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Yu-Lin Huang
National Cheng Kung University
CellTranscriptional regulationMALAT1Cancer researchBiology
2Publications
2H-index
28Citations
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Publications 2
Newest
#1I-Ying Kuo (NCKU: National Cheng Kung University)H-Index: 6
#2Yu-Lin Huang (NCKU: National Cheng Kung University)H-Index: 2
Last. Yi-Ching Wang (NCKU: National Cheng Kung University)H-Index: 28
view all 7 authors...
Prognosis of esophageal squamous cell carcinoma (ESCC) patients is poor and the concurrent chemoradiation therapy (CCRT) provided to ESCC patients often failed due to resistance. Therefore, development of biomarkers for predicting CCRT response is immensely important. In this study, we evaluated the predicting value of SRY (sex determining region Y)-box 17 (SOX17) protein during CCRT and its dysregulation of transcriptional targets in CCRT resistance in ESCC. Pyrosequencing methylation, RT-qPCR ...
2 CitationsSource
#1I-Ying Kuo (NCKU: National Cheng Kung University)H-Index: 6
#2Ching-Chi Wu (NCKU: National Cheng Kung University)H-Index: 1
Last. Yi-Ching Wang (NCKU: National Cheng Kung University)H-Index: 28
view all 11 authors...
The transcriptional network of the SRY (sex determining region Y)-box 17 (SOX17) and the prognostic impact of SOX17 protein expression in human cancers remain largely unclear. In this study, we evaluated the prognostic effect of low SOX17 protein expression and its dysregulation of transcriptional network in esophageal squamous cell carcinoma (ESCC). Low SOX17 protein expression was found in 47.4% (73 of 154) of ESCC patients with predicted poor prognosis. Re-expression of SOX17 in ESCC cells ca...
26 CitationsSource
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