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Zhenzhen Ren
Shandong Agricultural University
22Publications
7H-index
133Citations
Publications 22
Newest
#1Zheng Gao (SDAU: Shandong Agricultural University)H-Index: 7
#2Xinchao Liu (SDAU: Shandong Agricultural University)H-Index: 1
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Abstract The present work investigated the antioxidative, anti-inflammatory and pulmonary protective effects of enzymatic- and acid- hydrolysed mycelia polysaccharides (En-MPS and Ac-MPS) from Oudemansiella radicata on LPS-induced acute lung injury (ALI) mice. The results demonstrated that both En-MPS and Ac-MPS showed potential pulmonary protective effects by decreasing serum levels of hs-CRP and C3, increasing pulmonary enzyme values of SOD, GSH-Px, CAT and the level of T-AOC; reducing the act...
#1Huijuan Jing (SDAU: Shandong Agricultural University)H-Index: 6
#2Qing Zhang (SDAU: Shandong Agricultural University)
Last.Le Jia (SDAU: Shandong Agricultural University)H-Index: 18
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This study aimed to investigate the antioxidant, antiaging, and organ protective effects of the water-extractable mycelium polysaccharides (MPS) and enzymic-extractable mycelium polysaccharides (En-MPS) by Agrocybe aegerita (Brig.) Sing in D-galactose-induced (D-gal-induced) aging mice. In in vitro assays, the En-MPS demonstrated stronger antioxidant activities in dose-dependent manners. The mice experiments revealed that both En-MPS and MPS had potential effects on antioxidation, antiaging, and...
#1Xinling Song (SDAU: Shandong Agricultural University)H-Index: 5
#2Zhonghai LiuH-Index: 1
Last.Le Jia (SDAU: Shandong Agricultural University)H-Index: 18
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The present work investigated the hepatoprotective role of exopolysaccharides (EPS) isolated from the mushroom Pleurotus geesteranus with respect to alcohol-induced liver injury in mice. Based on a physico-chemical analysis, the EPS produced by Pleurotus geesteranus was identified as a heteropolysaccharide with α-glycosidic bond. The results revealed that prophylactic application of the EPS reduces detrimental alcoholic effects on the liver. This observation was followed by decreased levels of t...
#1Zhenzhen Ren (SDAU: Shandong Agricultural University)H-Index: 7
#2Wenbo Liu (SDAU: Shandong Agricultural University)H-Index: 1
Last.Le Jia (SDAU: Shandong Agricultural University)H-Index: 18
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Abstract The present work investigated the antioxidative, anti-inflammatory and organ protective effects of residue polysaccharide (RPS) and its enzymatic-RPS (ERPS) of Lentinula edodes against the LPS-induced sepsis in mice. The results demonstrated that ERPS showed superior effects on inhibiting serum activities of CKMB, LDH, AST, ALP and ALT, lowing the serum levels of BUN, CRE and UA, as well as improving the antioxidant status (SOD, CAT, GSH-P X and T-AOC) than RPS. Moreover, the levels of ...
#1Xinling Song (SDAU: Shandong Agricultural University)H-Index: 5
#2Zhonghai LiuH-Index: 1
Last.Le Jia (SDAU: Shandong Agricultural University)H-Index: 18
view all 10 authors...
Abstract The present work investigated the antioxidant and hepatoprotective effects of acidic- and enzymatic-hydrolysis mycelium polysaccharide (AcMPS and EnMPS) from Pleurotus geesteranus on alcoholic liver disease (ALD) mice. The animal studies demonstrated that the polysaccharides had potential effects reflected by remitting alcoholic hepatitis, reducing lipid accumulation, preventing oxidative stress, improving inflammatory symptoms, and alleviating the liver functions by histopathologic obs...
#1Zheng Gao (SDAU: Shandong Agricultural University)H-Index: 7
#2Chen Zhang (SDAU: Shandong Agricultural University)H-Index: 10
Last.Le Jia (SDAU: Shandong Agricultural University)H-Index: 18
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Abstract The selenium polysaccharides (SPS) by Oudemansiella radicata were isolated, and two hydrolysates (enzymatic-SPS (ESPS) and acidic-SPS (ASPS)) were obtained by enzymolysis and acidolysis. The endo-toxemic-induced lung and kidney damages were successfully established by the lipopolysaccharides (LPS) injection (5 mg/kg/d). The in vivo mice experiments indicated that the ESPS showed superior antioxidant and protective effects against the LPS-toxicities by increasing the antioxidant activiti...
#1Xinling Song (SDAU: Shandong Agricultural University)H-Index: 5
#2Qiang Shen (SDAU: Shandong Agricultural University)H-Index: 1
Last.Jianjun Zhang (SDAU: Shandong Agricultural University)H-Index: 16
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Abstract In the present study, we investigated the antioxidant and hepatoprotective effects of intracellular mycelium polysaccharides from Pleurotus geesteranus (IMPP) to address acute alcoholic liver diseases (ALD). Animal studies have demonstrated that the hepatic parameters of CYP2E1, MPO, TC, ALT, AST and ALP, HDLC, LDL-C and VLDL-C were improved; the inflammatory factor levels, including TNF-α, IL-1β and IL-6, were decreased; the hepatic ADH and ALDH activities were inhibited; the activitie...
#1Shangshang Li (SDAU: Shandong Agricultural University)H-Index: 8
#2Min Liu (SDAU: Shandong Agricultural University)H-Index: 9
Last.Weiru LiuH-Index: 3
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Abstract In present study, the soluble polysaccharides by enzyme-assisted extraction from Agaricus bisporus (EnAPS) and its purified fractions of EnAPS-1, -2 and -3 were successfully obtained, and the antioxidant activities and anti-aging effects were investigated. The in vitro antioxidant assay demonstrated that EnAPS-2 had superior scavenging activities on DPPH and hydroxyl radicals, chelating activities of Fe 2+ and reducing power. The in vivo animal experiments showed that both EnAPS and its...
#1Zheng Gao (SDAU: Shandong Agricultural University)H-Index: 7
#2Chen Zhang (SDAU: Shandong Agricultural University)H-Index: 10
Last.Weiru LiuH-Index: 3
view all 12 authors...
Abstract The present work investigated the characteristics, antioxidative, anti-inflammative and renoprotective effects of mycelia selenized polysaccharides (MSPS) from Oudemansiella radicata on lipopolysaccharide (LPS)-induced kidney damaged mice. The results demonstrated that both MSPS and mycelia polysaccharides (MPS) showed potential renoprotective effects reflecting by decreasing the serum levels of CRE, BUN and UA, increasing the nephritic enzyme activities of SOD, GSH-Px, CAT and T-AOC, r...
#1Shangshang Li (SDAU: Shandong Agricultural University)H-Index: 8
#2Hui Liu (SDAU: Shandong Agricultural University)H-Index: 3
Last.Xinling Song (SDAU: Shandong Agricultural University)H-Index: 5
view all 11 authors...
Abstract This study was designed to investigate the antioxidant and anti-aging effects of D-galatose-induced (D-gal-induced) aging mice as well as monosaccharide compositions of acidic-extractable polysaccharides (AcAPS) and its major purified fractions (AcAPS-1, AcAPS-2 and AcAPS-3) from the fruiting body of Agaricus bisporus . In the in vitro assays, AcAPS-2 showed superior scavenging activities on hydroxyl (82.98 ± 4.67%) and DPPH (64.47 ± 4.05%) radicals at the concentration of 1.0 mg/mL tha...
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