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Xiuli Wang
Tongji University
63Publications
11H-index
416Citations
Publications 64
Newest
#1Jianhua Huang (Fudan University)
#2Mingquan Guo (Fudan University)
Last.Hong-Wei Wang (Fudan University)H-Index: 11
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Abstract In recent years, the emergence of drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), has brought great difficulties to clinical treatment. Antibacterial photodynamic therapy (aPDT) is a new non-antibiotic treatment strategy for a variety of drug-resistant bacteria. However, there are few studies on the antimicrobial mechanism of aPDT mediated by 5-aminolevulinic acid (ALA-PDT) for MRSA. In this study, we observed the bactericidal effect of ALA-PDT on MR...
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Abstract Background 5-aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT) is a reliable treatment for actinic keratosis (AK), and the concentration of ALA for this treatment is 20% in most studies, but it was found that 10% ALA could achieve similar outcome during clinical practice while reducing the costs. However, there are limited reports comparing the efficacy and the safety of 5-aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT) with different ALA doses. Objectives This...
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#1Peiru Wang (Tongji University)H-Index: 6
#2Weitao Yang (Tongji University)H-Index: 12
Last.Xiuli Wang (Tongji University)H-Index: 11
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Elevated hydrogen peroxide (H2O2) in biological tissues is generally recognized to be relevant to the carcinogenesis process that regulates the proliferative activity of cancer cells and the transformation of malignant features. Inspired by this observation, it can be hypothesized that imaging H2O2 in the tumor microenvironment (TME) could help diagnose tumor types and malignancy, and even guide precise therapy. Thus, in this study, a noninvasive photomedicine strategy is demonstrated that lever...
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#1Lei Shi (LMU: Ludwig Maximilian University of Munich)H-Index: 1
#2Alexander Buchner (LMU: Ludwig Maximilian University of Munich)H-Index: 29
Last.Ronald Sroka (LMU: Ludwig Maximilian University of Munich)H-Index: 18
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1 CitationsSource
#1Shan-shan Li (Fudan University)H-Index: 1
#2Peiru Wang (Tongji University)H-Index: 6
Last.Hong-Wei Wang (Fudan University)H-Index: 11
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Abstract Cancer-associated fibroblasts (CAFs) are important components of the tumor microenvironment, affecting the biological behavior of tumor cells and playing critical roles in tumor growth, invasion, and metastasis. Topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) is an established approach for the treatment of non-melanoma skin cancers. It is reported that ALA-PDT treating cutaneous squamous cell carcinoma(cSCC) also induce antitumor immune effect and has an impact on ...
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#1Chunxiao Li (Tongji University)
#2Lehang Guo (Tongji University)H-Index: 1
Last.Xiuli Wang (Tongji University)H-Index: 11
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Abstract Extramammary Paget’s disease (EMPD) is a rare intraepithelial neoplasm arising in apocrine rich area of the skin. Surgery is the standard treatment but relapse is common. The postoperative skin defects, penile reconstruction, functional effects and old age are also challenges for curing disease. Herein, a case of postoperative recurrent EMPD, which was treated by combination therapy of non-invasive repeatable ALA-PDT and deep penetrated holmium laser is reported. Ultrasonography monitor...
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#1Lei Shi (Tongji University)H-Index: 7
#2Pei Liu (Tongji University)H-Index: 2
Last.Xiuli Wang (Tongji University)H-Index: 11
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Aim: To clarify the effectiveness and safety of x-ray-activated photodynamic therapy (X-PDT) for cutaneous squamous cell carcinoma (SCC) and melanoma. Materials & methods: Copper-cysteamine nanopar...
2 CitationsSource
#1Ping Tu (PKU: Peking University)H-Index: 3
#2Haiyan Zhang (Tongji University)
Last.Xiuli Wang (Tongji University)H-Index: 11
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#1Lude Zhu (Tongji University)H-Index: 2
#2Guolong Zhang (Tongji University)H-Index: 5
Last.Xiuli Wang (Tongji University)H-Index: 11
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Abstract Background Active recruitment of inflammatory cells into tumors may be vital for antitumor immunity in cutaneous squamous cell carcinoma (cSCC) after photodynamic therapy. Chemokines play important roles in inflammatory cell recruitment. Moreover, C-X-C motif chemokine ligand 13 (CXCL13) is thought to be a pivotal chemokine involved in inflammatory response and antitumor effect. Here, we examined the roles of CXCL13 in the response of cSCC to ALA-PDT. Methods Microarray analysis was use...
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#1Jie Ji (Tongji University)H-Index: 5
#2Peiru Wang (Tongji University)H-Index: 6
Last.Xiuli Wang (Tongji University)H-Index: 11
view all 10 authors...
Abstract Background Antitumor immunity induced by photodynamic therapy (PDT) is believed to depend on the degree of local and systemic inflammation. The recruitment of leukocytes, in particular by the chemokine CCL8, to the sites of tissue damage has been strongly associated with the initiation of inflammatory reactions. Objective To evaluate whether and how CCL8 enhances the immune response against tumors in 5-aminolevulinic acid (ALA)-mediated PDT. Methods In this study, we investigated the ef...
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