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Kayeong Lim
Seoul National University
6Publications
5H-index
344Citations
Publications 6
Newest
#1Gue-Ho Hwang (Hanyang University)H-Index: 3
#2Jeongbin Park (Charité)H-Index: 11
Last.Sangsu Bae (Hanyang University)H-Index: 15
view all 10 authors...
As a result of its simplicity and high efficiency, the CRISPR-Cas system has been widely used as a genome editing tool. Recently, CRISPR base editors, which consist of deactivated Cas9 (dCas9) or Cas9 nickase (nCas9) linked with a cytidine or a guanine deaminase, have been developed. Base editing tools will be very useful for gene correction because they can produce highly specific DNA substitutions without the introduction of any donor DNA, but dedicated web-based tools to facilitate the use of...
6 CitationsSource
#1Gue-Ho Hwang (Hanyang University)H-Index: 3
#2Jeongbin Park (DKFZ: German Cancer Research Center)H-Index: 11
Last.Sangsu Bae (Hanyang University)H-Index: 15
view all 9 authors...
Background: As a result of its simplicity and high efficiency, the CRISPR-Cas system has been widely used as a genome editing tool. Recently, CRISPR base editors, which consist of deactivated Cas9 (dCas9) or Cas9 nickase (nCas9) linked with a cytidine or a guanine deaminase, have been developed. Base editing tools will be very useful for gene correction because they can produce highly specific DNA substitutions without the introduction of any donor DNA, but dedicated web-based tools to facilitat...
3 CitationsSource
#1Seuk-Min RyuH-Index: 4
#2Taeyoung KooH-Index: 15
Last.Jin-Soo KimH-Index: 53
view all 11 authors...
Adenine base editing is used to treat a mouse model of Duchenne muscular dystrophy and to create defined mutations in mouse embryos.
48 CitationsSource
#1Kyoungmi KimH-Index: 4
#2Seuk-Min RyuH-Index: 4
Last.Jin-Soo KimH-Index: 53
view all 9 authors...
Mice with targeted point mutations are generated efficiently using Cas9–cytidine deaminase fusions.
145 CitationsSource
#1Daesik KimH-Index: 14
#2Kayeong LimH-Index: 5
Last.Jin-Soo KimH-Index: 53
view all 7 authors...
Base editors composed of Cas9 fused to a deaminase show high specificity in genome-wide analyses.
82 CitationsSource
#1Jeongbin Park (Hanyang University)H-Index: 11
#2Kayeong Lim (SNU: Seoul National University)H-Index: 5
Last.Sangsu Bae (Hanyang University)H-Index: 15
view all 4 authors...
60 CitationsSource
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