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Franz Bucar
University of Graz
153Publications
28H-index
3,753Citations
Publications 154
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#1Sandra Ochensberger (University of Graz)
#2Fabian Alperth (University of Graz)H-Index: 1
Last.Franz Bucar (University of Graz)H-Index: 28
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Little is known about the pharmacological activities of Iris adriatica (Iridaceae), a plant en-demic to Dalmatia (Croatia). For this purpose, we performed a bioassay-guided fractionation including high-performance counter current chromatography (HPCCC) and antibacterial tests using Mycobacterium smegmatis mc² 155. One obtained fraction was found to be antimyco-bacterially active with a MIC of 64 mg L-1. Furthermore, fractions were tested for resistance modulatory effects using ethidium bromide a...
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#1Marija Kindl (University of Zagreb)H-Index: 5
#2Franz Bucar (University of Graz)H-Index: 28
Last.Sanda Vladimir-Knežević (University of Zagreb)H-Index: 14
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The polyphenolic composition and anti-inflammatory activity of selected Thymus species (T. longicaulis C. Presl, T. praecox Opiz subsp. polytrichus (A. Kerner Ex Borbas) Jalas, T. pulegioides L., T. serpyllum L. subsp. serpyllum and T. striatus Vahl) was studied in comparison with T. vulgaris, as an officinal medicinal plant, to evaluate the biomedical potential of these Croatian wild-growing species. This paper provides a first insight into the polyphenolic profiles of T. praecox subsp. polytri...
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Abstract Majority of men are affected by symptomatic benign prostatic hyperplasia (BPH) from a certain age. Botanical extracts are frequently used in the early management of the symptoms. In a sing...
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#1Fabian AlperthH-Index: 1
#2Ivana TurekH-Index: 1
Last.Franz BucarH-Index: 28
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Rhodiola rosea has been used in folk medicine as ethanolic macerates for a long time. This study aims to provide a quantitative and qualitative analysis and comparison of different ethanolic Rhodiola rosea rhizome macerates (35%, 70%, and 96% v/v) and accelerated solvent extraction (ASE) extracts prepared with 85% methanol, in order to shed light on the effectivity of different extraction methods. Extract samples were analyzed by UHPLC-DAD-ESI-MSn on a ZORBAX SB-C18 column (100 × 2.1 mm, 1.8 μm)...
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#1Fabian Alperth (University of Graz)H-Index: 1
#2Božena Mitić (University of Zagreb)H-Index: 10
Last.Franz Bucar (University of Graz)H-Index: 28
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AbstractIris adriatica Trinajstic ex Mitic (Iridaceae L.) is a strictly endemic taxon from Croatia. It is a rhizomatous dwarf plant from the I. pumila complex with a distribution area limited to the Croatian part of the Mediterranean area, mainly central Dalmatia. The genus Iris is known for its richness in isoflavonoids which also play a significant role in chemotaxonomy and biological activity. Hence, in the current study, different plant batches of I. adriatica collected in early spring of 20...
1 CitationsSource
#1Sandra Prasch (University of Graz)H-Index: 1
#2Alexandra G. Durán (UCA: University of Cádiz)H-Index: 4
Last.Franz Bucar (University of Graz)H-Index: 28
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Abstract Capsaicinoids are reported to have a bunch of promising pharmacological activities, among them antibacterial effects against various strains of bacteria. In this study the effect on efflux pumps of mycobacteria was investigated. The importance of efflux pumps, and the inhibition of these, is rising due to their involvement in antibiotic resistance development. In order to draw structure and activity relationships we tested natural and synthetical capsaicinoids as well as synthetical cap...
1 CitationsSource
#1Aleksandar Shkondrov (Sofia Medical University)H-Index: 4
#2Ilina Krasteva (Sofia Medical University)H-Index: 13
Last.Iliana Ionkova (Sofia Medical University)H-Index: 12
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AbstractA new tetracyclic saponin, 17(R),20(R)-3β,6α,16β-trihydroxycycloartanyl-23-carboxylic acid 16-lactone 3-O-β-D-glucopyranoside (1) together with one known flavonoid, camelliaside A (2) were ...
3 CitationsSource
#1Aleksandar Shkondrov (Sofia Medical University)H-Index: 4
#2Ilina Krasteva (Sofia Medical University)H-Index: 13
Last.Iliana Ionkova (Sofia Medical University)H-Index: 12
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Abstract Two novel compounds from A. glycyphylloides DC (1–2) and three rare flavonoids from A. spruneri Boiss. (3–5), alongside their neuroprotective activity and possible effects as human monoamine oxidase type B inhibitors were reported. The structural elucidation of the compounds was achieved by chemical, HRESIMS and NMR analyses. Their effects were investigated in vitro on isolated rat brain synaptosomes in 6-hydroxydopamine-induced toxicity. In addition, their effect on human monoamine oxi...
1 CitationsSource
#1Dongdong Wang (PAN: Polish Academy of Sciences)H-Index: 8
#2Verena Hiebl (University of Vienna)H-Index: 2
Last.Atanas G. Atanasov (PAN: Polish Academy of Sciences)H-Index: 31
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3 CitationsSource
#1Maja FriščićH-Index: 2
Last.Kroata Hazler PilepićH-Index: 5
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