Svante Pääbo
Max Planck Society
405Publications
121H-index
49.2kCitations
Publications 405
Newest
Martin Petr2
Estimated H-index: 2
(Max Planck Society),
Svante Pääbo121
Estimated H-index: 121
(Max Planck Society)
+ 1 AuthorsBenjamin Vernot19
Estimated H-index: 19
(Max Planck Society)
Several studies have suggested that introgressed Neandertal DNA was subjected to negative selection in modern humans. A striking observation in support of this is an apparent monotonic decline in Neandertal ancestry observed in modern humans in Europe over the past 45,000 years. Here, we show that this decline is an artifact likely caused by gene flow between modern human populations, which is not taken into account by statistics previously used to estimate Neandertal ancestry. When we apply a s...
2 Citations Source Cite
Published on Jan 30, 2019in Nature Communications 12.35
Thibaut Devièse9
Estimated H-index: 9
(University of Oxford),
Diyendo Massilani (Max Planck Society)+ 10 AuthorsB. Gunchinsuren4
Estimated H-index: 4
(Mongolian Academy of Sciences)
A skullcap found in the Salkhit Valley in northeast Mongolia is, to our knowledge, the only Pleistocene hominin fossil found in the country. It was initially described as an individual with possible archaic affinities, but its ancestry has been debated since the discovery. Here, we determine the age of the Salkhit skull by compound-specific radiocarbon dating of hydroxyproline to 34,950–33,900 Cal. BP (at 95% probability), placing the Salkhit individual in the Early Upper Paleolithic period. We ...
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Published on Jan 1, 2019in Current Biology 9.25
Philipp Gunz32
Estimated H-index: 32
(Max Planck Society),
Amanda K. Tilot2
Estimated H-index: 2
(Max Planck Society)
+ 24 AuthorsTulio Guadalupe13
Estimated H-index: 13
(Max Planck Society)
One of the features that distinguishes modern humans from our extinct relatives and ancestors is a globular shape of the braincase [1–4]. As the endocranium closely mirrors the outer shape of the brain, these differences might reflect altered neural architecture [4, 5]. However, in the absence of fossil brain tissue, the underlying neuroanatomical changes as well as their genetic bases remain elusive. To better understand the biological foundations of modern human endocranial shape, we turn to o...
2 Citations Source Cite
Published on Jan 1, 2019in Nature 41.58
Katerina Douka21
Estimated H-index: 21
(University of Oxford),
Viviane Slon11
Estimated H-index: 11
(Max Planck Society)
+ 18 AuthorsRainer Grün51
Estimated H-index: 51
(Griffith University)
Denisova Cave in the Siberian Altai (Russia) is a key site for understanding the complex relationships between hominin groups that inhabited Eurasia in the Middle and Late Pleistocene epoch. DNA sequenced from human remains found at this site has revealed the presence of a hitherto unknown hominin group, the Denisovans1,2, and high-coverage genomes from both Neanderthal and Denisovan fossils provide evidence for admixture between these two populations3. Determining the age of these fossils is im...
4 Citations Source Cite
Published on Feb 1, 2019in Antiquity 1.66
Katerina Douka21
Estimated H-index: 21
,
Samantha Brown3
Estimated H-index: 3
+ 3 AuthorsMichael V. Shunkov11
Estimated H-index: 11
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Published on Mar 1, 2018in Cell 31.40
Benjamin Vernot19
Estimated H-index: 19
(Max Planck Society),
Svante Pääbo121
Estimated H-index: 121
(Max Planck Society)
By examining the genomes of present-day people from Asia, researchers show that modern humans met and interbred with Denisovans, distant relatives to Neanderthals, on at least two occasions. As a result, people today carry DNA from two different Denisovan populations.
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Published on Dec 1, 2018in Nature Communications 12.35
Thiseas Christos Lamnidis3
Estimated H-index: 3
(Max Planck Society),
Kerttu Majander3
Estimated H-index: 3
(Max Planck Society)
+ 14 AuthorsAntje Weihmann6
Estimated H-index: 6
(Max Planck Society)
European population history has been shaped by migrations of people, and their subsequent admixture. Recently, ancient DNA has brought new insights into European migration events linked to the advent of agriculture, and possibly to the spread of Indo-European languages. However, little is known about the ancient population history of north-eastern Europe, in particular about populations speaking Uralic languages, such as Finns and Saami. Here we analyse ancient genomic data from 11 individuals f...
3 Citations Source Cite
Published on Mar 1, 2018in Nature 41.58
Mateja Hajdinjak9
Estimated H-index: 9
(Max Planck Society),
Qiaomei Fu21
Estimated H-index: 21
+ 28 AuthorsIsabelle Crevecoeur14
Estimated H-index: 14
Many questions remain about the relationship between populations of Neanderthals around the time of their final interactions with modern humans, and how this contributed to the evolution of modern humans. Janet Kelso, Svante Paabo and colleagues sequenced the genomes of five Neanderthals that lived between 39,000 and 47,000 years ago, broadening the temporal and geographical range of available Neanderthal genomes. They analyse these genomes together with previously sequenced ancient genomes and ...
19 Citations Source Cite
Published on May 4, 2018in Science 41.06
Marieke Sophia van de Loosdrecht1
Estimated H-index: 1
(Max Planck Society),
Abdeljalil Bouzouggar13
Estimated H-index: 13
(Max Planck Society)
+ 15 AuthorsMohammed Abdeljalil El Hajraoui6
Estimated H-index: 6
North Africa is a key region for understanding human history, but the genetic history of its people is largely unknown. We present genomic data from seven 15,000-year-old modern humans from Morocco, attributed to the Iberomaurusian culture. We find a genetic affinity with early Holocene Near Easterners, best represented by Levantine Natufians, suggesting a pre-agricultural connection between Africa and the Near East. We do not find evidence for gene flow from Paleolithic Europeans into Late Plei...
16 Citations Source Cite
Published on Apr 27, 2018in bioRxiv
Michael Dannemann15
Estimated H-index: 15
(Max Planck Society),
Benjamin Vernot19
Estimated H-index: 19
(Max Planck Society)
+ 2 AuthorsJ. Gray Camp6
Estimated H-index: 6
(Max Planck Society)
Pluripotent stem cells from diverse humans offer the potential to study human functional variation in controlled culture environments. A portion of this variation originates from ancient admixture between modern humans and Neandertals, which introduced alleles that left a phenotypic legacy on individual humans today. Here we show that a large repository of human induced pluripotent stem cells (iPSCs) harbors extensive Neandertal DNA, including most known functionally relevant Neandertal alleles ...
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