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Laura Valerio
University of Pisa
EndocrinologyCarcinomaThyroid cancerMedullary thyroid cancerMedicine
20Publications
6H-index
345Citations
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Publications 23
Newest
#1Laura ValerioH-Index: 6
#2Valeria BotticiH-Index: 18
Last. Rossella EliseiH-Index: 66
view all 13 authors...
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#1Antonio MatroneH-Index: 7
#2Carla GambaleH-Index: 1
Last. Rossella EliseiH-Index: 66
view all 13 authors...
Abstract Objective: In intermediate risk DTC (IR-DTC) patients, selective use of radioiodine (131-I) for remnant ablation and/or as adjuvant therapy (RRA) is advocated. The recently suggested post-...
Source
CONTEXT: The dramatic rise in the incidence of thyroid cancer over the last 30 years is largely attributable to the increasing diagnosis of papillary microcarcinomas (mPTCs). Current guidelines endorse an observational management approach in properly selected cases. OBJECTIVE: To evaluate the feasibility of active surveillance in mPTC in Italy, its impact on real life, and to identify risk factors of progression. DESIGN AND SETTING: In 2014 we started a prospective-observational study of active ...
2 CitationsSource
#1Rossella EliseiH-Index: 66
#2Alessia TacitoH-Index: 8
Last. Cristina RomeiH-Index: 37
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Background: Pathogenic germline mutations affecting the RET proto-oncogene underlie the development of hereditary medullary thyroid carcinoma (MTC). The aims of this study were to evaluate the prevalence of germline RET mutations in a large series of MTC, collected over the last 25 years, and to reappraise their clinical significance. Methods: We performed RET genetic screening in 2031 Italian subjects: patients who presented with sporadic (n = 1264) or hereditary (n = 117) MTC, plus 650 relativ...
1 CitationsSource
#1Rossella Elisei (UniPi: University of Pisa)H-Index: 66
#2Antonio Matrone (UniPi: University of Pisa)H-Index: 7
Last. Cristina Romei (UniPi: University of Pisa)H-Index: 37
view all 15 authors...
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#1Laura ValerioH-Index: 6
#2Valeria BotticiH-Index: 18
Last. Rossella EliseiH-Index: 2
view all 7 authors...
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#1Antonio MatroneH-Index: 7
#2Carla GambaleH-Index: 1
Last. Rossella EliseiH-Index: 2
view all 8 authors...
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#1Frederic Castinetti (AMU: Aix-Marseille University)H-Index: 24
#2Steven G Waguespack (University of Texas System)H-Index: 1
Last. Eric Baudin ('ENS Paris': École Normale Supérieure)H-Index: 1
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Summary Background Multiple endocrine neoplasia type 2B is a rare syndrome caused mainly by Met918Thr germline RET mutation, and characterised by medullary thyroid carcinoma, phaeochromocytoma, and extra-endocrine features. Data are scarce on the natural history of multiple endocrine neoplasia type 2B. We aimed to advance understanding of the phenotype and natural history of multiple endocrine neoplasia type 2B, to increase awareness and improve detection. Methods This study was a retrospective,...
5 CitationsSource
Abstract Follicular Variant of Papillary Thyroid Carcinoma (FVPTC) is usually associated with a good outcome. Nevertheless, in rare cases, it develops distant metastases (1–9%). Our goal was to investigate whether mRNA and miRNA expression profiles may help distinguish between metastatic versus non-metastatic FVPTCs. Twenty-four primary FVPTCs, 12 metastatic and 12 non-metastatic, with similar clinicopathological features were selected and analyzed by nanoString nCounter technology using two dis...
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#1Carlotta GianiH-Index: 6
#2Laura ValerioH-Index: 6
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