Mads Vendelbo Lind
University of Copenhagen
EndocrinologyMetabolic syndromeDiabetes mellitusMedicineBiology
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Publications 45
#1Martin Frederik Laursen (DTU: Technical University of Denmark)H-Index: 7
#2Melanie Wange Larsson (UCPH: University of Copenhagen)H-Index: 3
Last. Tine Rask Licht (DTU: Technical University of Denmark)H-Index: 40
view all 8 authors...
Epidemiological evidence indicates that breastfeeding provides protection against development of overweight/obesity. Nonetheless, a small subgroup of infants undergo excessive weight gain during exclusive breastfeeding, a phenomenon that remains unexplained. Breastmilk contains both gut-seeding microbes and substrates for microbial growth in the gut of infants, and a large body of evidence suggests a role for gut microbes in host metabolism. Based on the recently established SKOT III cohort, we ...
#1Hanne Hauger (UCPH: University of Copenhagen)H-Index: 5
#2Rikke Pilmann Laursen (UCPH: University of Copenhagen)H-Index: 7
Last. Camilla T. Damsgaard (UCPH: University of Copenhagen)H-Index: 23
view all 6 authors...
In observational studies, higher S-25-hydroxyvitamin D [S-25(OH)D] has been associated with a more favorable cardiometabolic profile in childhood, but results may be confounded. We examined effects of vitamin D supplementation on cardiometabolic outcomes in children and adolescents. We systematically searched relevant databases for randomized controlled trials (RCTs) examining effects of vitamin D supplementation compared to placebo or a lower dose of vitamin D on blood glucose, insulin, homeost...
3 CitationsSource
#1Ceyda Tugba Pekmez (Hacettepe University)H-Index: 2
#2Melanie Wange Larsson (UCPH: University of Copenhagen)H-Index: 3
Last. Lars O. Dragsted (UCPH: University of Copenhagen)H-Index: 54
view all 10 authors...
SCOPE: The aim is to identify breastmilk components associated with fecal concentration of SCFAs and to investigate whether they differ between infants with high weight gain (HW) and normal weight gain (NW). METHODS AND RESULTS: Breastmilk and fecal samples are collected from mother-infant dyads with HW (n = 11) and NW (n = 15) at 5 and 9 months of age. Breastmilk is profiled on ultra-performance LC-quadrupole TOF-MS platform. Fecal SCFAs are quantified using an isotope-labeled chemical derivati...
#1Martin Frederik Laursen (DTU: Technical University of Denmark)H-Index: 7
#2Mikiyasu Sakanaka (DTU: Technical University of Denmark)H-Index: 1
Last. Christian Mølgaard (UCPH: University of Copenhagen)H-Index: 49
view all 20 authors...
Breastfeeding profoundly shapes the infant gut microbiota, which is critical for early life immune development. However, few breastmilk-dependent microbial metabolites mediating host-microbiota interactions are currently known. We here demonstrate that breastmilk-promoted Bifidobacterium species convert aromatic amino acids (tryptophan, phenylalanine and tyrosine) into their respective aromatic lactic acids (indolelactate, phenyllactate and 4-hydroxyphenyllactate) via a previously unrecognised a...
4 CitationsSource
#2Grith HøjfeldtH-Index: 2
Last. Lars HolmH-Index: 29
view all 9 authors...
#1Sandra Monsonis-Centelles (UvA: University of Amsterdam)
#2Huub C. J. Hoefsloot (UvA: University of Amsterdam)H-Index: 35
Last. Mads Vendelbo Lind (UCPH: University of Copenhagen)H-Index: 10
view all 5 authors...
Background: Characterization of lipoprotein particle profiles (LPPs) (including main classes and subclasses) by means of ultracentrifugation (UC) is highly requested given its clinical potential. However, rapid methods are required to replace the very labor-intensive UC method and one solution is to calibrate rapid nuclear magnetic resonance (NMR)-based prediction models, but the reliability of the UC-response method required for the NMR calibration has been largely overlooked. Methods: This stu...
#1Anna Viitasalo (UCPH: University of Copenhagen)H-Index: 12
#2Theresia M. Schnurr (UCPH: University of Copenhagen)H-Index: 5
Last. Tuomas O. Kilpelaeinen (UCPH: University of Copenhagen)H-Index: 35
view all 23 authors...
BACKGROUND: Mendelian randomization studies in adults suggest that abdominal adiposity is causally associated with increased risk of type 2 diabetes and coronary artery disease in adults, but its causal effect on cardiometabolic risk in children remains unclear. OBJECTIVE: We aimed to study the causal relation of abdominal adiposity with cardiometabolic risk factors in children by applying Mendelian randomization. METHODS: We constructed a genetic risk score (GRS) using variants previously assoc...
1 CitationsSource
#1Josué L. Castro-Mejía (UCPH: University of Copenhagen)H-Index: 8
#2Bekzod Khakimov (UCPH: University of Copenhagen)H-Index: 15
Last. Dennis S. Nielsen (UCPH: University of Copenhagen)H-Index: 37
view all 22 authors...
When humans age, changes in body composition arise along with lifestyle-associated disorders influencing fitness and physical decline. Here we provide a comprehensive view of dietary intake, physical activity, gut microbiota (GM) and host metabolome in relation to physical fitness of 207 community dwelling subjects aged +65 years. Stratification on anthropometric/body-composition/physical-performance measurements (ABPm) variables identified two phenotypes (high/low-fitness) clearly linked to die...
2 CitationsSource
#1Violetta Aru (UCPH: University of Copenhagen)H-Index: 4
#2Chloie Lam (UvA: University of Amsterdam)H-Index: 1
Last. Søren Balling Engelsen (UCPH: University of Copenhagen)H-Index: 51
view all 11 authors...
#1Simon Rønnow Schacht (UCPH: University of Copenhagen)H-Index: 2
#2Mads Vendelbo Lind (UCPH: University of Copenhagen)H-Index: 10
Last. Inge Tetens (UCPH: University of Copenhagen)H-Index: 41
view all 14 authors...
Introduction Risk of both osteoporosis and sarcopenia are major concerns of many older individuals. Reduced bone mineral density (BMD) and muscle function is associated with increased risk of multiple health related issues. Diet may play a role in sustaining BMD and muscle function throughout old age, but much is still to be learned with regards to which specific food groups and dietary patterns that are most important for such outcomes. The aim of the current study was to identify food groups i...