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Ching-Chu Chen
China Medical University (PRC)
EndocrinologyType 2 diabetesPopulationDiabetes mellitusMedicine
102Publications
20H-index
1,485Citations
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Publications 112
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#1Hsin-Hung Chen (PRC: China Medical University (PRC))H-Index: 6
Last. Chia-Hung Kao (PRC: China Medical University (PRC))H-Index: 42
view all 8 authors...
Background: To investigate the association between gout treatment and heart failure (HF). Methods: Patients with gout between 2000 and 2010 constituted the gout cohort. The main outcome was a new diagnosis of HF. Multivariable Cox proportional hazard regression models were used to measure the effect of gout on the risk of developing HF. The Kaplan-Meier method was used to estimate the cumulative HF incidence curve for the gout and nongout cohorts. Results: The cohort study included 50,166 patien...
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#1Hsin‐Hung Chen (CSMU: Chung Shan Medical University)
#1Hsin-Hung Chen (CSMU: Chung Shan Medical University)H-Index: 6
Last. Chia-Hung KaoH-Index: 42
view all 7 authors...
Objectives: To evaluate the risk of periodontal disease (PD) in gout patients.Methods: This retrospective cohort study was conducted using data from the Longitudinal Health Insurance Database 2000. The gout cohort included 31,759 patients newly diagnosed with gout from 2000 to 2012, and the comparison (nongout) cohort included 63,517 patients. Univariate and multivariable adjusted hazard ratios (aHRs), with corresponding 95% confidence intervals (CIs), were estimated using the Cox proportional h...
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#1Jia-Yin Guo (PRC: China Medical University (PRC))
#2Chia-Ling Chang (PRC: China Medical University (PRC))
Last. Ching-Chu Chen (PRC: China Medical University (PRC))H-Index: 20
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BACKGROUND: Thionamides have been extensively used to treat patients with hyperthyroidism worldwide. Recent pharmacovigilance studies have revealed a safety signal between carbimazole or methimazole and pancreatitis. The associated risk remains unclear. METHODS: We identified patients with newly diagnosed acute pancreatitis from 2000 to 2013 as the case group from the Taiwan Longitudinal Health Insurance Database 2000, which contains data from 1996 to 2013. Each patient with acute pancreatitis w...
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#1Hsin-Hung Chen (CSMU: Chung Shan Medical University)
#1Hsin-Hung Chen (CSMU: Chung Shan Medical University)H-Index: 6
Last. Chia-Hung Kao (PRC: China Medical University (PRC))H-Index: 42
view all 7 authors...
Background: To investigate the association between Graves' disease (GD) and polycystic ovary syndrome (PCOS) and its comorbidities.Methods: Logistic regression was performed to determine the association between the two conditions. Cumulative incidence curves were obtained using the Kaplan-Meier method and log-rank test. Hazard ratios were determined using the Cox proportional hazards regression model.Results: We included 5,399 patients with GD as the study group and 10,798 patients without GD as...
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#1Chun-Wei Ho (PRC: China Medical University (PRC))
#2Hsin-Hung Chen (PRC: China Medical University (PRC))H-Index: 6
Last. Chia-Hung Kao (PRC: China Medical University (PRC))H-Index: 42
view all 7 authors...
Objective: To investigate the prevalence of polycystic ovary syndrome (PCOS) and its comorbidities in patients with autoimmune thyroid disease (AITD). Population: In this cohort study, patients newly diagnosed as having Hashimoto thyroiditis (HT) or Grave disease (GD) were recruited into the AITD group. Method: The logistic regression model was used to investigate the association between exposure, endpoint, later diseases and treatment. Main Outcome Measures: We assessed the cumulative incidence...
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#1Jia-Yin Guo (PRC: China Medical University (PRC))H-Index: 1
#2Hsin Hung Chen (CSMU: Chung Shan Medical University)H-Index: 1
Last. Ching-Chu Chen (PRC: China Medical University (PRC))H-Index: 20
view all 6 authors...
Abstract Background Bullous pemphigoid (BP) is an autoimmune blistering skin disorder with unknown etiology. Evidence revealed that dipeptidyl peptidase IV inhibitors (DPP4i) may increase the associated risk. This study aimed to evaluate the relationship of BP with the administration of DPP4i and other risk factors in patients with type 2 diabetes mellitus (T2DM). Methods Using the Taiwan National Health Insurance Database (NHIRD) from 2009 to 2013, we identified patients with T2DM and the use o...
2 CitationsSource
#1Juei‐Yu Tseng (PRC: China Medical University (PRC))
#2Hsin-Hung Chen (CSMU: Chung Shan Medical University)H-Index: 6
Last. Ching-Chu Chen (PRC: China Medical University (PRC))
view all 5 authors...
AIM: To evaluate the effect of mean HbA1c on the correlation between HbA1c variability and all-cause mortality, and the risks associated with different levels of HbA1c and glycaemic control status in patients with type 2 diabetes. MATERIALS AND METHODS: Patients with type 2 diabetes and at least three HbA1c measurements within 12-24 months were included. HbA1c variability score, coefficient of variation (CV) and standard deviation (SD) were used to evaluate variability. A variability score of 50...
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#1Li Na Liao (PRC: China Medical University (PRC))H-Index: 6
#1Li-Na Liao (PRC: China Medical University (PRC))H-Index: 1
Last. Cheng Chieh Lin (PRC: China Medical University (PRC))H-Index: 42
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We evaluated whether genetic information could offer improvement on risk prediction of diabetic nephropathy (DN) while adding susceptibility variants into a risk prediction model with conventional risk factors in Han Chinese type 2 diabetes patients. A total of 995 (including 246 DN cases) and 519 (including 179 DN cases) type 2 diabetes patients were included in derivation and validation sets, respectively. A genetic risk score (GRS) was constructed with DN susceptibility variants based on find...
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#1Yu-Chuen Huang (PRC: China Medical University (PRC))H-Index: 7
Last. Fuu Jen Tsai (PRC: China Medical University (PRC))H-Index: 53
view all 8 authors...
BACKGROUND/AIM: C-Reactive protein (CRP) is a common marker of inflammation. Elevated CRP levels have been associated with increased risk of development of type 2 diabetes mellitus (T2DM). This study aimed to evaluate the association of CRP gene polymorphisms with early-onset T2DM and the effect of genetic variants on CRP level. MATERIALS AND METHODS: In total, 948 individuals with early-onset (n=271) or late-onset (n=677) T2DM were enrolled in the study. Five single-nucleotide polymorphisms (SN...
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