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Caterina Mammi
University of Modena and Reggio Emilia
EndocrinologyAdipose tissueImmunologyMedicineBiology
70Publications
18H-index
1,182Citations
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Publications 71
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Atherosclerosis is a progressive vascular disease representing the primary cause of morbidity and mortality in developed countries. Formerly, atherosclerosis was considered as a mere passive accumulation of lipids in blood vessels. However, it is now clear that atherosclerosis is a complex and multifactorial disease, in which the involvement of immune cells and inflammation play a key role. A variety of studies have shown that autophagy-a cellular catalytic mechanism able to remove injured cytop...
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#1Francesco MerliH-Index: 29
#2Federica Cavallo (UNITO: University of Turin)H-Index: 51
Last. Stefano Luminari (University of Modena and Reggio Emilia)H-Index: 38
view all 20 authors...
ABSTRACT Objective To evaluate activity and safety of obinutuzumab-miniCHOP (Ga101-miniCHOP) combination in older patients with Diffuse Large B-Cell Lymphoma (DLBCL) unfit to receive full dose immunochemotherapy. Materials and Methods We conducted a Simon's two-stage phase II multicenter trial to investigate response rate (primary endpoint) and safety of six courses of Ga101-miniCHOP in older patients with DLBCL (≥65 years), prospectively defined as unfit according to a simplified Comprehensive ...
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#1Michele SpinaH-Index: 38
#2Francesco Merli (AUSL: Academy for Urban School Leadership)H-Index: 29
Last. Alessandra TucciH-Index: 26
view all 36 authors...
1 CitationsSource
#1Andrea ArmaniH-Index: 12
#2Vincenzo MarzollaH-Index: 9
Last. Massimiliano CaprioH-Index: 25
view all 7 authors...
Source
#1Stefania GoriniH-Index: 1
#1Stefania GoriniH-Index: 8
Last. Massimiliano Caprio (OU: Open University)H-Index: 25
view all 8 authors...
The mineralocorticoid receptor (MR) was originally identified as a regulator of blood pressure, able to modulate renal sodium handling in response to its principal ligand aldosterone. MR is also expressed in many tissues other than kidney, including the heart, vasculature and adipose tissue. More recent studies have shown that extra-renal MR plays a relevant role in the control of cardiovascular and metabolic functions and has recently been implicated in the pathophysiology of aging. MR activati...
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#1Michele SpinaH-Index: 22
#2Francesco MerliH-Index: 29
Last. A. TucciH-Index: 8
view all 35 authors...
Source
#1Vincenzo MarzollaH-Index: 9
#2Andrea M. ArmaniH-Index: 20
Last. Massimiliano Caprio (OU: Open University)H-Index: 25
view all 5 authors...
Atherosclerosis is due to a chronic inflammatory response affecting vascular endothelium and is promoted by several factors such as hypertension, dyslipidemia, and diabetes. To date, there is evidence to support a role for circulating aldosterone as a risk factor for the development of cardiovascular disease. Transgenic mouse models have been generated to study cellular and molecular processes leading to atherosclerosis. In this manuscript, we describe a protocol that takes advantage of continuo...
2 CitationsSource
#1Stefania GoriniH-Index: 8
#2Vincenzo MarzollaH-Index: 9
Last. Massimiliano CaprioH-Index: 25
view all 5 authors...
The mineralocorticoid receptor (MR) was first identified as a blood pressure regulator, modulating renal sodium handling in response to its principal ligand aldosterone. The mineralocorticoid receptor is also expressed in many tissues other than the kidney, such as adipose tissue, heart and vasculature. Recent studies have shown that MR plays a relevant role in the control of cardiovascular and metabolic function, as well as in adipogenesis. Dysregulation of aldosterone/MR signaling represents a...
3 CitationsSource
#1Marco InfanteH-Index: 2
#2Andrea ArmaniH-Index: 12
Last. Massimiliano Caprio (OU: Open University)H-Index: 25
view all 5 authors...
10 CitationsSource
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