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Luisa A. DiPietro
University of Illinois at Chicago
127Publications
41H-index
10.1kCitations
Publications 127
Newest
Published on Dec 1, 2018in Journal of Translational Medicine 4.20
Sridevi Nagaraja2
Estimated H-index: 2
,
Lin Chen15
Estimated H-index: 15
(University of Illinois at Chicago)
+ 2 AuthorsAlexander Y. Mitrophanov7
Estimated H-index: 7
Background Pathological scarring in wounds is a prevalent clinical outcome with limited prognostic options. The objective of this study was to investigate whether cellular signaling proteins could be used as prognostic biomarkers of pathological scarring in traumatic skin wounds.
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Published on Jan 1, 2018
Alyne Simões (University of São Paulo), Zujian Chen (University of Illinois at Chicago)+ 4 AuthorsXiaofeng Zhou28
Estimated H-index: 28
(University of Illinois at Chicago)
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Published on Dec 1, 2018in Scientific Reports 4.12
Elizabeth R. Michalczyk1
Estimated H-index: 1
(University of Illinois at Chicago),
Lin Chen15
Estimated H-index: 15
(University of Illinois at Chicago)
+ 4 AuthorsLuisa A. DiPietro41
Estimated H-index: 41
(University of Illinois at Chicago)
Although the inflammatory and proliferative phases of wound healing have been well described, much less is known about how healing resolves. During the resolution phase, pruning of the capillary bed and maturation of capillaries occurs and influences the final strength and fidelity of the wound. PEDF, an endogenous anti-angiogenic factor, is produced in wounds and may contribute to the removal of capillaries during wound resolution. This study utilized PEDF−/− mice to examine how PEDF influences...
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Published on Sep 25, 2018in Langmuir 3.79
Jiayu Leong2
Estimated H-index: 2
(Agency for Science, Technology and Research),
Yongbeom Seo16
Estimated H-index: 16
(University of Illinois at Urbana–Champaign)
+ 7 AuthorsHyunjoon Kong40
Estimated H-index: 40
Hydrogen peroxide (H2O2) is an attractive chemical because of its bleaching properties in paper and pulp industry and as a disinfectant in the food, water, and medical industries. However, it is important to monitor the residual H2O2 level after its usage and prevent any unintended health problems or chemical reactions. Most H2O2 sensors often utilize fluorophores or electrical circuitry that requires an additional irradiation or a digital display. To this end, this study presents a 3,3′,5,5′-te...
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Published on Dec 18, 2018in Langmuir 3.79
Min Kyung Lee7
Estimated H-index: 7
(University of Illinois at Urbana–Champaign),
Nicholas E. Clay4
Estimated H-index: 4
(University of Illinois at Urbana–Champaign)
+ 7 AuthorsHyunjoon Kong40
Estimated H-index: 40
Superparamagnetic iron oxide nanoparticles (SPIONs) are often encapsulated into drug-carrying nano/micro-sized particles for simultaneous magnetic resonance (MR) imaging and treatment of diseased tissues. Unfortunately, encapsulated SPIONs may have a limited ability to modulate the T2-weighted relaxation of water protons, but this insight has not been examined systematically. This study demonstrates that SPIONs immobilized on 200 nm-diameter poly(lactic-co-glycolic acid) (PLGA) nanoparticles usi...
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Published on Jul 3, 2017in International Journal of Molecular Sciences 3.69
Uzoagu A. Okonkwo2
Estimated H-index: 2
(University of Illinois at Chicago),
Luisa A. DiPietro41
Estimated H-index: 41
Diabetes Mellitus Type II (DM2) is a growing international health concern with no end in sight. Complications of DM2 involve a myriad of comorbidities including the serious complications of poor wound healing, chronic ulceration, and resultant limb amputation. In skin wound healing, which has definite, orderly phases, diabetes leads to improper function at all stages. While the etiology of chronic, non-healing diabetic wounds is multi-faceted, the progression to a non-healing phenotype is closel...
17 Citations Source Cite
Published on Jan 15, 2017in Journal of Immunology 4.54
Sridevi Nagaraja2
Estimated H-index: 2
,
Lin Chen15
Estimated H-index: 15
(University of Illinois at Chicago)
+ 5 AuthorsAlexander Y. Mitrophanov7
Estimated H-index: 7
Wound fibrosis (i.e., excessive scar formation) is a medical problem of increasing prevalence, with poorly understood mechanistic triggers and limited therapeutic options. In this study, we employed an integrated approach that combines computational predictions with new experimental studies in mice to identify plausible mechanistic triggers of pathological scarring in skin wounds. We developed a computational model that predicts the time courses for six essential cell types, 18 essential molecul...
1 Citations Source Cite
Published on May 1, 2017in Wound Repair and Regeneration 2.95
Lin Chen15
Estimated H-index: 15
(University of Illinois at Chicago),
Sridevi Nagaraja2
Estimated H-index: 2
+ 5 AuthorsLuisa A. DiPietro41
Estimated H-index: 41
(University of Illinois at Chicago)
Mac-1 (CD11b/CD18) is a macrophage receptor that plays several critical roles in macrophage recruitment and activation. Because macrophages are essential for proper wound healing, the impact of Mac-1 deficiency on wound healing is of significant interest. Prior studies have shown that Mac-1−/− mice exhibit deficits in healing, including delayed wound closure in scalp and ear wounds. This study examined whether Mac-1 deficiency influences wound healing in small excisional and incisional skin woun...
2 Citations Source Cite
Published on Nov 1, 2016in Journal of Leukocyte Biology 4.22
Luisa A. DiPietro41
Estimated H-index: 41
(University of Illinois at Chicago)
31 Citations Source Cite
Published on Jan 11, 2016in PLOS ONE 2.77
Yan Zhao4
Estimated H-index: 4
(University of Illinois at Chicago),
Lei Bao10
Estimated H-index: 10
(University of Illinois at Chicago)
+ 2 AuthorsLin Chen15
Estimated H-index: 15
(University of Illinois at Chicago)
Wound healing in a pre-existing Th2-dominated skin milieu was assessed by using an epidermal specific interleukin-4 (IL-4) transgenic (Tg) mouse model, which develops a pruritic inflammatory skin condition resembling human atopic dermatitis. Our results demonstrated that IL-4 Tg mice had delayed wound closure and re-epithelialization even though these mice exhibited higher degrees of epithelial cell proliferation. Wounds in IL-4 Tg mice also showed a marked enhancement in expression of inflammat...
12 Citations Source Cite
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