Jilly Naaijen
Radboud University Nijmegen
Publications 30
#1Michael C. Craig ('KCL': King's College London)H-Index: 29
#2Leandra M Mulder (Radboud University Nijmegen)H-Index: 1
Last.Jilly Naaijen (Radboud University Nijmegen)H-Index: 6
view all 23 authors...
Abstract Disruptive behavior is associated with societally and personally problematic levels of aggression and has been linked to abnormal structure and function of fronto-amygdala-striatal regions. Abnormal glutamatergic signalling within this network may play a role in aggression. However, disruptive behavior does not represent a homogeneous construct, but can be fractionated across several dimensions. Of particular interest, callous-unemotional (CU) traits have been shown to modulate the seve...
Abstract Findings of executive functioning deficits in Tourette syndrome (TS) have so far been inconsistent, possibly due to methodological challenges of previous studies, such as the use of small sample sizes and not accounting for comorbid attention-deficit/hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), or medication use. We aimed to address these issues by examining several areas of executive functioning (response inhibition, attentional flexibility, cognitive control, an...
#1Renata B. Cupertino (UFRGS: Universidade Federal do Rio Grande do Sul)H-Index: 5
Last.Emma Sprooten (Radboud University Nijmegen)H-Index: 27
view all 20 authors...
Neuroimaging studies have associated Attention-Deficit/Hyperactivity Disorder (ADHD) with altered brain anatomy. However, small and heterogeneous study samples, and the use of region-of-interest and tissue-specific analyses have limited the consistency and replicability of these effects. The present study uses a fully data-driven multivariate approach to investigate alterations in both gray and white matter simultaneously, and capture neuroanatomical features associated with ADHD in two large, i...
#1Sophie E.A. Akkermans (Radboud University Nijmegen)H-Index: 4
#2N. Rheinheimer (Radboud University Nijmegen)H-Index: 1
Last.Philippe AubyH-Index: 1
view all 24 authors...
1 CitationsSource
#1Sophie E.A. Akkermans (Radboud University Nijmegen)H-Index: 4
#2Daan van Rooij (Radboud University Nijmegen)H-Index: 12
Last.Jan K. Buitelaar (Radboud University Nijmegen)H-Index: 104
view all 9 authors...
Abstract Attention-deficit/hyperactivity disorder (ADHD) is the most common comorbidity in individuals with Tourette syndrome (TS). Yet, it is unclear to what extent TS and ADHD show overlapping or distinct neural abnormalities. ADHD has been associated with altered reward processing, but there are very few studies on reward processing in TS. This study assessed neural activation of basal ganglia and thalamus during reward anticipation and receipt in children with TS and/or ADHD. We analysed mea...
#1Christienne G. Damatac (Radboud University Nijmegen)H-Index: 3
#2Marcel P. Zwiers (Radboud University Nijmegen)H-Index: 38
Last.Emma Sprooten (Radboud University Nijmegen)H-Index: 27
view all 13 authors...
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by age-inappropriate levels of inattention and/or hyperactivity-impulsivity. ADHD has been related to differences in white matter microstructure, measured by diffusion-weighted imaging (DWI) and quantified by fractional anisotropy (FA). In the largest DWI analysis of ADHD to date, we systematically investigated if FA is associated with: current and lifetime diagnosis, categorical diagnosis and continuo...
#2Roselyne ChauvinH-Index: 3
Last.Christian F. Beckmann (University of Oxford)H-Index: 64
view all 6 authors...
Functional connectivity between brain regions is modulated by cognitive states or experimental conditions. Such connectivity variations can be appreciated in covariance or correlation matrices obtained from fMRI data. A multivariate methodology that can capture fMRI connectivity maps in light of different experimental conditions would be of primary importance to learn about the specific roles of the different brain areas involved in the observed connectivity variations. Here we introduce Spatial...
#1Julia E Werhahn (UZH: University of Zurich)H-Index: 1
#2Susanna Mohl (UZH: University of Zurich)H-Index: 1
Last.Daniel Brandeis (UZH: University of Zurich)H-Index: 57
view all 33 authors...
Background. Disruptive behavior in children and adolescents can manifest itself in reactive (RA) and proactive (PA) aggression and is modulated by callous-unemotional (CU) traits and comorbidity. Research on aggression subtype-specific neural correlates is limited and the role of comorbid symptoms largely neglected. Methods. The current multi-center study extended previous efforts by investigating unrestricted resting state functional connectivity (rsFC) alterations. The large sample (n = 207) o...
#1Bram Gooskens (UU: Utrecht University)
#2Dienke J. Bos (UU: Utrecht University)H-Index: 11
Last.Sarah Durston (UU: Utrecht University)H-Index: 36
view all 12 authors...
Abstract Repetitive behaviors are among the core symptoms of both Autism Spectrum Disorder (ASD) and Obsessive-Compulsive Disorder (OCD) and are thought to be associated with impairments in cognitive control. However, it is still unknown how deficits in cognitive control and associated neural circuitry relate to the quality or severity of repetitive behavior in children with these disorders. Therefore, we investigated the behavioral and neural correlates of cognitive control using a modified sto...