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Svante Pääbo
Max Planck Society
413Publications
122H-index
50.5kCitations
Publications 413
Newest
Published on Dec 1, 2019in Scientific Reports 4.01
Katarzyna Bozek12
Estimated H-index: 12
,
Ekaterina E. Khrameeva11
Estimated H-index: 11
+ 18 AuthorsPierrick Regnard1
Estimated H-index: 1
Published on Jan 30, 2019in Nature Communications 11.88
Thibaut Devièse10
Estimated H-index: 10
(University of Oxford),
Diyendo Massilani1
Estimated H-index: 1
(MPG: Max Planck Society)
+ 10 AuthorsB. Gunchinsuren4
Estimated H-index: 4
(Mongolian Academy of Sciences)
A skullcap found in the Salkhit Valley in northeast Mongolia is, to our knowledge, the only Pleistocene hominin fossil found in the country. It was initially described as an individual with possible archaic affinities, but its ancestry has been debated since the discovery. Here, we determine the age of the Salkhit skull by compound-specific radiocarbon dating of hydroxyproline to 34,950–33,900 Cal. BP (at 95% probability), placing the Salkhit individual in the Early Upper Paleolithic period. We ...
Published in Nucleic Acids Research 11.15
Stephan Riesenberg2
Estimated H-index: 2
(MPG: Max Planck Society),
Manjusha Chintalapati2
Estimated H-index: 2
(MPG: Max Planck Society)
+ -3 AuthorsSvante Pääbo122
Estimated H-index: 122
(MPG: Max Planck Society)
Lukas Bokelmann (MPG: Max Planck Society), Mateja Hajdinjak10
Estimated H-index: 10
(MPG: Max Planck Society)
+ 14 AuthorsSarah Nagel8
Estimated H-index: 8
(MPG: Max Planck Society)
The Forbes’ Quarry and Devil’s Tower partial crania from Gibraltar are among the first Neanderthal remains ever found. Here, we show that small amounts of ancient DNA are preserved in the petrous bones of the 2 individuals despite unfavorable climatic conditions. However, the endogenous Neanderthal DNA is present among an overwhelming excess of recent human DNA. Using improved DNA library construction methods that enrich for DNA fragments carrying deaminated cytosine residues, we were able to se...
Published on Jun 27, 2019in bioRxiv
Sabina Kanton3
Estimated H-index: 3
(MPG: Max Planck Society),
Michael James Boyle (MPG: Max Planck Society)+ 14 AuthorsDingding Han3
Estimated H-index: 3
(CAS-MPG Partner Institute for Computational Biology)
The human brain has changed dramatically since humans diverged from our closest living relatives, chimpanzees and the other great apes. However, the genetic and developmental programs underlying this divergence are not fully understood. Here, we have analyzed stem cell-derived cerebral organoids using single-cell transcriptomics (scRNA-seq) and accessible chromatin profiling (scATAC-seq) to explore gene regulatory changes that are specific to humans. We first analyze cell composition and reconst...
Published on Jun 1, 2019in Science Advances
Stéphane Peyrégne3
Estimated H-index: 3
(MPG: Max Planck Society),
Viviane Slon12
Estimated H-index: 12
(MPG: Max Planck Society)
+ 19 AuthorsKurt Wehrberger3
Estimated H-index: 3
Little is known about the population history of Neandertals over the hundreds of thousands of years of their existence. We retrieved nuclear genomic sequences from two Neandertals, one from Hohlenstein-Stadel Cave in Germany and the other from Scladina Cave in Belgium, who lived around 120,000 years ago. Despite the deeply divergent mitochondrial lineage present in the former individual, both Neandertals are genetically closer to later Neandertals from Europe than to a roughly contemporaneous in...
Published on Mar 1, 2019
Bence Viola15
Estimated H-index: 15
,
Philipp Gunz34
Estimated H-index: 34
(MPG: Max Planck Society)
+ 6 AuthorsA.P. Derevianko14
Estimated H-index: 14
Published on Feb 1, 2019in Antiquity 1.47
Katerina Douka22
Estimated H-index: 22
(MPG: Max Planck Society),
Samantha Brown3
Estimated H-index: 3
+ 3 AuthorsMichael V. Shunkov12
Estimated H-index: 12
Martin Petr3
Estimated H-index: 3
(MPG: Max Planck Society),
Svante Pääbo122
Estimated H-index: 122
(MPG: Max Planck Society)
+ 1 AuthorsBenjamin Vernot19
Estimated H-index: 19
(MPG: Max Planck Society)
Several studies have suggested that introgressed Neandertal DNA was subjected to negative selection in modern humans. A striking observation in support of this is an apparent monotonic decline in Neandertal ancestry observed in modern humans in Europe over the past 45,000 years. Here, we show that this decline is an artifact likely caused by gene flow between modern human populations, which is not taken into account by statistics previously used to estimate Neandertal ancestry. When we apply a s...
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