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Alex O. Okaru
University of Nairobi
18Publications
5H-index
40Citations
Publications 19
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#1Alex O. Okaru (UoN: University of Nairobi)H-Index: 5
#2Jürgen Rehm (TUD: Dresden University of Technology)H-Index: 106
Last.Dirk W. LachenmeierH-Index: 4
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Abstract The World Health Organization estimates that globally out of the 6.2 L of pure alcohol consumed per person (15 + years), 25% is unrecorded alcohol. Unrecorded alcohol is defined as alcohol not registered in the legislation where it is consumed and includes homemade, surrogate, and counterfeit alcohols. Since the production, distribution, and consumption of unrecorded alcohol is not under official quality control and regulation, the risk of unrecorded alcohol containing potentially hazar...
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#1Alex O. Okaru (UoN: University of Nairobi)H-Index: 5
#2Anke RullmannH-Index: 2
Last.Dirk W. LachenmeierH-Index: 42
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Consumption of very hot (> 65 °C) beverages is probably associated with increased risk of oesophageal cancer. First associations were reported for yerba mate and it was initially believed that high content of polycyclic aromatic hydrocarbons (PAH) might explain the risk. Later research on other beverage groups such as tea and coffee, which are also consumed very hot, found associations with increased risk of oesophageal cancer as well. The risk may therefore not be inherent in any compound conta...
8 CitationsSource
#1Thomas KuballaH-Index: 27
#2Thomas Hausler (KIT: Karlsruhe Institute of Technology)H-Index: 4
Last.Dirk W. Lachenmeier (TUD: Dresden University of Technology)H-Index: 42
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Abstract Beverage fraud involving counterfeiting of brand spirits is an increasing problem not only due to deception of the consumer but also because it poses health risks e.g. from possible methanol admixture. Suspicious spirit samples from Russia and Kenya were analysed using 1 H nuclear magnetic resonance (NMR) spectroscopy in comparison to authentic products. Using linear regression analysis of spectral integral values, 4 counterfeited samples from Russia and 2 from Kenya were easily identif...
7 CitationsSource
#1Alex O. OkaruH-Index: 5
#2K.O. AbugaH-Index: 6
Last.Dirk W. LachenmeierH-Index: 42
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Cheap licit and artisanal illicit spirit drinks have been associated with numerous outbreaks of alcohol poisoning especially with methanol. This study aimed to evaluate the quality of cheap spirit drinks in Kibera slums in Nairobi County, Kenya. The samples consisted of cheap licit spirits (n = 11) and the artisanal spirit drink, ‘chang’aa’, (n = 28). The parameters of alcoholic strength and volatile composition were used as indicators of quality and were determined using gas chromatography with...
1 CitationsSource
#1Alex O. Okaru (UoN: University of Nairobi)H-Index: 5
#2K.O. Abuga (UoN: University of Nairobi)H-Index: 6
Last.Dirk W. Lachenmeier (TUD: Dresden University of Technology)H-Index: 42
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Abstract Samples of unrecorded opaque beers (n = 58; 40 based on maize, 5 on sorghum and 13 on other plants) and recorded wines (n = 8) in Kenya were screened for aflatoxins using a rapid ELISA technique followed by confirmation using liquid chromatography-tandem mass spectrometry. Six of the maize beers were obtained from Kibera slums in Nairobi County. Aflatoxin contamination was detected in six unrecorded beers (10%), but in none of the recorded wines. Remarkably, three of the aflatoxin posit...
5 CitationsSource
#1Alex O. Okaru (UoN: University of Nairobi)H-Index: 5
#2Dirk W. LachenmeierH-Index: 42
For decades, compounds present in foods and beverages have been implicated in the etiology of human cancers. The World Health Organization (WHO) International Agency for Research on Cancer (IARC) continues to classify such agents regarding their potential carcinogenicity in humans based on new evidence from animal and human studies. Furfuryl alcohol and β-myrcene are potential human carcinogens due to be evaluated. The major source of furfuryl alcohol in foods is thermal processing and ageing of...
11 CitationsSource
#1Alex O. OkaruH-Index: 5
#2K.O. AbugaH-Index: 6
Last.Dirk W. LachenmeierH-Index: 42
view all 5 authors...
A simple, isocratic and robust RP-HPLC method for the analysis of azithromycin was developed, validated and applied for the analysis of bulk samples, tablets and suspensions. The optimum chromatographic conditions for separation were established as a mobile phase comprised of acetonitrile-0.1 M KH2PO4 pH 6.5–0.1 M tetrabutyl ammonium hydroxide pH 6.5-water (25:15:1:59 v/v/v/v) delivered at a flow rate of 1.0 mL/min. The stationary phase consisted of reverse-phase XTerra® (250 mm × 4.6 mm i.d., 5...
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A simple, rapid, and selective quantitative nuclear magnetic resonance spectroscopic method was evaluated for the determination of the content of fluorinated pharmaceuticals. 19F NMR spectra were either obtained in dimethylsulfoxide-d6 or aqueous buffer, using trifluoroacetic acid as internal standard. Quantification of 13 fluorine-containing pharmaceuticals spanning various pharmacological classes was accomplished using the proposed method. The method was found to be fit for purpose (interday p...
6 CitationsSource
#1Alex O. Okaru (UoN: University of Nairobi)H-Index: 5
#2K.O. Abuga (UoN: University of Nairobi)H-Index: 6
Last.Dirk W. LachenmeierH-Index: 42
view all 5 authors...
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