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Eske Willerslev
University of Copenhagen
GenomeAncient DNAPopulationGeneticsBiology
364Publications
94H-index
26.9kCitations
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Publications 364
Newest
#1Riaan F. Rifkin (University of Pretoria)H-Index: 8
#2Surendra Vikram (University of Pretoria)H-Index: 11
Last. Matthieu Le Bailly (CNRS: Centre national de la recherche scientifique)H-Index: 15
view all 17 authors...
BACKGROUND: The archaeological incidence of ancient human faecal material provides a rare opportunity to explore the taxonomic composition and metabolic capacity of the ancestral human intestinal microbiome (IM). Here, we report the results of the shotgun metagenomic analyses of an ancient South African palaeo-faecal specimen. METHODS: Following the recovery of a single desiccated palaeo-faecal specimen from Bushman Rock Shelter in Limpopo Province, South Africa, we applied a multi-proxy analyti...
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#1Marie Louis (UCPH: University of Copenhagen)
#2Mikkel Skovrind (UCPH: University of Copenhagen)H-Index: 2
Last. Eva GardeH-Index: 5
view all 15 authors...
The Arctic is warming at an unprecedented rate, with unknown consequences for endemic fauna. However, Earth has experienced severe climatic oscillations in the past, and understanding how species responded to them might provide insight into their resilience to near-future climatic predictions. Little is known about the responses of Arctic marine mammals to past climatic shifts, but narwhals (Monodon monoceros) are considered one of the endemic Arctic species most vulnerable to environmental chan...
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#1Iain Mathieson (UPenn: University of Pennsylvania)H-Index: 21
#2Federico AbascalH-Index: 21
Last. M. S. Sandhu (University of Cambridge)H-Index: 61
view all 11 authors...
Baboons are one of the most abundant large nonhuman primates and are widely studied in biomedical, behavioral and anthropological research. Despite this, our knowledge of their evolutionary and demographic history remains incomplete. Here, we report a 0.9-fold coverage genome sequence from a 5800-year-old baboon from the site of Ha Makotoko in Lesotho. The ancient baboon is closely related to present-day Papio ursinus individuals from southern Africa-indicating a high degree of continuity in the...
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#1Frido Welker (UCPH: University of Copenhagen)H-Index: 8
#2Jazmín Ramos-Madrigal (UCPH: University of Copenhagen)H-Index: 5
Last. Marc de Manuel (CSIC: Spanish National Research Council)H-Index: 5
view all 26 authors...
The phylogenetic relationships between hominins of the Early Pleistocene epoch in Eurasia, such as Homo antecessor, and hominins that appear later in the fossil record during the Middle Pleistocene epoch, such as Homo sapiens, are highly debated1–5. For the oldest remains, the molecular study of these relationships is hindered by the degradation of ancient DNA. However, recent research has demonstrated that the analysis of ancient proteins can address this challenge6–8. Here we present the denta...
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Last. Thomas Higham (University of Oxford)H-Index: 61
view all 7 authors...
Abstract Excavations in 2010 on the Black Sea island of Sveti Ivan (Bulgaria) revealed the remains of a miniature marble sarcophagus containing human and animal remains, along with an inscribed tufa ossuary, beneath a 4th to 5th-century church floor. We found that the tufa ossuary had strong links with Cappadocian rhyolite tuff. The inscriptions on its surface suggest links to John the Baptist since they refer to him by name and contain a reference to his nativity date of June 24. The ancient Gr...
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#1Liisa Loog (University of Cambridge)H-Index: 3
#2Olaf Thalmann (Poznan University of Medical Sciences)H-Index: 11
Last. Andrea Manica (University of Cambridge)H-Index: 50
view all 36 authors...
Grey wolves (Canis lupus) are one of the few large terrestrial carnivores that have maintained a wide geographical distribution across the Northern Hemisphere throughout the Pleistocene and Holocene. Recent genetic studies have suggested that, despite this continuous presence, major demographic changes occurred in wolf populations between the Late Pleistocene and early Holocene, and that extant wolves trace their ancestry to a single Late Pleistocene population. Both the geographical origin of t...
3 CitationsSource
#1Sally Wasef (Griffith University)H-Index: 3
#1Sally Wasef (Griffith University)H-Index: 3
Last. David M. Lambert (Griffith University)H-Index: 39
view all 12 authors...
The ancient catacombs of Egypt harbor millions of well-preserved mummified Sacred Ibis (Threskiornis aethiopicus) dating from ~600BC. Although it is known that a very large number of these ‘votive’ mummies were sacrificed to the Egyptian God Thoth, how the ancient Egyptians obtained millions of these birds for mummification remains unresolved. Ancient Egyptian textual evidences suggest they may have been raised in dedicated large-scale farms. To investigate the most likely method used by the pri...
3 CitationsSource
#1Riaan F. Rifkin (University of Pretoria)H-Index: 8
#1R. F. Rifkin (UCPH: University of Copenhagen)
Last. Anders J. Hansen (UCPH: University of Copenhagen)H-Index: 29
view all 17 authors...
The archaeological incidence of ancient human faecal material provides a rare opportunity to explore the taxonomic composition and metabolic capacity of the ancestral human intestinal microbiome (IM). Following the recovery of a single desiccated palaeo-faecal specimen from Bushman Rock Shelter in Limpopo Province, South Africa, we applied a multi-proxy analytical protocol to the sample. Our results indicate that the distal IM of the Neolithic Middle Iron Age (c. AD 1485) Bantu-speaking individu...
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#1Maria Asplund (Wild Center)H-Index: 7
#2Kristín Rós Kjartansdóttir (Wild Center)H-Index: 6
Last. Anders J. Hansen (Wild Center)H-Index: 29
view all 23 authors...
Abstract Objectives Sample preparation for high-throughput sequencing (HTS) includes treatment with various laboratory components, potentially carrying viral nucleic acids, the extent of which has not been thoroughly investigated. Our aim was to systematically examine a diverse repertoire of laboratory components used to prepare samples for HTS in order to identify contaminating viral sequences. Methods A total of 322 samples of mainly human origin were analysed using eight protocols, applying a...
7 CitationsSource
#1Guillermo OliverH-Index: 58
#2Sandra Acosta (NU: Northwestern University)H-Index: 4
Last. Juergen A. Knoblich (Austrian Academy of Sciences)H-Index: 60
view all 15 authors...
The expansion of the mammalian brain is associated with specific developmental processes; however, not much is known about how evolutionary changes participated in the acquisition of human brain traits during early developmental stages. Here we investigated whether enhancers active during the phylotypic stage show human-specific genomic divergence which could contribute to the evolutionary expansion of the forebrain. Notably, we identified an active enhancer containing a human accelerated region...
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