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Ajeet Singh
Indian Institute of Technology Guwahati
Key distributionSession keyXcastGroup keyPre-shared key
4Publications
3H-index
16Citations
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Publications 4
Newest
#1Shaik Abduldileep (CSIR: Council of Scientific and Industrial Research)
#2Raja Narayanasamy (CSIR: Council of Scientific and Industrial Research)
Last. Ram Rajasekharan (AcSIR: Academy of Scientific and Innovative Research)H-Index: 21
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Abstract Human sucrase enzyme is a key therapeutic target for type 2 diabetes. While sugarcane sucrase inhibitor (sucinh) modulates invertase activity thereby accumulates sucrose. Molecular level understanding of sucinh towards mammalian α-glucosidases is scarce. The interaction of sucinh with human sucrase was identified and the association of these proteins was confirmed using co-purification, co-immunoprecipitation and pull-down assay. In addition, microscale thermophoresis assay showed that ...
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#1Ajeet Singh (IITG: Indian Institute of Technology Guwahati)H-Index: 3
#2Abshar Hasan (IITG: Indian Institute of Technology Guwahati)H-Index: 12
Last. Lalit M. Pandey (IITG: Indian Institute of Technology Guwahati)H-Index: 16
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BACKGROUND & OBJECTIVE: Over the last two decades, Alzheimer disease (AD) associated research has accomplished an overwhelming momentum, as it is one of the major current healthcare issues in the developed world. AD is characterized by the presence of Aβ mediated extracellular amyloid fibrils and tau-mediated intracellular neurofibrillar tangles and reports have highlighted their subsequent effects on neuronal synaptic activity, antioxidant response and recently explored mitochondrial dysfunctio...
5 CitationsSource
#1Ajeet Singh (IITG: Indian Institute of Technology Guwahati)H-Index: 3
#2Poulami Datta (IITG: Indian Institute of Technology Guwahati)H-Index: 3
Last. Lalit M. Pandey (IITG: Indian Institute of Technology Guwahati)H-Index: 16
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Abstract Various metal ions are recently implicated in protein aggregates and are associated with numerous neurodegenerative diseases. In the present work, we have scrutinized the effect of stoichiometric variation of Cu(II) on BSA fibrillation at physiological pH 7.4 through Thioflavin-T dye binding study, residual protein concentration, Fourier Transform Infrared spectroscopy (FTIR), Dynamic Light Scattering (DLS), Atomic Force Microscopy (AFM) and Isothermal Titration Calorimetry (ITC). Fibri...
5 CitationsSource
#1Ajeet Singh (IITG: Indian Institute of Technology Guwahati)H-Index: 3
#2Swapnil M. Potey (IITG: Indian Institute of Technology Guwahati)H-Index: 1
Last. Sukumar Nandi (IITG: Indian Institute of Technology Guwahati)H-Index: 23
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The benefits of multicasting are becoming evermore apparent and its usage is getting more importance than ever. Providing security services for multicast, such as traffic integrity, authentication and confidentiality is challenging since it requires secure distribution of group key to each of the group members. Traditionally, the key distribution function has been assigned to a central network entity, or Key Distribution Center (KDC), but this method does not scale for wide-area multicasting. Ou...
3 CitationsSource
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