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Jordi Rodon
University of Texas MD Anderson Cancer Center
156Publications
23H-index
3,425Citations
Publications 162
Newest
Purpose To estimate the maximum tolerated dose (MTD) and/or identify the recommended Phase II dose (RP2D) for combined INC280 and buparlisib in patients with recurrent glioblastoma with homozygous phosphatase and tensin homolog (PTEN) deletion, mutation or protein loss.
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We investigated two independent cohorts of patients with advanced solid tumours treated in phase I trials with (i) programmed cell death 1 (PD-1)/PDL-1 antibodies in monotherapy or combination; and (ii) targeted agents (TAs) in unapproved indications. A RECIST 1.1 (RECIST) -based definition of hyperprogression was developed. The primary endpoint was the assessment of the rate of HPD in patients treated with ICIs or TAs using both criteria (RECIST and TGR) and the impact on overall survival (OS) ...
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#1Ecaterina E Ileana Dumbrava (University of Texas MD Anderson Cancer Center)H-Index: 3
#2Kavitha Balaji (Lexicon Pharmaceuticals)H-Index: 4
Last.Funda Meric-Bernstam (University of Texas MD Anderson Cancer Center)H-Index: 76
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PURPOSEHuman epidermal growth factor receptor 2 (HER2) is an effective therapeutic target in breast and gastric and gastroesophageal junction cancers. However, less is known about the prevalence of...
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#1Aung Naing (University of Texas MD Anderson Cancer Center)H-Index: 41
#2Funda Meric-Bernstam (University of Texas MD Anderson Cancer Center)H-Index: 76
Last.Gauri R. Varadhachary (University of Texas MD Anderson Cancer Center)H-Index: 6
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#1Anna SpreaficoH-Index: 13
#2Filip Janku (University of Texas MD Anderson Cancer Center)H-Index: 41
Last.Nehal J. LakhaniH-Index: 8
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#1Juanita Lopez (ICR: Institute of Cancer Research)H-Index: 13
#2R Shinde (ICR: Institute of Cancer Research)
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#1Alison M. Schram (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 12
#2A. Drilon (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 8
Last.J Tabernero (Hebron University)H-Index: 11
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#1Ginevra CaratuH-Index: 6
Last.Ana VivancosH-Index: 16
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#1Jing LiH-Index: 2
#2Frederick F. LangH-Index: 62
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