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T. R. van Oudheusden
10Publications
6H-index
102Citations
Publications 10
Newest
Combining chemotherapy and targeted therapies has resulted in an enhanced survival in metastatic colorectal cancer (mCRC) patients. However, the result of this palliative treatment in patients with metachronous peritoneal carcinomatosis (PC) remains unknown. The current population-based study aims to investigate the use and effect of palliative systemic treatment in patients with metachronous PC of colorectal origin. Data on metachronous PC were collected between 2010 and 2011 for all patients w...
7 CitationsSource
#1H.J. BraamH-Index: 10
Last.Bert van RamshorstH-Index: 38
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#1R. A. DevileeH-Index: 1
#2Geert A. SimkensH-Index: 8
Last.I.H.J.T. de HinghH-Index: 36
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Background Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS + HIPEC) can result in long-term survival for selected patients with colorectal peritoneal metastases (PM). Most patients are additionally treated with systemic chemotherapy, but timing (adjuvant vs. preoperative) varies between treatment centers. This study aimed to compare short- and long-term outcomes for patients with synchronous colorectal PM undergoing CRS + HIPEC who received preoperative or adjuvant chemo...
8 CitationsSource
#2Simon W. NienhuijsH-Index: 29
Last.I.H.J.T. de HinghH-Index: 36
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Abstract Introduction The optimal treatment for peritoneal carcinomatosis (PC) of colorectal origin is a combination of cytoreductive surgery and intraperitoneal chemotherapy (CRS + IPC). Although 5-year survival rates of up to 40% have been reported, recurrent disease remains common and is estimated to be a strong negative prognostic factor for survival. This systematic review elaborates on the incidence of recurrent disease and the possibilities to prevent and treat recurrence. Methods Two sea...
14 CitationsSource
#2H.J. BraamH-Index: 10
Last.I.H.J.T. de HinghH-Index: 36
view all 7 authors...
Background Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is currently the only curative option for patients with peritoneal carcinomatosis of colorectal origin. Despite meticulous preoperative assessment, CRS and HIPEC appear to be impossible in a subset of patients at the time of surgery. This study investigated which clinical factors may identify these patients before surgery and reported on factors influencing survival.
24 CitationsSource
#2H.J. BraamH-Index: 10
Last.I.H.J.T. de HinghH-Index: 36
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Background: Signet ring cell cancer (SRCC) patients have a poor oncologic outcome. The aim of this study was to determine whether the potential drawbacks of hyperthermic intraperitoneal chemotherapy (HIPEC) outweigh the benefits in patients with peritoneally metastasized SRCC. Methods: Patients with peritoneal carcinomatosis (PC) of colorectal origin referred to two tertiary centers between April 2005 and December 2013 were identified and retrospectively analyzed. Data were compared between SRCC...
33 CitationsSource
#2H.J. BraamH-Index: 10
Last.I.H.J.T. de HinghH-Index: 36
view all 8 authors...
1 CitationsSource
#1H.J. BraamH-Index: 10
Last.Bert van RamshorstH-Index: 38
view all 7 authors...
Source
#2H.J. BraamH-Index: 10
Last.I.H.J.T. de HinghH-Index: 36
view all 7 authors...
1 CitationsSource
#1Irene ThomassenH-Index: 7
Last.I.H.J.T. de HinghH-Index: 36
view all 7 authors...
Abstract Background During resection of a colorectal tumor a careful inspection of the abdomen should be performed to detect metastases. The aim of the current study was to compare the proportions of patients diagnosed with peritoneal carcinomatosis (PC) during laparoscopic resection (LR) and open resection (OR). Methods All patients who underwent resection for colorectal cancer in the Eindhoven Cancer Registry area between 2008 and 2012 were included. Proportions of patients with PC were compar...
14 CitationsSource
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