Hongwei Zhang
Fourth Military Medical University
CancerSurgeryPathologyCancer researchMedicine
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Publications 111
#1Gaozan Zheng (Fourth Military Medical University)H-Index: 6
#2Jinqiang Liu (Fourth Military Medical University)H-Index: 2
Last. Fan Feng (Fourth Military Medical University)H-Index: 9
view all 10 authors...
BACKGROUND: It remains controversial whether prophylactic No.10 lymph node clearance is necessary for gastric cancer. Thus, the present study aims to investigate the impact of prophylactic No.10 lymph node clearance on the perioperative complications and prognosis of upper and middle third gastric cancer. METHODS: A network meta-analysis to identify both direct and indirect evidence with respect to the comparison of gastrectomy alone (G-A), gastrectomy combination with splenectomy (G + S) and ga...
#1Shuao XiaoH-Index: 2
#2Fan FengH-Index: 9
Last. Hongwei ZhangH-Index: 12
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Objective The preoperative value of albumin level and albumin/globulin ratio (AGR) has been discovered to be a possibility for predicting gastric cancer. However, their predictive accuracy remains unknown. This study’s objective is to evaluate the predictive value of albumin, globulin and AGR in gastric cancer.
#2Jinqiang LiuH-Index: 2
Last. Fan FengH-Index: 9
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#1Fei Wang (Fourth Military Medical University)H-Index: 3
#2Shushang Liu (Fourth Military Medical University)H-Index: 7
Last. Hongwei Zhang (Fourth Military Medical University)H-Index: 12
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Abstract Background Substance P (SP) plays an important role in several types of cancer promotion and progression by binding to its preferential neurokinin 1 receptor (NK1R). However, the clinical significance and downstream mechanism of NK1R in esophageal squamous cell carcinoma (ESCC) have not been elucidated. The aim of this study was to investigate the role of SP/NK1R in the proliferation of ESCC and to screen related downstream molecules. Methods In the current investigation, the expression...
#1Hongwei ZhangH-Index: 12
#2Jianjun YangH-Index: 11
Last. Guocai LiH-Index: 1
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AbstractTo evaluate the value of intraperitoneal hyperthermic perfusion (IPHP) in the treatment of gastric cancer.Gastric cancer (GC) is a malignancy with poor prognosis, recent years have demonstrated advances in the use of IPHP for the treatment of advanced gastric cancer (AGC), but the outcome is
#1Wanli Yang (Fourth Military Medical University)H-Index: 4
#2Xinhui Zhao (Fourth Military Medical University)H-Index: 1
Last. Dai-MingFan (Fourth Military Medical University)H-Index: 55
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Background Esophageal squamous cell carcinoma (ESCC) is one of leading malignant cancers of gastrointestinal tract worldwide. Until now, the involved mechanisms during the development of ESCC are largely unknown. This study aims to explore the driven-genes and biological pathways in ESCC.
#1Lili DuanH-Index: 1
#2Wanli YangH-Index: 4
Last. Dai-MingFanH-Index: 55
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ABSTRACTIntroduction: Colorectal cancer (CRC) is one of the most common malignant tumors worldwide and contributes significantly to cancer-related deaths. Since CRC is largely asymptomatic until alarm features develop to advanced stages, the incidence and mortality rate of CRC is relatively high and increases year by year.Areas covered: This review mainly summarizes the recent advances of genetic, epigenetic, and proteomic molecular markers that may be used to predict the prognosis of CRC. Moreo...
#1Jinqiang Liu (Fourth Military Medical University)H-Index: 4
#2Fei Wang (Fourth Military Medical University)H-Index: 3
Last. Fan Feng (Fourth Military Medical University)H-Index: 9
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Abstract Background Caspase 3 is not only involved in apoptosis, but also participates in the nonapoptotic functions. Previously, we found that caspase 3 gene knockout mice displayed decreased number of dendritic cells (DCs). However, whether caspase 3 participate in the function of DCs is unclear. Thus, the present study aims to investigate the role of caspase 3 in the maturation and antitumor function of DCs. Methods Caspase 3 gene was overexpressed in DC2.4 cell line through Lentivirus system...
#1Wanli YangH-Index: 4
#2Yu HanH-Index: 16
Last. Dai-MingFanH-Index: 55
view all 14 authors...
ABSTRACTIntroduction: Esophageal cancer (EC) is one of the deadliest neoplasms in Asian countries. The high mortality rate and low survival rate of this disease are the major challenges for patient...
1 CitationsSource
#1Wanli YangH-Index: 4
#2Jiaojiao MaH-Index: 6
Last. Daiming FanH-Index: 2
view all 9 authors...
Hypoxia inducible factor-1α (HIF-1α) is a central molecule involved in mediating cellular processes. Alterations of HIF-1α and hypoxically regulated microRNAs (miRNAs) are correlated with patients’ outcome in various cancers, indicating their crucial roles on cancer development. Recently, an increasing number of studies have revealed the intricate regulations between miRNAs and HIF-1α in modulating a wide variety of processes, including proliferation, metastasis, apoptosis, and drug resistance, ...
4 CitationsSource