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Timothy R. Shope
University of Pittsburgh
SurgeryIntensive care medicinePediatricsDiabetes mellitusMedicine
22Publications
8H-index
489Citations
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Publications 30
Newest
#1Nader Shaikh (University of Pittsburgh)H-Index: 24
#2Timothy R. Shope (University of Pittsburgh)H-Index: 8
Last. Howard E. Rockette (University of Pittsburgh)H-Index: 48
view all 20 authors...
BACKGROUND To evaluate the efficacy of adjuvant systemic corticosteroids in reducing kidney scarring. A previous study suggested that use of adjuvant systemic corticosteroids reduces kidney scarring in children radiologically confirmed to have extensive pyelonephritis. Efficacy of corticosteroids for children with febrile urinary tract infection (UTI) has not been studied. METHODS Children aged 2 months to 6 years with their first febrile UTI were randomized to corticosteroids or placebo for 3 d...
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#1Nader Shaikh (University of Pittsburgh)H-Index: 24
#2Judith M. Martin (University of Pittsburgh)H-Index: 19
Last. Timothy R. Shope (University of Pittsburgh)H-Index: 8
view all 16 authors...
Background The specificity of the leukocyte esterase test (87%) is suboptimal. The objective of this study was to identify more specific screening tests that could reduce the number of children who unnecessarily receive antimicrobials to treat a presumed urinary tract infection (UTI).
1 CitationsSource
#1Timothy R. Shope (University of Pittsburgh)H-Index: 8
#2Benjamin H. Walker (MSU: Mississippi State University)H-Index: 2
Last. Judith M. Martin (University of Pittsburgh)H-Index: 19
view all 5 authors...
BACKGROUND: Influenza vaccine is the most effective means to prevent influenza for the high-risk population of child care attendees. This national survey assessed child care center directors' reports of seasonal influenza vaccine requirements for children and adult caregivers. METHODS: This was a 2016 telephone-based survey of child care center directors randomly selected from a national database of licensed United States child care centers and queried about influenza vaccine requirements. Conce...
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#1Timothy R. Shope (University of Pittsburgh)H-Index: 8
#2Cathy P. Chen (University of Pittsburgh)
Last. Nader Shaikh (University of Pittsburgh)H-Index: 24
view all 4 authors...
Objectives: To determine the effectiveness and feasibility of cerumen removal using three irrigation methods and a metal curette in young children. Study Design: Pilot study conducted as a randomized clinical trial of well and ill children age 6 months to 6 years with ≥25% cerumen occlusion in at least one ear. Children were stratified by age and randomized to one of four methods of cerumen removal: syringe with attached angiocath tubing, Elephant Ear Washer Bottle System®, OtoClear Spray Wash K...
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#1Nader Shaikh (University of Pittsburgh)H-Index: 24
#2Judith M. Martin (University of Pittsburgh)H-Index: 19
Last. Timothy R. Shope (University of Pittsburgh)H-Index: 8
view all 20 authors...
Objective To determine whether treatment for urinary tract infections in children could be individualized using biomarkers for acute pyelonephritis. Study design We enrolled 61 children with febrile urinary tract infections, collected blood and urine samples, and performed a renal scan within 2 weeks of diagnosis to identify those with pyelonephritis. Renal scans were interpreted centrally by 2 experts. We measured inflammatory proteins in blood and urine using LUMINEX or an enzyme-linked immuno...
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#1Nader Shaikh (University of Pittsburgh)H-Index: 24
#2Alejandro Hoberman (University of Pittsburgh)H-Index: 38
Last. Timothy R. Shope (University of Pittsburgh)H-Index: 8
view all 8 authors...
Importance Accurately estimating the probability of urinary tract infection (UTI) in febrile preverbal children is necessary to appropriately target testing and treatment. Objective To develop and test a calculator (UTICalc) that can first estimate the probability of UTI based on clinical variables and then update that probability based on laboratory results. Design, Setting, and Participants Review of electronic medical records of febrile children aged 2 to 23 months who were brought to the eme...
6 CitationsSource
#1Judith M. Martin (University of Pittsburgh)H-Index: 19
#2Alejandro Hoberman (University of Pittsburgh)H-Index: 38
Last. Michael Green (University of Pittsburgh)H-Index: 53
view all 9 authors...
Background: In children with acute otitis media (AOM), a decrease in nasopharyngeal (NP) colonization with vaccine serotypes of Streptococcus pneumoniae has been noted since the introduction of pneumococcal conjugate vaccines (PCVs). The purpose of this study is to describe corresponding changes in colonization with Haemophilus influenzae. Methods: In 4 separate studies, we obtained NP cultures from children aged 6-23 months presenting with AOM. Cohort 1 was recruited before routine use of PCV7 ...
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#1Alejandro Hoberman (University of Pittsburgh)H-Index: 38
#2Jack L. Paradise (University of Pittsburgh)H-Index: 49
Last. Nader Shaikh (University of Pittsburgh)H-Index: 24
view all 18 authors...
Source
#1Alejandro Hoberman (University of Pittsburgh)H-Index: 38
#2Jack L. Paradise (University of Pittsburgh)H-Index: 49
Last. Nader Shaikh (University of Pittsburgh)H-Index: 24
view all 18 authors...
ABSTRACT Amoxicillin-clavulanate (A/C) is currently the most effective oral antimicrobial in treating children with acute otitis media (AOM), but the standard dosage of 90 mg amoxicillin/6.4 mg clavulanate/kg of body weight/day commonly causes diarrhea. We examined whether an A/C formulation containing lower concentrations of clavulanate would result in less diarrhea while maintaining plasma levels of amoxicillin and clavulanate adequate to eradicate middle-ear pathogens and to achieve clinical ...
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#1Timothy R. Shope (University of Pittsburgh)H-Index: 8
#2Benjamin H. Walker (MSU: Mississippi State University)H-Index: 2
Last. Judith M. Martin (University of Pittsburgh)H-Index: 19
view all 6 authors...
BACKGROUND: Children in child care centers represent an important population to consider in attempts to mitigate the spread of an influenza pandemic. This national survey, conducted in 2008 and 2016, assessed directors’ reports of their child care centers’ pandemic influenza preparation before and after the 2009 H1N1 novel influenza pandemic. METHODS: This was a telephone-based survey of child care center directors randomly selected from a national database of licensed US child care centers who ...
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