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Ramona Dölling
University of Münster
3Publications
1H-index
5Citations
Publications 3
Newest
#1Martha N. Mendelski (WWU: University of Münster)H-Index: 1
#2Ramona Dölling (WWU: University of Münster)H-Index: 1
Last.Bodo Philipp (WWU: University of Münster)H-Index: 20
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Bile acids are steroid compounds from the digestive tracts of vertebrates that enter agricultural environments in unusual high amounts with manure. Bacteria degrading bile acids can readily be isolated from soils and waters including agricultural areas. Under laboratory conditions, these bacteria transiently release steroid compounds as degradation intermediates into the environment. These compounds include androstadienediones (ADDs), which are C19-steroids with potential hormonal effects. Exper...
#1Ramona Dölling (WWU: University of Münster)H-Index: 1
#2Martha N. Mendelski (WWU: University of Münster)H-Index: 1
Last.Rüdiger J. Paul (WWU: University of Münster)H-Index: 26
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Abstract Stress may have negative or positive effects in dependence of its intensity (hormesis). We studied this phenomenon in Caenorhabditis elegans by applying weak or severe abiotic (cadmium, CdCl 2 ) and/or biotic stress (different bacterial diets) during cultivation/breeding of the worms and determining their developmental speed or survival and performing transcriptome profiling and RT-qPCR analyses to explore the genetic basis of the detected phenotypic differences. To specify weak or seve...
#1Alex Keshet (WWU: University of Münster)H-Index: 3
#2Ansgar Mertenskötter (WWU: University of Münster)H-Index: 4
Last.Rüdiger J. Paul (WWU: University of Münster)H-Index: 26
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The mechanisms of cadmium (Cd) resistance are complex and not sufficiently understood. The present study, therefore, aimed at assessing the roles of important components of stress-signaling pathways and of ABC transporters under severe Cd stress in Caenorhabditis elegans. Survival assays on mutant and control animals revealed a significant promotion of Cd resistance by the PMK-1 p38 MAP kinase, the transcription factor DAF-16/FoxO, and the ABC transporter MRP-1. Transcriptome profiling by RNA-Se...
#1Sarah A. Winter (WWU: University of Münster)H-Index: 1
#2Ramona Dölling (WWU: University of Münster)H-Index: 1
Last.Rüdiger J. Paul (WWU: University of Münster)H-Index: 26
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The present study employed mass spectrometry (ICP-MS) to measure the internal cadmium concentrations (Cdint) in Caenorhabditis elegans to determine Cd uptake from a Cd-containing environment as well as Cd release under Cd-free conditions. To analyze the functional role of several ATP binding cassette (ABC) transporters (e.g., HMT-1 and MRP-1) and phytochelatin synthase (PCS), we compared wild-type (WT) and different mutant strains of C. elegans. As a pre-test on selected mutant strains, several ...
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