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Anjan Talukdar
University of Pittsburgh
ImmunologyLymphocyteImmunosuppressionTacrolimusMedicine
6Publications
4H-index
93Citations
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Publications 6
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#1Anjan Talukdar (University of Pittsburgh)H-Index: 4
#2Chethan Ashokkumar (University of Pittsburgh)H-Index: 12
Last. Rakesh Sindhi (University of Pittsburgh)H-Index: 32
view all 10 authors...
: Multiple measurements (n = 212) of lymphocyte subsets in 67 children treated with steroid-free Tacrolimus, and rabbit anti-human thymocyte globulin induction demonstrate early reconstitution of T-cytotoxic and NK cells. Reconstitution of CD4+ cells is complete after the second post-transplant year. During the period at risk for rejection, NK and T-cytotoxic cell counts are significantly higher among Rejectors. During periods at increased risk for EBV viral infection, CD4 counts bear a signific...
7 CitationsSource
#1Anjan Talukdar (University of Pittsburgh)H-Index: 4
#2Chethan Ashokkumar (University of Pittsburgh)H-Index: 12
Last. Rakesh Sindhi (University of Pittsburgh)H-Index: 32
view all 7 authors...
Multiple measurements of lymphocyte subsets in 91 children treated with steroid-free tacrolimus, and rabbit anti-human thymocyte globulin induction demonstrate early reconstitution of T-cytotoxic cells, and gradual reconstitution of all other subsets, which is complete after one yr. Rejection-prone children demonstrate significantly higher counts of lymphocytes and all subsets prior to liver transplantation, and may exemplify one basis for enhanced baseline immunocompetence.
9 CitationsSource
#1Chethan Ashokkumar (University of Pittsburgh)H-Index: 12
#2Anjan Talukdar (University of Pittsburgh)H-Index: 4
Last. Rakesh Sindhi (University of Pittsburgh)H-Index: 32
view all 15 authors...
Antigen-specific T-cells, which express CD154 rapidly, but remain untested in alloimmunity, were measured with flow cytometry in 16-hour MLR of 58 identically-immunosuppressed children with liver transplantation (LTx), to identify Rejectors (who had experienced biopsyproven rejection within 60 days post-transplantation). Thirty one children were sampled once, cross-sectionally. Twenty seven children were sampled longitudinally, pre-LTx, and at 1–60 and 61–200 days after LTx. Results were correla...
63 CitationsSource
#1Rakesh Sindhi (Boston Children's Hospital)H-Index: 32
#2Brandon W. Higgs (Boston Children's Hospital)H-Index: 30
Last. Robert E. Ferrell (University of Pittsburgh)H-Index: 89
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Background & Aims: Limited access to large samples precludes genome-wide association studies of rare but complex traits. To localize candidate genes with family-based genome-wide association, a novel exploratory analysis was first tested on 1774 major histocompatibility complex single nucleotide polymorphisms (SNPs) in 240 DNA samples from 80 children with primary liver transplantation and their biologic parents. Methods: Initially, 57 SNPs with large differences ( P Results: In hypothesis testi...
13 CitationsSource
#2Ali AbdullahH-Index: 2
Last. Rakesh SindhiH-Index: 32
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1 CitationsSource
#1Rakesh Sindhi (University of Pittsburgh)H-Index: 32
#2Anjan Talukdar (University of Pittsburgh)H-Index: 4
Last. George Mazareigos (University of Pittsburgh)H-Index: 1
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