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Richard Wise
University of Nottingham
PsychologyAntibioticsMedicineBiologyMicrobiology
226Publications
41H-index
6,175Citations
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Publications 333
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#1Eve H. Limbrick-Oldfield (Imperial College London)H-Index: 1
#2Robert Leech (Imperial College London)H-Index: 41
Last. Mark A. Ungless (Imperial College London)H-Index: 25
view all 4 authors...
: Neurons in the ventral tegmental area (VTA) and substantia nigra pars compacta (SNC) play central roles in reward-related behaviours. Nonhuman animal studies suggest that these neurons also process aversive events. However, our understanding of how the human VTA and SNC responds to such events is limited and has been hindered by the technical challenge of using functional magnetic resonance imaging (fMRI) to investigate a small structure where the signal is particularly vulnerable to physiolog...
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#1Salwa Kamourieh (Imperial College London)H-Index: 3
#2Rodrigo M. Braga (Imperial College London)H-Index: 13
Last. Richard Wise (Imperial College London)H-Index: 41
view all 5 authors...
Background: An inability to recall recent conversations often indicates impaired episodic memory retrieval. It may also reflect a failure of attentive registration of spoken sentences which leads to unsuccessful memory encoding. The hypothesis was that patients complaining of impaired memory would demonstrate impaired function of ‘multiple demand’ (MD) brain regions, whose activation profile generalizes across cognitive domains, during speech registration in naturalistic listening conditions. Me...
1 CitationsSource
#1Magdalena W. Sliwinska (Imperial College London)H-Index: 4
#2Inês R. Violante (Imperial College London)H-Index: 13
Last. Adam Hampshire (Imperial College London)H-Index: 33
view all 7 authors...
It is well established that networks within multiple-demand cortex (MDC) become active when diverse skills and behaviors are being learnt. However, their causal role in learning remains to be established. In the present study, we first performed functional magnetic resonance imaging on healthy female and male human participants to confirm that MDC was most active in the initial stages of learning a novel vocabulary, consisting of pronounceable nonwords (pseudowords), each associated with a pictu...
6 CitationsSource
#1Rodrigo M. Braga (Imperial College London)H-Index: 13
#2Peter J. Hellyer (Imperial College London)H-Index: 18
Last. Robert Leech (Imperial College London)H-Index: 41
view all 4 authors...
A frontoparietal network of brain regions is often implicated in both auditory and visual information processing. Although it is possible that the same set of multimodal regions subserves both modalities, there is increasing evidence that there is a differentiation of sensory function within frontoparietal cortex. Magnetic reso- nance imaging (MRI) in humans was used to investigate whether different frontoparietal regions showed intrin- sic biases in connectivity with visual or auditory modaliti...
14 CitationsSource
#1Rodrigo M. Braga (Imperial College London)H-Index: 13
#2Richard Z. Fu (Imperial College London)H-Index: 4
Last. Robert Leech (Imperial College London)H-Index: 41
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The neural mechanisms supporting auditory attention are not fully understood. A dorsal frontoparietal network of brain regions is thought to mediate the spatial orienting of attention across all sensory modalities. Key parts of the this network, the frontal eye fields (FEF) and the superior parietal lobes (SPL), contain retinotopic maps and elicit saccades when stimulated. This suggests that their recruitment during auditory attention might reflect crossmodal oculomotor processes; however this h...
13 CitationsSource
#1Richard WiseH-Index: 41
#2Fatemeh GeranmayehH-Index: 12
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#1Richard Wise (Imperial College London)H-Index: 41
#2Fatemeh Geranmayeh (Imperial College London)H-Index: 12
The ability to speak is one of the most important functions that humans possess, and its loss as a consequence of brain disease is devastating. Therefore, it must rank as one of the most important functions to study using modern functional imaging techniques. However, artifacts generated during overt speech create problems. Further, it is not clear whether speech production can be addressed, from a functional–anatomical perspective, as an organization based on separate specialized linguistic mod...
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#1Salwa Kamourieh (Imperial College London)H-Index: 3
#2Rodrigo M. Braga (Imperial College London)H-Index: 13
Last. Richard Wise (Imperial College London)H-Index: 41
view all 6 authors...
Remembering what a speaker said depends on attention. During conversational speech, the emphasis is on working memory, but listening to a lecture encourages episodic memory encoding. With simultaneous interference from background speech, the need for auditory vigilance increases. We recreated these context-dependent demands on auditory attention in 2 ways. The first was to require participants to attend to one speaker in either the absence or presence of a distracting background speaker. The sec...
10 CitationsSource
#1Salwa Kamourieh (Imperial College London)H-Index: 3
#2Richard Wise (Imperial College London)H-Index: 41
Background Listening to one speaker in the presence of others (the ‘cocktail party’ problem) increases demands on attention and cognitive control. This study investigated the function of fronto-parietal systems and auditory regions in patients with progressive memory impairment. Methods Twenty-five healthy volunteers (controls) and 32 patients were studied with functional MRI. The task involved attending to a female speaker, either in the absence or the presence of a masking male speaker. Result...
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