relevant role in the control of cardiovascular and metabolic functions and has recently been implicated in the pathophysiology of aging. MR activati...
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#1Eleonora Moriconi (Policlinico Umberto I)
#2Marco InfanteH-Index: 2
Last.Massimiliano CaprioH-Index: 25
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La very-low-calorie-ketogenic-diet (VLCKD) rappresenta un valido strumento nel trattamento dell’obesita e delle sue comorbidita. Il vantaggio di una VLCKD rispetto a un trattamento ipocalorico tradizionale e rappresentato dal rapido calo ponderale, dal mantenimento della massa muscolare e dalla riduzione dell’appetito. La VLCKD e spesso utilizzata all’interno di un percorso di educazione alimentare che abitua gradualmente il paziente a consumare porzioni di cibo piu piccole, ponendo maggiore att...
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#1Massimiliano CaprioH-Index: 25
#2E. MoriconiH-Index: 1
Last.AntonioAversaH-Index: 40
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#1Marco InfanteH-Index: 2
#2Andrea ArmaniH-Index: 12
Last.Massimiliano Caprio (OU: Open University)H-Index: 25
view all 5 authors...
Abstract Mineralocorticoid receptor (MR) has been recently identified in adipose tissue, where its excessive activation contributes to several metabolic derangements often observed in obesity and metabolic syndrome. Recent findings support the existence of a bidirectional cross-talk between adipose tissue and adrenal glands, contributing to obesity-related hyperaldosteronism and subsequent adipocyte MR excessive activation. In this regard, MR pharmacological blockade has led to prevention of wei...
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