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Hongwei Zhang
Fourth Military Medical University
69Publications
10H-index
437Citations
Publications 69
Newest
Published on Dec 1, 2019in Cancer Cell International3.44
Wanli Yang3
Estimated H-index: 3
(Fourth Military Medical University),
Xinhui Zhao (Fourth Military Medical University)+ 10 AuthorsHongwei Zhang10
Estimated H-index: 10
(Fourth Military Medical University)
Esophageal squamous cell carcinoma (ESCC) is one of leading malignant cancers of gastrointestinal tract worldwide. Until now, the involved mechanisms during the development of ESCC are largely unknown. This study aims to explore the driven-genes and biological pathways in ESCC. mRNA expression datasets of GSE29001, GSE20347, GSE100942, and GSE38129, containing 63 pairs of ESCC and non-tumor tissues data, were integrated and deeply analyzed. The bioinformatics approaches include identification of...
Published on 2019in Medicine1.87
Hongwei Zhang10
Estimated H-index: 10
,
Jianjun Yang10
Estimated H-index: 10
+ 3 AuthorsGuocai Li1
Estimated H-index: 1
Published on May 1, 2019in Biochemical and Biophysical Research Communications2.71
Fei Wang1
Estimated H-index: 1
,
Shushang Liu6
Estimated H-index: 6
+ 10 AuthorsMan Guo7
Estimated H-index: 7
Abstract Background Substance P (SP) plays an important role in several types of cancer promotion and progression by binding to its preferential neurokinin 1 receptor (NK1R). However, the clinical significance and downstream mechanism of NK1R in esophageal squamous cell carcinoma (ESCC) have not been elucidated. The aim of this study was to investigate the role of SP/NK1R in the proliferation of ESCC and to screen related downstream molecules. Methods In the current investigation, the expression...
Published on Apr 3, 2019in Expert Review of Molecular Diagnostics3.10
Lili Duan , Wanli Yang3
Estimated H-index: 3
+ 7 AuthorsDai-MingFan53
Estimated H-index: 53
ABSTRACTIntroduction: Colorectal cancer (CRC) is one of the most common malignant tumors worldwide and contributes significantly to cancer-related deaths. Since CRC is largely asymptomatic until alarm features develop to advanced stages, the incidence and mortality rate of CRC is relatively high and increases year by year.Areas covered: This review mainly summarizes the recent advances of genetic, epigenetic, and proteomic molecular markers that may be used to predict the prognosis of CRC. Moreo...
Published on Apr 1, 2019in Biochemical and Biophysical Research Communications2.71
Jinqiang Liu4
Estimated H-index: 4
(Fourth Military Medical University),
Fei Wang1
Estimated H-index: 1
(Fourth Military Medical University)
+ 2 AuthorsFan Feng8
Estimated H-index: 8
(Fourth Military Medical University)
Abstract Background Caspase 3 is not only involved in apoptosis, but also participates in the nonapoptotic functions. Previously, we found that caspase 3 gene knockout mice displayed decreased number of dendritic cells (DCs). However, whether caspase 3 participate in the function of DCs is unclear. Thus, the present study aims to investigate the role of caspase 3 in the maturation and antitumor function of DCs. Methods Caspase 3 gene was overexpressed in DC2.4 cell line through Lentivirus system...
Published on Feb 1, 2019in Expert Review of Molecular Diagnostics3.10
Wanli Yang3
Estimated H-index: 3
,
Yu Han15
Estimated H-index: 15
+ 11 AuthorsJinqiang Liu4
Estimated H-index: 4
ABSTRACTIntroduction: Esophageal cancer (EC) is one of the deadliest neoplasms in Asian countries. The high mortality rate and low survival rate of this disease are the major challenges for patients. Therefore, exploring novel biomarkers for prognosis analysis is still an important task for cancer research.Areas covered: The aim of our review is to summarize the recent advances in prognostic markers for EC. We also discuss the pros and cons of different types of biomarkers for improving the judg...
Published on Feb 1, 2019in Cellular and Molecular Life Sciences7.01
Wanli Yang3
Estimated H-index: 3
,
Jiaojiao Ma5
Estimated H-index: 5
+ 6 AuthorsDai-MingFan53
Estimated H-index: 53
Hypoxia inducible factor-1α (HIF-1α) is a central molecule involved in mediating cellular processes. Alterations of HIF-1α and hypoxically regulated microRNAs (miRNAs) are correlated with patients’ outcome in various cancers, indicating their crucial roles on cancer development. Recently, an increasing number of studies have revealed the intricate regulations between miRNAs and HIF-1α in modulating a wide variety of processes, including proliferation, metastasis, apoptosis, and drug resistance, ...
Published on Jan 1, 2019in Digestive Surgery1.88
Fan Feng8
Estimated H-index: 8
,
Fei Wang1
Estimated H-index: 1
+ 7 AuthorsHongwei Zhang10
Estimated H-index: 10
Published on Dec 1, 2018in Cancer management and research2.24
Wanli Yang3
Estimated H-index: 3
,
Jiaojiao Ma5
Estimated H-index: 5
+ 10 AuthorsHongwei Zhang10
Estimated H-index: 10
Published on Dec 1, 2018in BMC Cancer2.93
Fan Feng8
Estimated H-index: 8
(Fourth Military Medical University),
Gaozan Zheng5
Estimated H-index: 5
(Fourth Military Medical University)
+ 7 AuthorsHongwei Zhang10
Estimated H-index: 10
(Fourth Military Medical University)
Background The association between body mass index (BMI) and clinical outcomes of gastric cancer were still under debate. The aim of the present study was to investigate the impact of BMI on intraoperative conditions, postoperative complications and prognosis of gastric cancer.
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