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Mustafa Raoof
City of Hope National Medical Center
CancerSurgeryPathologyGeneral surgeryMedicine
72Publications
9H-index
172Citations
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Publications 71
Newest
#1Shanna J. Smith (City of Hope National Medical Center)
#1Shanna J. SmithH-Index: 3
Last. Mustafa Raoof (City of Hope National Medical Center)H-Index: 9
view all 7 authors...
Pancreatic ductal adenocarcinoma is a particularly difficult cancer to treat due to a lack of effective screening or treatment. Pancreatic cancer cells exhibit high proliferating cell nuclear antigen (PCNA) expression, which is associated with poor prognosis. PCNA, an important nuclear DNA replication and repair protein, regulates a myriad of proteins via the interdomain connector loop. Within this region, amino acids 126-133 are critical for PCNA interactions in cancer cells. Here, we investiga...
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#1Ioannis T. Konstantinidis (Texas Tech University Health Sciences Center at El Paso)
#2Byrne Lee (City of Hope National Medical Center)H-Index: 9
Last. Mustafa Raoof (City of Hope National Medical Center)H-Index: 9
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BACKGROUND AND OBJECTIVES Studies reporting outcomes after pelvic exenteration for rectal cancer are limited. The objective of this study was to evaluate early postoperative and oncologic outcomes in a national multi-institutional cohort. METHODS Using the National Cancer Database (NCDB), which collects data from over 1500 commission on cancer (CoC)-accredited hospitals, we analyzed patients undergoing pelvic exenteration for T4b rectal adenocarcinoma. RESULTS There were 1367 pelvic exenteration...
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#1Ioannis Konstantinidis (City of Hope National Medical Center)H-Index: 22
#2Mustafa Raoof (City of Hope National Medical Center)H-Index: 9
Last. Byrne Lee (City of Hope National Medical Center)H-Index: 9
view all 7 authors...
The application of robotic technology allows for the performance of multi-organ liver resections by multidisciplinary teams in a minimally invasive manner. Their technique and outcomes are not established. Herein we describe our technique with robotic liver surgery combined with colon, pancreas and urologic resections. Our patients are an 84-year-old (yo) female (Body Mass Index, BMI: 25) with a recently diagnosed right colon adenocarcinoma and two synchronous liver metastases at segments 5 and ...
1 CitationsSource
#1Thanh H. Dellinger (City of Hope National Medical Center)H-Index: 11
#2Xiwei Wu (Beckman Research Institute)H-Index: 39
Last. Mihaela C. Cristea (City of Hope National Medical Center)H-Index: 17
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#1Michael K. Turgeon (Emory University)H-Index: 1
#2Adriana C. Gamboa (Emory University)H-Index: 2
Last. Jula Veerapong (UCSD: University of California, San Diego)H-Index: 8
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BACKGROUND: Patient age is a significant factor in preoperative selection for major abdominal surgery. The association of age, tumor biology, and postoperative outcomes in patients undergoing cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) remains ill-defined. METHODS: Retrospective analysis was performed for patients who underwent a CCR0/1 CRS/HIPEC from the US HIPEC Collaborative Database (2000-2017). Age was categorized into /= 65 years. Primary outcome was p...
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#1Benjamin PowersH-Index: 2
#1Benjamin D. PowersH-Index: 5
Last. Vikrom K. Dhar (University of Cincinnati Academic Health Center)H-Index: 9
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BACKGROUND: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is offered to select patients with peritoneal metastases. In instances of recurrence/progression, a repeat CRS/HIPEC may be considered. The perioperative morbidity and the potential oncologic benefits are not well described. PATIENTS AND METHODS: We performed a retrospective analysis of a multiinstitutional database to assess the perioperative outcomes following repeat CRS/HIPEC (repeat). Kaplan-Meier and...
1 CitationsSource
#1Andrew M. Blakely (City of Hope National Medical Center)H-Index: 2
#2Kelly J. Lafaro (City of Hope National Medical Center)H-Index: 6
Last. Mustafa Raoof (City of Hope National Medical Center)H-Index: 9
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Abstract Background Primary tumor location has emerged as an important surrogate for tumor biology in metastatic colorectal cancer treated with systemic chemotherapy. It is unclear if primary tumor location is associated with survival after cytoreductive surgery (CRS) with or without heated intraperitoneal chemotherapy (HIPEC) for colorectal carcinomatosis. Methods Study of a contemporary cohort merged data from the California Cancer Registry, 2004-2012, and the Office of Statewide Health Planni...
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#1Eliza W. Beal (The Ohio State University Wexner Medical Center)H-Index: 16
#2Lorena P. Suarez-Kelly (The Ohio State University Wexner Medical Center)H-Index: 5
Last. Travis E. Grotz (Mayo Clinic)H-Index: 15
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Cytoreductive surgery (CRS) with or without hyperthermic intraperitoneal chemotherapy (HIPEC) is associated with improved survival for patients with colorectal peritoneal metastases (CR-PM). However, the role of neoadjuvant chemotherapy (NAC) prior to CRS-HIPEC is poorly understood. A retrospective review of adult patients with CR-PM who underwent CRS+/-HIPEC from 2000–2017 was performed. Among 298 patients who underwent CRS+/-HIPEC, 196 (65.8%) received NAC while 102 (34.2%) underwent surgery f...
1 CitationsSource
#1Eliza W. Beal (The Ohio State University Wexner Medical Center)H-Index: 16
#2Ahmed Ahmed (The Ohio State University Wexner Medical Center)H-Index: 2
Last. Jordan M. Cloyd (The Ohio State University Wexner Medical Center)H-Index: 9
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Abstract Background Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is an increasingly utilized strategy for patients with peritoneal surface malignancies (PSM). Methods The US HIPEC Collaborative was retrospectively reviewed to compare the indications and perioperative outcomes of patients who underwent CRS ± HIPEC between 2000 and 2012 (P1) versus 2013–2017 (P2). Results Among 2,364 patients, 39% were from P1 and 61% from P2. The most common primary site was ...
3 CitationsSource
#1Jason T. Wiseman (OSU: Ohio State University)H-Index: 9
#1Jason T. Wiseman (OSU: Ohio State University)H-Index: 1
Last. Jordan M. Cloyd (OSU: Ohio State University)H-Index: 9
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Background Anastomotic failure (AF) after cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) remains a dreaded complication. Whether specific factors, including anastomotic technique, are associated with AF is poorly understood.
3 CitationsSource
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