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Bryan Cwik
Portland State University
4Publications
2H-index
15Citations
Publications 4
Newest
#1Bryan Cwik (PSU: Portland State University)H-Index: 2
Design of clinical trials for germline gene editing stretches current accepted standards for human subjects research. Among the challenges involved is a set of issues concerning intergenerational monitoring—long-term follow-up study of subjects and their descendants. Because changes made at the germline would be heritable, germline gene editing could have adverse effects on individuals’ health that can be passed on to future generations. Determining whether germline gene editing is safe and effe...
With gene-editing technology advancing rapidly, it is important to consider the ethical issues it raises for research, including those related to intergenerational monitoring — long-term follow-up monitoring of not just trial participants, but also their descendants.
#1Douglas L. Bessette (OSU: Ohio State University)H-Index: 5
#2Lauren A. Mayer (AN: RAND Corporation)H-Index: 5
Last.Nancy Tuana (PSU: Pennsylvania State University)H-Index: 18
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Individuals use values to frame their beliefs and simplify their understanding when confronted with complex and uncertain situations. The high complexity and deep uncertainty involved in climate risk management (CRM) lead to individuals’ values likely being coupled to and contributing to their understanding of specific climate risk factors and management strategies. Most mental model approaches, however, which are commonly used to inform our understanding of people's beliefs, ignore values. In...
#1Lauren A. Mayer (AN: RAND Corporation)H-Index: 5
#2Kathleen Loa (AN: RAND Corporation)H-Index: 1
Last.Robert J. Lempert (AN: RAND Corporation)H-Index: 34
view all 8 authors...
Abstract When developing computational models to analyze the tradeoffs between climate risk management strategies (i.e., mitigation, adaptation, or geoengineering), scientists make explicit and implicit decisions that are influenced by their beliefs, values and preferences. Model descriptions typically include only the explicit decisions and are silent on value judgments that may explain these decisions. Eliciting scientists’ mental models, a systematic approach to determining how they think abo...
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