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J. T. Moller
Copenhagen University Hospital
40Publications
20H-index
4,304Citations
Publications 40
Newest
#1Signe Møller-Bisgaard (Copenhagen University Hospital)H-Index: 4
#2Kim Hørslev-Petersen (University of Southern Denmark)H-Index: 31
Last.Mikkel Østergaard (Copenhagen University Hospital)H-Index: 75
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Background Rheumatoid arthritis (RA) is a chronic, progressive joint disease, which frequently leads to irreversible joint deformity and severe functional impairment. Although patients are treated according to existing guidelines and reach clinical remission, erosive progression still occurs. This demonstrates that additional methods for prognostication and monitoring of the disease activity are needed. Bone marrow edema (BME) detected by magnetic resonance imaging (MRI) has proved to be an inde...
6 CitationsSource
#1Uffe Møller Døhn (Copenhagen University Hospital)H-Index: 15
#2Lene Terslev (Copenhagen University Hospital)H-Index: 31
Last.Mikkel Østergaard (Copenhagen University Hospital)H-Index: 75
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Objectives To determine the accuracy of ultrasonography (US) for bone erosion detection in different areas of rheumatoid arthritis (RA) metacarpophalangeal (MCP) joints with multislice CT as the reference method. Second, to establish the necessary bone volume loss on CT for US to reliably detect it as an erosion, and finally to compare two semiquantitative US-erosion scoring methods. Methods The 2nd–5th MCP joints of 49 patients with RA were examined by CT and US, and evaluated for the presence ...
28 CitationsSource
#1Lars S. RasmussenH-Index: 1
#2Bjørn SperlingH-Index: 1
Last.J. T. MollerH-Index: 20
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#1Uffe Møller Døhn (Copenhagen University Hospital)H-Index: 15
#2Bo Ejbjerg (Copenhagen University Hospital)H-Index: 26
Last.Mikkel Østergaard (Copenhagen University Hospital)H-Index: 75
view all 7 authors...
Background The objectives of the present study were, with multidetector computed tomography (CT) as the reference method, to determine the performance of magnetic resonance imaging (MRI) and radiography for the detection of bone erosions in rheumatoid arthritis wrist bones, and to test whether measuring volumes of erosions on CT and MRI is reproducible and correlated to semiquantitative assessments (scores) of erosions on CT, MRI and radiography.
112 CitationsSource
#1L.S. Rasmussen (Copenhagen University Hospital)H-Index: 52
#2John T. O'BrienH-Index: 101
Last.J. T. Moller (Copenhagen University Hospital)H-Index: 20
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Background: The pattern of cortisol secretion is influenced by surgery. As cortisol can adversely affect neuronal function, this may be an important factor in the development of post-operative cognitive dysfunction (POCD). We hypothesized that the incidence of POCD would be related to changes in cortisol level. Methods: We studied 187 patients aged over 60 years undergoing major non-cardiac surgery with general or regional anaesthesia. Saliva cortisol levels were measured pre-operatively and at ...
65 CitationsSource
#1Henrik S. Thomsen (Copenhagen University Hospital)H-Index: 54
#2Vibeke Loegager (Copenhagen University Hospital)H-Index: 2
Last.Jesper Sonne (Copenhagen University Hospital)H-Index: 5
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The study population included 12 healthy male volunteers (mean age: 24.9 years range: 20 39). All underwent abdominal MR imaging (T2W COR, T1W COR, T1W TRA) in both a Panorama 0.23T-V MR unit, a Panorama 0.6T-V MR unit and an Infinion 1.5 T-H MR unit (all Philip Medical Systems, Best, the Netherlands) after randomization. The total examination time in the three units was 2 hours, so 40 min after start of the first examination they switched to another MR-unit and 40 min later the volunteers start...
7 CitationsSource
#1C. SkakH-Index: 1
#2L.S. RasmussenH-Index: 52
Last.J. T. MollerH-Index: 20
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#2Lasse Dam Rasmussen (DTU: Technical University of Denmark)H-Index: 16
Last.J. T. MollerH-Index: 20
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The experiments show that composting of GM plant residues greatly increases the rate of degradation of transgenic DNA compared to the rate for plant residues left in the soil. If the persistence of transgenic DNA in the environments is considered as the only risk factor, composting is a 'DNA-safe' method to treat GM plant residues. However, even though transgenic plant DNA was not detected in bacterial isolates in our experiments, we cannot conclude that horizontal gene transfer can not take pla...
#1Jaume CanetH-Index: 20
#2J RaederH-Index: 3
Last.J. T. Moller (Copenhagen University Hospital)H-Index: 20
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Keywords:General anesthesia;minor surgery;out-patient surgery;cognitive dysfunction Background: Major surgery is frequently associated with postoperative cognitive dysfunction (POCD) in elderly patients. Type of surgery and hospitalization may be important prognostic factors. The aims of the study were to find the incidence and risk factors for POCD in elderly patients undergoing minor surgery. Methods: We enrolled 372 patients aged greater than 60 years scheduled for minor surgery under general...
217 CitationsSource
#1L.S. Rasmussen (Copenhagen University Hospital)H-Index: 52
#2T Johnson (University of Salford)H-Index: 5
Last.J. T. Moller (Copenhagen University Hospital)H-Index: 20
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Results: At 7 days, POCD was found in 37/188 patients (19.7%, [14.3—26.1%]) after general anaesthesia and in 22/176 (12.5%, [8.0—18.3%]) after regional anaesthesia, P ¼ 0.06. After 3 months, POCD was present in 25/175 patients (14.3%, [9.5—20.4%]) after general anaesthesia vs. 23/165 (13.9%, [9.0—20.2%]) after regional anaesthesia, P ¼ 0.93. The incidence of POCD after 1 week was significantly greater after general anaesthesia when we excluded patients who did not receive the allocated anaesthet...
405 CitationsSource
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