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Andrés Cárdenas
University of Barcelona
113Publications
22H-index
2,536Citations
Publications 113
Newest
#1Andres Cardenas (University of California, Berkeley)H-Index: 17
#2Joanne E. Sordillo (Harvard University)H-Index: 18
Last.Juan C. Celedón (University of Pittsburgh)H-Index: 57
view all 16 authors...
The nasal cellular epigenome may serve as biomarker of airway disease and environmental response. Here we collect nasal swabs from the anterior nares of 547 children (mean-age 12.9 y), and measure DNA methylation (DNAm) with the Infinium MethylationEPIC BeadChip. We perform nasal Epigenome-Wide Association analyses (EWAS) of current asthma, allergen sensitization, allergic rhinitis, fractional exhaled nitric oxide (FeNO) and lung function. We find multiple differentially methylated CpGs (FDR < 0...
#1Andrés Cárdenas (University of California, Berkeley)H-Index: 22
#2Sharon M. Lutz (Harvard University)H-Index: 18
Last.Marie-France Hivert (Harvard University)H-Index: 36
view all 6 authors...
#1Andres Cardenas (University of California, Berkeley)H-Index: 17
#2Marie-France Hivert (Harvard University)H-Index: 36
Last.Thomas F. Webster (BU: Boston University)H-Index: 35
view all 12 authors...
OBJECTIVE Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are suspected endocrine disruptors widely detected across populations. We examine the extent to which PFASs are associated with diabetes incidence and microvascular disease. Secondarily, we tested whether a lifestyle intervention modifies associations and decreases concentrations. RESEARCH DESIGN AND METHODS We analyzed data from a prospective cohort of 957 participants from the Diabetes Prevention Program (DPP) trial and Outcomes S...
#1Todd M. Everson (Emory University)H-Index: 8
Last.Barbara Heude (Paris V: Paris Descartes University)H-Index: 33
view all 34 authors...
Maternal smoking during pregnancy (MSDP) contributes to poor birth outcomes, in part through disrupted placental functions, which may be reflected in the placental epigenome. We meta-analyzed the associations between MSDP and placental DNA methylation (DNAm) and between DNAm and birth outcomes within the Pregnancy And Childhood Epigenetics (PACE) consortium (7 studies, N=1700, 344 with any MSDP). We identified 1224 CpGs that were associated with MSDP, of which 341 associated with birth outcomes ...
#1Cheng Peng (Brigham and Women's Hospital)H-Index: 3
#2Andres Cardenas (Harvard University)H-Index: 17
Last.Juan C. Celedón (University of Pittsburgh)H-Index: 57
view all 14 authors...
Background Epigenetic clocks have been suggested to capture one feature of the complexity between aging and the epigenome. However, little is known about the epigenetic clock in childhood allergy and asthma. Objective We sought to examine associations of DNA methylation age (DNAmAge) and epigenetic age acceleration with childhood allergy and asthma. Methods We calculated DNAmAge and age acceleration at birth, early childhood, and midchildhood based on the IlluminaHumanMethylation450BeadChip in P...
#1S. Rodrigues (University of Bern)H-Index: 1
#2Andrés Cárdenas (University of Barcelona)H-Index: 22
Last.Jaime Bosch (University of Bern)H-Index: 7
view all 4 authors...
Failure to control variceal bleeding with current recommendations occurs in 10 to 20% of cases. This systematic review and meta-analysis analyzes the experience, results, and complications of “bridge” therapies for failure to control acute variceal bleeding: balloon tamponade and esophageal stents. The main outcomes assessed were failure to control bleeding and mortality in the short-term and medium-term follow-up, and adverse events. Balloon tamponade studies had a pooled rate of short-term fai...
#1Erik L. Lum (UCLA: University of California, Los Angeles)H-Index: 6
#2Andrés Cárdenas (University of Barcelona)H-Index: 22
Last.Suphamai Bunnapradist (UCLA: University of California, Los Angeles)H-Index: 41
view all 4 authors...
#2Cheng Peng (Brigham and Women's Hospital)H-Index: 3
Last.Katherine Svensson (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 10
view all 21 authors...
Abstract Introduction Lead (Pb) crosses the placenta and can cause oxidative stress, reduced fetal growth and neurological problems. The principal source of oxidative stress in human cells is mitochondria. Therefore, disruption of normal mitochondrial function during pregnancy may represent a primary mechanism behind the adverse effects of lead. We sought to assess the association of Pb exposure during pregnancy with mitochondrial DNA (mtDNA) content, a sensitive marker of mitochondrial function...
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