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Clare C. Yu
University of California, Irvine
PhysicsPhase transitionCondensed matter physicsNuclear magnetic resonanceSuperconductivity
124Publications
17H-index
1,435Citations
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Publications 119
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We present a novel view of the standard model of tunneling two level systems (TLSs) to explain the puzzling universal value of a quantity, C approximately 3x10^{-4}, that characterizes phonon scattering in glasses below 1 K as reflected in thermal conductivity, ultrasonic attenuation, internal friction, and the change in sound velocity. Physical considerations lead to a broad distribution of phonon-TLS couplings that (1) exponentially renormalize tunneling matrix elements, and (2) reduce the TLS...
1 CitationsSource
#1Clare C. Yu (UCI: University of California, Irvine)H-Index: 17
#2Juliana C. WortmanH-Index: 2
Last. Peter P. LeeH-Index: 42
view all 15 authors...
The goal of immunotherapy is to enhance the ability of the immune system to kill cancer cells. Immunotherapy is more effective and, in general, the prognosis is better, when more immune cells infiltrate the tumor. We explore the question of whether the spatial distribution rather than just the density of immune cells in the tumor is important in forecasting whether cancer recurs. After reviewing previous work on this issue, we introduce a novel application of maximum entropy to quantify the spat...
#1Juliana C. Wortman (UCI: University of California, Irvine)H-Index: 2
#2Ting-Fang He (Beckman Research Institute)H-Index: 6
Last. Clare C. Yu (UCI: University of California, Irvine)H-Index: 17
view all 15 authors...
While the density of tumor-infiltrating lymphocytes (TILs) is now well known to correlate with clinical outcome, the clinical significance of spatial distribution of TILs is not well characterized. We have developed novel statistical techniques (including fractal dimension differences, a hotspot analysis, a box counting method that we call 9occupancy9 and a way to normalize cell density that we call 9thinning9) to analyze the spatial distribution (at different length scales) of various types of ...
Source
#1Zhe WangH-Index: 4
#2Hui WangH-Index: 24
Last. Ruqian WuH-Index: 41
view all 4 authors...
Superconducting qubits are hampered by flux noise produced by surface spins from a variety of microscopic sources. Recent experiments indicated that hydrogen (H) atoms may be one of those sources. Using density functional theory calculations, we report that H atoms either embedded in, or adsorbed on, an a-Al2O3(0001) surface have sizeable spin moments ranging from 0.81 to 0.87 uB with energy barriers for spin reorientation as low as ~10 mK. Furthermore, H adatoms on the surface attract gas molec...
3 CitationsSource
#1Ruqian WuH-Index: 41
#2Zhe WangH-Index: 4
Last. Clare C. YuH-Index: 17
view all 4 authors...
#1Clare C. Yu (UCI: University of California, Irvine)H-Index: 17
#2James K. Mitchell (Harvard University)H-Index: 2
Why does a tumor start where it does within an organ? Location is traditionally viewed as a random event, yet the statistics of the location of tumors argues against this being a random occurrence. There are numerous examples including that of breast cancer. More than half of invasive breast cancer tumors start in the upper outer quadrant of the breast near the armpit, even though it is estimated that only 35 to 40% of breast tissue is in this quadrant. This suggests that there is an unknown mic...
2 CitationsSource
#1Zhe WangH-Index: 4
#2Hui WangH-Index: 8
Last. Ruqian WuH-Index: 41
view all 4 authors...
Superconducting qubits are hampered by flux noise produced by surface spins from a number of sources. Recent experiments indicated that hydrogen (H) atoms may be one of the sources. Using density functional theory calculations, we report that H atoms either embedded in or adsorbed on an {\alpha}-Al2O3(0001) surface have sizeable spin moments ranging from 0.81 to 0.87 {\mu}B with extremely shallow energy barriers for spin reorientation as low as ~10 mK. Furthermore, H adatoms on the surface attra...
1 Citations
#1Juliana C. Wortman (UCI: University of California, Irvine)H-Index: 2
#2Marcos Nahmad (UCI: University of California, Irvine)H-Index: 5
Last. Clare C. Yu (UCI: University of California, Irvine)H-Index: 17
view all 5 authors...
In developing tissues, cell polarization and proliferation are regulated by morphogens and signaling pathways. Cells throughout the Drosophila wing primordium typically show subcellular localization of the unconventional myosin Dachs on the distal side of cells (nearest the center of the disc). Dachs localization depends on the spatial distribution of bonds between the protocadherins Fat (Ft) and Dachsous (Ds), which form heterodimers between adjacent cells; and the Golgi kinase Four-jointed (Fj...
2 CitationsSource
#1Zhe WangH-Index: 4
#2Hui WangH-Index: 24
Last. Ruqian WuH-Index: 41
view all 4 authors...
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